UGT
UDP-Glucuronosyltransferases (UGTs) are enzymes involved in the detoxification of xenobiotics and endogenous compounds by catalyzing the glucuronidation process, which makes these substances more water-soluble and easier to excrete. UGT inhibitors are important in the study of drug metabolism, as they can alter the pharmacokinetics of therapeutic agents and influence drug efficacy and toxicity. These inhibitors are also used to investigate the role of UGTs in various diseases, including cancer and liver disorders. At CymitQuimica, we offer UGT inhibitors to support your research in toxicology, pharmacokinetics, and drug development.
Found 5 products for "UGT".
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Cremophor EL
CAS:Cremophor EL is a nonionic surfactant. cremophor EL inhibits cellular metabolism and suppresses UGT1A1-mediated rhodopsin glucuronidation.Formula:C4H7Cl2NO2Color and Shape:Yellow LiquidMolecular weight:172.01UGT8-IN-1
CAS:UGT8-IN-1 is a BBB-penetrant UGT8 inhibitor used in research on sphingolipid-related neurological disorders.Formula:C20H22F6N4O4SPurity:99.60%Color and Shape:White SolidMolecular weight:528.47α-Angelica lactone
CAS:α-Angelica lactone is a vinyl nucleophilic reagent and a naturally occurring anticancer agent. α-Angelica lactone has cardiotonic activity.Formula:C5H6O2Purity:99.79%Color and Shape:Transparent LiquidMolecular weight:98.1UK-157147
CAS:UK-157147 is a substrate for UGT1A1(Km: 105 μM).Formula:C23H24N2O7SPurity:98%Color and Shape:SolidMolecular weight:472.51UGT1A1-IN-1
CAS:UGT1A1-IN-1 is a non-competitive UGT1A1 inhibitor (IC50 = 1.33 μM). Serving as a fluorescent probe substrate, it is used to study bilirubin metabolism and liver microsomal drug metabolism.Formula:C22H19NO3Purity:98.93%Color and Shape:Yellow SolidMolecular weight:345.39Ref: TM-T87592
1mg117.00€5mg281.00€1mL*10mM (DMSO)310.00€10mg444.00€25mg888.00€50mg1,431.00€100mg2,178.00€
