Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Found 562 products of "Calcium Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Mibefradil
CAS:Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).Formula:C29H38FN3O3Purity:98%Color and Shape:SolidMolecular weight:495.63SB-423557
CAS:SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFormula:C28H36N2O4Purity:98%Color and Shape:SolidMolecular weight:464.60Emopamil
CAS:Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.Formula:C23H30N2Color and Shape:SolidMolecular weight:334.5Leualacin
CAS:Leualacin is a novel calcium blocker from Hapsidospora irregularis.Formula:C31H47N3O7Purity:98%Color and Shape:SolidMolecular weight:573.72PD-217014
CAS:PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.Formula:C10H17NO2Color and Shape:SolidMolecular weight:183.25Sesamodil
CAS:Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.Formula:C29H32N2O6SPurity:98.87% - 99.87%Color and Shape:SolidMolecular weight:536.64PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Color and Shape:SolidMolecular weight:535.63MP-010
CAS:MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.Formula:C14H20N4O2SColor and Shape:SolidMolecular weight:308.399Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formula:C29H42Cl2FN3O4Color and Shape:SolidMolecular weight:586.57Cav 3.1 blocker 1
CAS:Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM).Formula:C26H19F6N3O2Color and Shape:SolidMolecular weight:519.438Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Formula:C32H37F2N3OColor and Shape:SolidMolecular weight:517.65T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78AZD 2066 hydrate
AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].Formula:C19H18ClN5O3Color and Shape:SolidMolecular weight:386.33Calpain Inhibitor-2
CAS:Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.Formula:C26H33N3O5SColor and Shape:SolidMolecular weight:499.62TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formula:C19H27Cl2FN2OColor and Shape:SolidMolecular weight:389.33IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Formula:C15H14F3NO2Color and Shape:SolidMolecular weight:297.27Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Formula:C32H39N3OColor and Shape:SolidMolecular weight:481.67SR 33805 oxalate
CAS:Ca2+ channel antagonistFormula:C34H42N2O9SPurity:98%Color and Shape:SolidMolecular weight:654.77IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Formula:C16H13F6NO2Color and Shape:SolidMolecular weight:365.27Verapamil EP Impurity C hydrochloride
CAS:NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Formula:C12H20ClNO2Color and Shape:SolidMolecular weight:245.75
