ROR
Retinoic Acid-Related Orphan Receptors (RORs) are nuclear receptors that regulate various physiological processes, including circadian rhythm, immune response, and metabolism. ROR inhibitors are of interest in the study of autoimmune diseases, metabolic disorders, and cancer, as they can modulate gene expression and influence cellular functions. At CymitQuimica, we offer ROR inhibitors to support your research in immunology, endocrinology, and oncology.
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ML 209
CAS:1334526-14-5
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM …
Formula:
C25H31NO6
Purity:
99.65%
Color and Shape:
Liquid
Molecular weight:
441.52
Ref: TM-T37587
| 1mg | 92.00 € | ||
| 5mg | 210.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 449.00 € | ||
| 50mg | 652.00 € | ||
| 100mg | 895.00 € | ||
| 500mg | 1,786.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
AZD-0284
CAS:2101291-07-8
AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment …
Formula:
C21H18F6N2O5S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
524.43
Ref: TM-T14369
| 1mg | 58.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
RORγt Inverse agonist 8
CAS:2079892-79-6
RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with …
Formula:
C26H33N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
475.59
Ref: TM-T12754
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Methyl-3β-hydroxycholenate
CAS:20231-57-6
Methyl-3β-hydroxycholenate (Methyl 3beta-hydroxychol-5-enoate) is a modulator of RORγ.
Formula:
C25H40O3
Purity:
98.78%
Color and Shape:
Solid
Molecular weight:
388.58
Ref: TM-T11923
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
XY101
CAS:2349368-16-5
XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 …
Formula:
C25H20F7NO4S
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
563.48
Ref: TM-T13362
| 1mg | 87.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 867.00 € | ||
| 500mg | 1,691.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
TMP780
CAS:1422053-03-9
TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target …
Formula:
C31H30N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
494.58
Ref: TM-T13172
| 25mg | 1,539.00 € | ||
| 50mg | 2,005.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Monday 5 May 2025
3-Oxo-5β-cholanoic acid
CAS:1553-56-6
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation …
Formula:
C24H38O3
Purity:
98.01% - 99.77%
Color and Shape:
Solid
Molecular weight:
374.56
Ref: TM-T13502
| 10mg | 48.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 89.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 5 May 2025
RORγt inverse agonist 14
CAS:2672496-70-5
RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an …
Formula:
C26H26F8N2O6S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
678.61
Ref: TM-T72252
| 5mg | 1,681.00 € | ||
| 50mg | 3,402.00 € | ||
| 100mg | 4,655.00 € |
Estimated delivery in United States, on Monday 5 May 2025
FM26
CAS:2407981-35-3
FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.
Formula:
C22H15ClF3N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
461.82
Ref: TM-T11308
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Monday 5 May 2025
RORγt Inverse agonist 6
CAS:1887161-80-9
RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can …
Formula:
C28H29ClN6O5
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
565.02
Ref: TM-T12753
| 1mg | 62.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 562.00 € | ||
| 200mg | 743.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Monday 5 May 2025
RORγt inverse agonist 32
CAS:2301159-96-4
RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory …
Formula:
C24H28F3NO5S
Color and Shape:
Liquid
Molecular weight:
499.54
Ref: TM-T200887
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
TAK-828F
CAS:1854901-94-2
TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.
Formula:
C28H32FN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
509.57
Ref: TM-T13067
| 25mg | 3,012.00 € | ||
| 50mg | 3,971.00 € | ||
| 100mg | 5,510.00 € |
Estimated delivery in United States, on Monday 2 Jun 2025
Vimirogant
CAS:1802706-04-2
Vimirogant is a RORγ inhibitor (Ki: <100 nM).
Formula:
C27H35F3N4O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
552.65
Ref: TM-T16787
| 25mg | 2,157.00 € | ||
| 50mg | 2,832.00 € | ||
| 100mg | 3,800.00 € |
Estimated delivery in United States, on Monday 2 Jun 2025
A-9758
CAS:2055271-22-0
A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.
Formula:
C25H23Cl2F3N2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
527.36
Ref: TM-T10210
| 25mg | 2,442.00 € | ||
| 50mg | 3,212.00 € | ||
| 100mg | 4,370.00 € |
Estimated delivery in United States, on Monday 2 Jun 2025
