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Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.

Found 177 products of "Carbonic Anhydrase"

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  • hCAXII-IN-5

    CAS:
    <p>hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI &amp; II &gt;10000, hCAIX 286.1, hCAXII 1.0 nM.</p>
    Formula:C23H22N2O4
    Color and Shape:Solid
    Molecular weight:390.43
  • AHR-15010

    CAS:
    <p>AHR-15010 is a novel anti-arthritic agent.</p>
    Formula:C10H16N2O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.37
  • L-693612 HCl

    CAS:
    <p>L-693612 HCl is an inhibitor of carbonic anhydrase.</p>
    Formula:C14H25ClN2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.01
  • hCAIX-IN-7

    CAS:
    <p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: &gt;10000 nM).</p>
    Formula:C18H12FNO3
    Color and Shape:Solid
    Molecular weight:309.29
  • Carbonic anhydrase inhibitor 13

    CAS:
    <p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>
    Formula:C17H15N5O3S2
    Color and Shape:Solid
    Molecular weight:401.46
  • hCAIX-IN-3

    CAS:
    <p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>
    Formula:C21H21BrN6O4S
    Color and Shape:Solid
    Molecular weight:533.4
  • hCAIX-IN-14

    CAS:
    <p>hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .</p>
    Formula:C11H17ClN6O2S
    Color and Shape:Solid
    Molecular weight:332.81
  • Carbonic anhydrase inhibitor 7

    CAS:
    <p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>
    Formula:C23H17N3O5S
    Color and Shape:Solid
    Molecular weight:447.46
  • hCAXII-IN-1

    CAS:
    <p>hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.</p>
    Formula:C20H17NO5
    Color and Shape:Solid
    Molecular weight:351.35
  • Quinethazone

    CAS:
    <p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>
    Formula:C10H12ClN3O3S
    Color and Shape:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)
    Molecular weight:289.74
  • hCAIX-IN-10

    CAS:
    <p>"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."</p>
    Formula:C28H21N3O3S
    Color and Shape:Solid
    Molecular weight:479.55
  • hCAIX-IN-6

    CAS:
    <p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>
    Formula:C18H12N2O4S
    Color and Shape:Solid
    Molecular weight:352.36
  • DTP348

    CAS:
    <p>DTP348: Oral carbonic anhydrase IX inhibitor &amp; hypoxic cell radiosensitizer with sulfamide &amp; 5-nitroimidazole components.</p>
    Formula:C6H11N5O4S
    Color and Shape:Solid
    Molecular weight:249.25
  • Carbonic anhydrase inhibitor 11

    CAS:
    <p>Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.</p>
    Formula:C19H15F3N4O3S2
    Color and Shape:Solid
    Molecular weight:468.47
  • hCAIX/XII-IN-4

    CAS:
    <p>hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and &gt;10000 nM (CAI/CAII).</p>
    Formula:C20H16N2O5
    Color and Shape:Solid
    Molecular weight:364.35
  • hCAXII-IN-4

    CAS:
    <p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>
    Formula:C22H27N5O6S
    Color and Shape:Solid
    Molecular weight:489.54
  • hCAI/II-IN-2

    CAS:
    <p>hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.</p>
    Formula:C12H12N4O5S2
    Color and Shape:Solid
    Molecular weight:356.38
  • hCA IX-IN-2


    <p>hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative</p>
    Formula:C23H24N2O4STe
    Color and Shape:Solid
    Molecular weight:552.11
  • hCAI/II-IN-3

    CAS:
    <p>"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."</p>
    Formula:C16H18N4O4S2
    Color and Shape:Solid
    Molecular weight:394.47
  • hCAIX/XII-IN-6


    <p>hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.</p>
    Formula:C26H23N3O6S4
    Color and Shape:Solid
    Molecular weight:601.74
  • hCAII-IN-1

    CAS:
    <p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>
    Formula:C21H21BrN6O4S
    Color and Shape:Solid
    Molecular weight:533.4
  • hCAIX-IN-8

    CAS:
    <p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>
    Formula:C19H16N4O6
    Color and Shape:Solid
    Molecular weight:396.35
  • hCAXII-IN-2

