CymitQuimica logo
OAT

OAT

Organic anion transporters are a family of membrane proteins that mediate the uptake and excretion of various endogenous and exogenous organic anions, including drugs, toxins, and metabolic byproducts. OATs are primarily expressed in the kidneys and liver, where they play a crucial role in detoxification and drug clearance. Dysregulation of OAT function can lead to drug toxicity and kidney disorders. At CymitQuimica, we provide a variety of OAT modulators to support your research in pharmacology, toxicology, and renal function.

Found 27 products of "OAT"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • URAT1 inhibitor 1
    Targetmol
    + Info

    URAT1 inhibitor 1

    CAS:
    <p>URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.</p>
    Formula:C19H15Br2N5O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:569.29

    Ref: TM-T13259

  • KPH2f
    Targetmol
    + Info

    KPH2f

    CAS:
    <p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>
    Formula:C24H16N3NaO2S
    Color and Shape:Solid
    Molecular weight:433.46

    Ref: TM-T62432

  • Cyazofamid
    Targetmol
    + Info

    Cyazofamid

    CAS:
    <p>Cyazofamid functions as a fungicide by impairing the production of ATP. It inhibits Organic Cation Transporter 3 (OCT3) and OAT1 with IC50 values of 1.54 and 17.3 μM, respectively.</p>
    Formula:C13H13ClN4O2S
    Color and Shape:Solid
    Molecular weight:324.79

    Ref: TM-T201605

  • hURAT1 inhibitor 2
    Targetmol
    + Info

    hURAT1 inhibitor 2

    CAS:
    <p>hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.</p>
    Formula:C17H11Br2FO3
    Color and Shape:Solid
    Molecular weight:442.074

    Ref: TM-T206558

  • CymitQuimica logo
    Targetmol
    + Info

    URAT1 inhibitor 3

    <p>URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.</p>
    Formula:C14H8Cl2N2O2
    Color and Shape:Solid
    Molecular weight:307.13

    Ref: TM-T60724

  • CymitQuimica logo
    Targetmol
    + Info

    URAT1 inhibitor 2

    <p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>
    Formula:C21H18BrN3O2S
    Color and Shape:Solid
    Molecular weight:456.36

    Ref: TM-T62825

  • TRPV1 antagonist 10
    Targetmol
    + Info

    TRPV1 antagonist 10

    CAS:
    <p>TRPV1 antagonist 10 is a potent, orally active TRPV1 antagonist with an IC50 of 33.06 nM and serves as a moderate to weak inhibitor of URAT1 (IC50 = 22.51 μM) and GLUT9 (inhibition of 60.25% at 50 μM). It exhibits analgesic and urate-lowering properties and is applicable for research in hyperuricemia and inflammatory pain.</p>
    Formula:C16H14N2O5
    Color and Shape:Solid
    Molecular weight:314.293

    Ref: TM-T207037