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Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.

Found 177 products of "Carbonic Anhydrase"

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  • hCAII-IN-1

    CAS:
    <p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>
    Formula:C21H21BrN6O4S
    Color and Shape:Solid
    Molecular weight:533.4
  • hCAIX-IN-8

    CAS:
    <p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>
    Formula:C19H16N4O6
    Color and Shape:Solid
    Molecular weight:396.35
  • hCAXII-IN-2

    CAS:
    <p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>
    Formula:C21H18ClN3O4
    Color and Shape:Solid
    Molecular weight:411.84
  • hCA I-IN-2

    CAS:
    <p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>
    Formula:C26H20BrN5O3S
    Color and Shape:Solid
    Molecular weight:562.44
  • FC11409B

    CAS:
    <p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>
    Formula:C29H23BF4N2O3S
    Color and Shape:Solid
    Molecular weight:566.38
  • hCAI/II-IN-4

    CAS:
    <p>hCAI/II-IN-4 inhibits hCA I &amp; II (Ki: 16.95 &amp; 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>
    Formula:C15H15N3O5S2
    Color and Shape:Solid
    Molecular weight:381.43
  • Methazolamide-d6

    CAS:
    <p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>
    Formula:C5H2D6N4O3S2
    Color and Shape:Solid
    Molecular weight:242.31
  • L 662583

    CAS:
    <p>L 662583 is a topical inhibitor of carbonic anhydrase.</p>
    Formula:C13H17ClN2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:412.93
  • L-693612

    CAS:
    <p>L-693612 is an inhibitor of carbonic anhydrase.</p>
    Formula:C14H24N2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:396.55
  • L 645151

    CAS:
    <p>L 645151 is an inhibitor of lipophilic CA.</p>
    Formula:C12H14N2O4S2
    Color and Shape:Solid
    Molecular weight:314.38
  • hCAIX-IN-5

    CAS:
    <p>hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of &gt;10000, &gt;10000, 130.7, and 829.1 nM, respectively.</p>
    Formula:C18H12FNO3
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:309.29
  • WES-1

    CAS:
    <p>WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,</p>
    Formula:C20H20N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:396.46
  • hCAI/II-IN-6

    CAS:
    <p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>
    Formula:C19H24N4O3S
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:388.48
  • hCAII-IN-9

    CAS:
    <p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>
    Formula:C15H16ClN3O5S2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:417.89
  • Sultiame

    CAS:
    <p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>
    Formula:C10H14N2O4S2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:290.36
  • Carbonic anhydrase inhibitor 6

    CAS:
    <p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>
    Formula:C26H25N3O5S
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:491.56
  • hCAIX/XII-IN-8

    CAS:
    <p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>
    Formula:C16H13Cl2N5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.28
  • Carbonic anhydrase inhibitor 12

    CAS:
    <p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>
    Formula:C27H22BrN5O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.53
  • N-Desethyl Brinzolamide oxalate

    CAS:
    <p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>
    Formula:C12H19N3O9S3
    Color and Shape:Solid
    Molecular weight:445.49
  • COX-2-IN-30

    CAS:
    <p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>
    Formula:C17H16N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.41