    CAS:
    <p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>
    Formula:C21H18ClN3O4
    Color and Shape:Solid
    Molecular weight:411.84
  • hCA I-IN-2

    CAS:
    <p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>
    Formula:C26H20BrN5O3S
    Color and Shape:Solid
    Molecular weight:562.44
  • FC11409B

    CAS:
    <p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>
    Formula:C29H23BF4N2O3S
    Color and Shape:Solid
    Molecular weight:566.38
  • hCAI/II-IN-4

    CAS:
    <p>hCAI/II-IN-4 inhibits hCA I &amp; II (Ki: 16.95 &amp; 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>
    Formula:C15H15N3O5S2
    Color and Shape:Solid
    Molecular weight:381.43
  • Methazolamide-d6

    CAS:
    <p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>
    Formula:C5H2D6N4O3S2
    Color and Shape:Solid
    Molecular weight:242.31
  • L 662583

    CAS:
    <p>L 662583 is a topical inhibitor of carbonic anhydrase.</p>
    Formula:C13H17ClN2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:412.93
  • L-693612

    CAS:
    <p>L-693612 is an inhibitor of carbonic anhydrase.</p>
    Formula:C14H24N2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:396.55
  • L 645151

    CAS:
    <p>L 645151 is an inhibitor of lipophilic CA.</p>
    Formula:C12H14N2O4S2
    Color and Shape:Solid
    Molecular weight:314.38
  • hCAIX-IN-5

    CAS:
    <p>hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of &gt;10000, &gt;10000, 130.7, and 829.1 nM, respectively.</p>
    Formula:C18H12FNO3
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:309.29
  • WES-1

    CAS:
    <p>WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,</p>
    Formula:C20H20N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:396.46
  • hCAI/II-IN-6

    CAS:
    <p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>
    Formula:C19H24N4O3S
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:388.48
  • hCAII-IN-9

    CAS:
    <p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>
    Formula:C15H16ClN3O5S2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:417.89
  • Sultiame

    CAS:
    <p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>
    Formula:C10H14N2O4S2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:290.36
  • Carbonic anhydrase inhibitor 6

    CAS:
    <p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>
    Formula:C26H25N3O5S
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:491.56
  • hCAIX/XII-IN-8

    CAS:
    <p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>
    Formula:C16H13Cl2N5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.28
  • Carbonic anhydrase inhibitor 12

    CAS:
    <p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>
    Formula:C27H22BrN5O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.53
  • N-Desethyl Brinzolamide oxalate

    CAS:
    <p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>
    Formula:C12H19N3O9S3
    Color and Shape:Solid
    Molecular weight:445.49
  • COX-2-IN-30

    CAS:
    <p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>
    Formula:C17H16N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.41
  • hCAIX-IN-16

    CAS:
    <p>hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.</p>
    Formula:C20H20N8O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.49
  • ALP/Carbonic anhydrase-IN-1

    CAS:
    <p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>
    Formula:C15H16N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:224.3
  • CAXII-IN-1

    CAS:
    <p>CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.</p>
    Formula:C13H7Cl2NO3S
    Color and Shape:Solid
    Molecular weight:328.17
  • hCAIX-IN-15

    CAS:
    <p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>
    Formula:C18H14FN7O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.41
  • CAII-IN-2


    <p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>
    Formula:C18H19BrN4S
    Color and Shape:Solid
    Molecular weight:403.34
  • Carbonic anhydrase inhibitor 5


    <p>Potent hCA inhibitor: targets hCA II, IX &amp; XII with IC50s of 42.9, 47.6, &amp; 6.7 nM respectively.</p>
    Formula:C24H20ClN3O3S
    Color and Shape:Solid
    Molecular weight:465.95
  • Carbonic anhydrase inhibitor 9


    <p>Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.</p>
    Formula:C22H20BrN5O4S
    Color and Shape:Solid
    Molecular weight:530.39
  • hCAII-IN-5

    CAS:
    <p>hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].</p>
    Formula:C29H18N2O7
    Color and Shape:Solid
    Molecular weight:506.46
  • hCAII-IN-3


    <p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>
    Formula:C17H21N3O3S
    Color and Shape:Solid
    Molecular weight:347.43
  • Valerate sodium

    CAS:
    <p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>
    Formula:C5H9NaO2
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:124.11