Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Found 177 products of "Carbonic Anhydrase"
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hCAXII-IN-5
CAS:<p>hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.</p>Formula:C23H22N2O4Color and Shape:SolidMolecular weight:390.43AHR-15010
CAS:<p>AHR-15010 is a novel anti-arthritic agent.</p>Formula:C10H16N2O8S2Purity:98%Color and Shape:SolidMolecular weight:356.37L-693612 HCl
CAS:<p>L-693612 HCl is an inhibitor of carbonic anhydrase.</p>Formula:C14H25ClN2O5S3Purity:98%Color and Shape:SolidMolecular weight:433.01hCAIX-IN-7
CAS:<p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).</p>Formula:C18H12FNO3Color and Shape:SolidMolecular weight:309.29Carbonic anhydrase inhibitor 13
CAS:<p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>Formula:C17H15N5O3S2Color and Shape:SolidMolecular weight:401.46hCAIX-IN-3
CAS:<p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>Formula:C21H21BrN6O4SColor and Shape:SolidMolecular weight:533.4hCAIX-IN-14
CAS:<p>hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .</p>Formula:C11H17ClN6O2SColor and Shape:SolidMolecular weight:332.81Carbonic anhydrase inhibitor 7
CAS:<p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>Formula:C23H17N3O5SColor and Shape:SolidMolecular weight:447.46hCAXII-IN-1
CAS:<p>hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.</p>Formula:C20H17NO5Color and Shape:SolidMolecular weight:351.35Quinethazone
CAS:<p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>Formula:C10H12ClN3O3SColor and Shape:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Molecular weight:289.74hCAIX-IN-10
CAS:<p>"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."</p>Formula:C28H21N3O3SColor and Shape:SolidMolecular weight:479.55hCAIX-IN-6
CAS:<p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>Formula:C18H12N2O4SColor and Shape:SolidMolecular weight:352.36DTP348
CAS:<p>DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.</p>Formula:C6H11N5O4SColor and Shape:SolidMolecular weight:249.25Carbonic anhydrase inhibitor 11
CAS:<p>Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.</p>Formula:C19H15F3N4O3S2Color and Shape:SolidMolecular weight:468.47hCAIX/XII-IN-4
CAS:<p>hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).</p>Formula:C20H16N2O5Color and Shape:SolidMolecular weight:364.35hCAXII-IN-4
CAS:<p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>Formula:C22H27N5O6SColor and Shape:SolidMolecular weight:489.54hCAI/II-IN-2
CAS:<p>hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.</p>Formula:C12H12N4O5S2Color and Shape:SolidMolecular weight:356.38hCA IX-IN-2
<p>hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative</p>Formula:C23H24N2O4STeColor and Shape:SolidMolecular weight:552.11hCAI/II-IN-3
CAS:<p>"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."</p>Formula:C16H18N4O4S2Color and Shape:SolidMolecular weight:394.47hCAIX/XII-IN-6
<p>hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.</p>Formula:C26H23N3O6S4Color and Shape:SolidMolecular weight:601.74hCAII-IN-1
CAS:<p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>Formula:C21H21BrN6O4SColor and Shape:SolidMolecular weight:533.4hCAIX-IN-8
CAS:<p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>Formula:C19H16N4O6Color and Shape:SolidMolecular weight:396.35hCAXII-IN-2
CAS:<p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>Formula:C21H18ClN3O4Color and Shape:SolidMolecular weight:411.84hCA I-IN-2
CAS:<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Formula:C26H20BrN5O3SColor and Shape:SolidMolecular weight:562.44FC11409B
CAS:<p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>Formula:C29H23BF4N2O3SColor and Shape:SolidMolecular weight:566.38hCAI/II-IN-4
CAS:<p>hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>Formula:C15H15N3O5S2Color and Shape:SolidMolecular weight:381.43Methazolamide-d6
CAS:<p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>Formula:C5H2D6N4O3S2Color and Shape:SolidMolecular weight:242.31L 662583
CAS:<p>L 662583 is a topical inhibitor of carbonic anhydrase.</p>Formula:C13H17ClN2O5S3Purity:98%Color and Shape:SolidMolecular weight:412.93L-693612
CAS:<p>L-693612 is an inhibitor of carbonic anhydrase.</p>Formula:C14H24N2O5S3Purity:98%Color and Shape:SolidMolecular weight:396.55L 645151
CAS:<p>L 645151 is an inhibitor of lipophilic CA.</p>Formula:C12H14N2O4S2Color and Shape:SolidMolecular weight:314.38hCAIX-IN-5
CAS:<p>hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.</p>Formula:C18H12FNO3Purity:99.26%Color and Shape:SolidMolecular weight:309.29WES-1
CAS:<p>WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,</p>Formula:C20H20N4O3SPurity:98%Color and Shape:SolidMolecular weight:396.46hCAI/II-IN-6
CAS:<p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>Formula:C19H24N4O3SPurity:97.07%Color and Shape:SolidMolecular weight:388.48hCAII-IN-9
CAS:<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Formula:C15H16ClN3O5S2Purity:98.63%Color and Shape:SolidMolecular weight:417.89Sultiame
CAS:<p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>Formula:C10H14N2O4S2Purity:99.91%Color and Shape:SolidMolecular weight:290.36Carbonic anhydrase inhibitor 6
CAS:<p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>Formula:C26H25N3O5SPurity:98.81%Color and Shape:SolidMolecular weight:491.56hCAIX/XII-IN-8
CAS:<p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>Formula:C16H13Cl2N5O3SPurity:98%Color and Shape:SolidMolecular weight:426.28Carbonic anhydrase inhibitor 12
