ROR
Retinoic Acid-Related Orphan Receptors (RORs) are nuclear receptors that regulate various physiological processes, including circadian rhythm, immune response, and metabolism. ROR inhibitors are of interest in the study of autoimmune diseases, metabolic disorders, and cancer, as they can modulate gene expression and influence cellular functions. At CymitQuimica, we offer ROR inhibitors to support your research in immunology, endocrinology, and oncology.
Found 49 products for "ROR".
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
S18-000003
CAS:S18-000003: Oral retinoic acid receptor gamma-t inhibitor, IC50 29 nM, reduces IL-17 production.Formula:C26H25F3N2O4SPurity:99.24% - 99.31%Color and Shape:White SolidMolecular weight:518.548GSK805
CAS:GSK805 is a potent, orally bioavailable and CNS-penetrant RORγt inhibitor.Cost-effective and quality-assured.Formula:C23H18Cl2F3NO4SPurity:98% - ≥95%Color and Shape:White SolidMolecular weight:532.36Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.65% - 99.95%Color and Shape:Yellow SolidMolecular weight:402.3946SR3335
CAS:SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).Formula:C13H9F6NO3S2Purity:99.77%Color and Shape:SolidMolecular weight:405.336SR1078
CAS:SR1078 is an agonist of retinoic acid receptor-related orphan receptor (ROR)α/γ.Formula:C17H10F9NO2Purity:99.58%Color and Shape:SolidMolecular weight:431.25ROR1-IN-2
ROR1-IN-2 (compound 9I) is a potent and selective inhibitor of ROR1. It exhibits antiproliferative activity in various cancer cell lines and significantly inhibits tumor growth in vivo.Formula:C30H27N3O4Color and Shape:SolidMolecular weight:493.20016RORγt Inverse agonist 8
CAS:RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with an IC50 of 19 nM).Formula:C26H33N7O2Purity:98%Color and Shape:SolidMolecular weight:475.59XY101
CAS:XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).Formula:C25H20F7NO4SPurity:99.83%Color and Shape:SolidMolecular weight:563.484TF-S14
CAS:TF-S14 is an inverse agonist of RORγt. It functions by binding to RORγt and inhibiting its activity, leading to a reduction in Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22. TF-S14 is applicable in research related to autoimmune diseases and allogeneic transplant rejection.Formula:C22H27N3O2SColor and Shape:SolidMolecular weight:397.53MRL-871
CAS:MRL-871 is a selective RORγt allosteric inhibitor, reducing IL-17a mRNA production in EL4 cells, interacting with PPARgamma in partial agonistic binding modes.Formula:C22H12ClF3N2O3Purity:99.66%Color and Shape:SolidMolecular weight:444.79GNE-0946
CAS:GNE-0946 is an effective and selective RORγ/RORc/NR1F3 antagonist (inverse agonist) with an EC50 of 4 nM in HEK-293 cells. autoimmune disease research.Formula:C22H12ClF3N2O4Purity:98.11%Color and Shape:SolidMolecular weight:460.79AZD-0284
CAS:AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].Formula:C21H18F6N2O5SPurity:99.82%Color and Shape:SolidMolecular weight:524.433SR2211
CAS:SR2211 is a specific modulator and an inverse agonist of RORγ(IC50 = 320 nM, Ki = 105 nM).Formula:C26H24F7N3OPurity:98.75%Color and Shape:White SolidMolecular weight:527.48ML 209
CAS:ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcriptionFormula:C25H31NO6Purity:99.87%Color and Shape:SolidMolecular weight:441.5167GNE-6468
CAS:GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).Formula:C23H16ClN3O4Purity:98.68% - 99.73%Color and Shape:SolidMolecular weight:433.844FM26
CAS:FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.Formula:C22H15ClF3N3O3Purity:98%Color and Shape:SolidMolecular weight:461.82RORγt Inverse agonist 6
CAS:RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.Formula:C28H29ClN6O5Purity:99.52%Color and Shape:SolidMolecular weight:565.02RORγt inverse agonist 14
CAS:RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity.Formula:C26H26F8N2O6S2Purity:98%Color and Shape:SolidMolecular weight:678.613-Oxo-5β-cholanoic acid
CAS:3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directlyFormula:C24H38O3Purity:98.01% - 99.86%Color and Shape:White SolidMolecular weight:374.5567TMP780
CAS:TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.Formula:C31H30N2O4Purity:98%Color and Shape:SolidMolecular weight:494.5809
