Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Found 573 products of "Calcium Channel"
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Huwentoxin I
CAS:Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36Mipsagargin
CAS:Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.Formula:C66H100N6O27Purity:98%Color and Shape:SolidMolecular weight:1409.52Nesiritide acetate
CAS:Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Formula:C143H244N50O42S4C2H4O2Color and Shape:SolidMolecular weight:3524.1Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Color and Shape:LiquidChlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Formula:C7H7ClOColor and Shape:SolidMolecular weight:142.58ω-Agatoxin TK
CAS:Selective blocker of CaV2.1 P/Q-type calcium channels.Formula:C215H337N65O70S10Purity:98%Color and Shape:SolidMolecular weight:5273.02PACAP-38 (31-38), human, mouse, rat
CAS:PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFormula:C47H83N17O11Purity:98%Color and Shape:SolidMolecular weight:1062.27Candidalysin
CAS:Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.Formula:C153H266N38O38S2Color and Shape:SolidMolecular weight:3310.11sFTX-3.3
CAS:sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.Formula:C12H29N7OColor and Shape:SolidMolecular weight:287.412MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Formula:C75H123N19O18SPurity:98%Color and Shape:SolidMolecular weight:1610.97Katacalcin
CAS:Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].Formula:C97H154N34O36S2Purity:98%Color and Shape:White PowderMolecular weight:2436.6Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Formula:C324H478N94O90S8Purity:98%Color and Shape:SolidMolecular weight:7386.36SG-094
CAS:SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.
Formula:C30H29NO3Purity:97.06%Color and Shape:SoildMolecular weight:451.56(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Formula:C13H12Cl2O4Purity:98%Color and Shape:SolidMolecular weight:308.17ω-Conotoxin GVIA
CAS:Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Formula:C120H182N38O43S6Purity:98%Color and Shape:SolidMolecular weight:3037UK-59811 hydrochloride
CAS:UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85Ziconotide
CAS:Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Formula:C102H172N36O32S7Purity:98%Color and Shape:White PowderMolecular weight:2639.131-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(
Formula:C5H10ClNO2Purity:>99.99%Color and Shape:SolidMolecular weight:151.59