CAS:<p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>Formula:C27H22BrN5O5S2Purity:98%Color and Shape:SolidMolecular weight:640.53N-Desethyl Brinzolamide oxalate
CAS:<p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>Formula:C12H19N3O9S3Color and Shape:SolidMolecular weight:445.49COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41hCAIX-IN-16
CAS:<p>hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.</p>Formula:C20H20N8O2SPurity:98%Color and Shape:SolidMolecular weight:436.49ALP/Carbonic anhydrase-IN-1
CAS:<p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>Formula:C15H16N2Purity:98%Color and Shape:SolidMolecular weight:224.3CAXII-IN-1
CAS:<p>CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.</p>Formula:C13H7Cl2NO3SColor and Shape:SolidMolecular weight:328.17hCAIX-IN-15
CAS:<p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>Formula:C18H14FN7O2SPurity:98%Color and Shape:SolidMolecular weight:411.41CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formula:C18H19BrN4SColor and Shape:SolidMolecular weight:403.34Carbonic anhydrase inhibitor 5
<p>Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.</p>Formula:C24H20ClN3O3SColor and Shape:SolidMolecular weight:465.95Carbonic anhydrase inhibitor 9
<p>Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.</p>Formula:C22H20BrN5O4SColor and Shape:SolidMolecular weight:530.39hCAII-IN-5
CAS:<p>hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].</p>Formula:C29H18N2O7Color and Shape:SolidMolecular weight:506.46hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formula:C17H21N3O3SColor and Shape:SolidMolecular weight:347.43Valerate sodium
CAS:<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formula:C5H9NaO2Purity:99.84%Color and Shape:SolidMolecular weight:124.11O-Desmethyl Brinzolamide hydrochloride
CAS:<p>O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].</p>Formula:C11H20ClN3O5S3Color and Shape:SolidMolecular weight:405.94hCAIX/XII-IN-15
CAS:<p>hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.</p>Formula:C17H18O4SColor and Shape:SolidMolecular weight:318.387Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formula:C21H18N2O4SColor and Shape:SolidMolecular weight:394.44Perfluorohexane sulfonamide
CAS:<p>Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.</p>Formula:C6H2F13NO2SColor and Shape:SolidMolecular weight:399.13AChE/CA I-IN-1
<p>AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.</p>Formula:C14H19NO6SColor and Shape:SolidMolecular weight:329.374-Acetylphenylboronic acid
CAS:<p>4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).</p>Formula:C8H9BO3Color and Shape:SolidMolecular weight:163.97CA IX-IN-1
<p>CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.</p>Formula:C16H22N4O8SColor and Shape:SolidMolecular weight:430.43hCAI/II/XII-IN-1
CAS:<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Formula:C12H12N2O2SColor and Shape:SolidMolecular weight:248.301CA IX-IN-3
CAS:<p>CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.</p>Formula:C21H19N5O4S2Color and Shape:SolidMolecular weight:469.537Carbonic anhydrase inhibitor 17
CAS:<p>Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.</p>Formula:C18H15ClN4O3S2Molecular weight:434.92Carbonic anhydrase inhibitor 16
CAS:<p>Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.</p>Formula:C14H10N2O4SPurity:99.65%Color and Shape:SolidMolecular weight:302.31CAII-IN-1
<p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>Formula:C19H21FN4SColor and Shape:SolidMolecular weight:356.46Sulclamide
CAS:<p>Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].</p>Formula:C7H7ClN2O3SColor and Shape:SolidMolecular weight:234.66hCAVII/IX-IN-1
CAS:<p>hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.</p>Formula:C7H7N3O2S2Color and Shape:SolidMolecular weight:229.279CAII-IN-3
<p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>Formula:C18H18F2N4SColor and Shape:SolidMolecular weight:360.42β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52Carbonic anhydrase inhibitor 19
CAS:<p>Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.</p>Formula:C23H25N3O6S2Molecular weight:503.59Carbonic anhydrase inhibitor 2
CAS:<p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>Formula:C12H16N4O6SColor and Shape:SolidMolecular weight:344.34α-Glucosidase-IN-63
CAS:<p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>Formula:C16H12FN3O3S2Color and Shape:SolidMolecular weight:377.41hCAII-IN-4
CAS:<p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>Formula:C31H23NO9Color and Shape:SolidMolecular weight:553.52Carbonic anhydrase inhibitor 8
<p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5Carbonic anhydrase inhibitor 3
<p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>Formula:C15H17N3O3SColor and Shape:SolidMolecular weight:319.38hCA XII/II/IX-IN-1
<p>hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.</p>Formula:C25H34N4O7SColor and Shape:SolidMolecular weight:534.63Carbonic anhydrase inhibitor 10
<p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>Formula:C14H17N5O3SColor and Shape:SolidMolecular weight:335.38β-Glucuronidase/hCAII-IN-1
CAS:<p>β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50</p>Formula:C30H21NO9Color and Shape:SolidMolecular weight:539.49NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Formula:C21H19N9O2SColor and Shape:SolidMolecular weight:461.5hCA VB-IN-1
<p>hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].</p>Formula:C9H13N3O4SColor and Shape:SolidMolecular weight:259.28
