
Glucokinase
Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.
Found 53 products of "Glucokinase"
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MK-0941
CAS:<p>MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.</p>Formula:C22H28N4O9S2Color and Shape:SolidMolecular weight:556.61Hex
CAS:<p>Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.</p>Formula:C5H10NO5PColor and Shape:SolidMolecular weight:195.11GKA50
CAS:<p>GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).</p>Formula:C26H28N2O6Purity:98%Color and Shape:SolidMolecular weight:464.51
