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Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.

Found 177 products of "Carbonic Anhydrase"

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  • Carbonic anhydrase inhibitor 16

    CAS:
    <p>Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.</p>
    Formula:C14H10N2O4S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:302.31
  • CAII-IN-1


    <p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>
    Formula:C19H21FN4S
    Color and Shape:Solid
    Molecular weight:356.46
  • Sulclamide

    CAS:
    <p>Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].</p>
    Formula:C7H7ClN2O3S
    Color and Shape:Solid
    Molecular weight:234.66
  • hCAVII/IX-IN-1

    CAS:
    <p>hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.</p>
    Formula:C7H7N3O2S2
    Color and Shape:Solid
    Molecular weight:229.279
  • CAII-IN-3


    <p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>
    Formula:C18H18F2N4S
    Color and Shape:Solid
    Molecular weight:360.42
  • β-Glucuronidase/hCAII-IN-2


    <p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>
    Formula:C31H23NO8
    Color and Shape:Solid
    Molecular weight:537.52
  • Carbonic anhydrase inhibitor 19

    CAS:
    <p>Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.</p>
    Formula:C23H25N3O6S2
    Molecular weight:503.59
  • Carbonic anhydrase inhibitor 2

    CAS:
    <p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>
    Formula:C12H16N4O6S
    Color and Shape:Solid
    Molecular weight:344.34
  • α-Glucosidase-IN-63

    CAS:
    <p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>
    Formula:C16H12FN3O3S2
    Color and Shape:Solid
    Molecular weight:377.41
  • hCAII-IN-4

    CAS:
    <p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>
    Formula:C31H23NO9
    Color and Shape:Solid
    Molecular weight:553.52
  • Carbonic anhydrase inhibitor 8


    <p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>
    Formula:C20H25N3O4S
    Color and Shape:Solid
    Molecular weight:403.5
  • Carbonic anhydrase inhibitor 3


    <p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>
    Formula:C15H17N3O3S
    Color and Shape:Solid
    Molecular weight:319.38
  • hCA XII/II/IX-IN-1


    <p>hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.</p>
    Formula:C25H34N4O7S
    Color and Shape:Solid
    Molecular weight:534.63
  • Carbonic anhydrase inhibitor 10


    <p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>
    Formula:C14H17N5O3S
    Color and Shape:Solid
    Molecular weight:335.38
  • β-Glucuronidase/hCAII-IN-1

    CAS:
    <p>β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50</p>
    Formula:C30H21NO9
    Color and Shape:Solid
    Molecular weight:539.49
  • NSC 828467


    <p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>
    Formula:C21H19N9O2S
    Color and Shape:Solid
    Molecular weight:461.5
  • hCA VB-IN-1


    <p>hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].</p>
    Formula:C9H13N3O4S
    Color and Shape:Solid
    Molecular weight:259.28