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FAAH

FAAH

Fatty Acid Amide Hydrolase (FAAH) is an enzyme that breaks down fatty acid amides, including endocannabinoids like anandamide. These compounds are involved in the regulation of pain, mood, appetite, and memory. Inhibition of FAAH can increase the levels of these signaling molecules, offering potential therapeutic benefits for pain, anxiety, and neurodegenerative diseases. At CymitQuimica, we offer a selection of FAAH inhibitors to support your research in neuroscience, pain management, and endocannabinoid signaling.

Found 63 products of "FAAH"

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  • FAAH/cPLA2α-IN-1

    CAS:
    <p>FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (</p>
    Formula:C19H26N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:390.43
  • OMDM-5

    CAS:
    <p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>
    Formula:C26H44N2O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:432.64
  • JP104

    CAS:
    <p>JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].</p>
    Formula:C25H30N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.52
  • 3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone

    CAS:
    <p>3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone (compound 45), having a pI50 of 5.89, shows promise as an inhibitor of fatty acid amide hydrolase (FAAH). Despite its activity, it demonstrates a lack of affinity for cannabinoid receptors CB(1) and CB(2) [1].</p>
    Formula:C25H32N2OS
    Color and Shape:Solid
    Molecular weight:408.6
  • FAAH inhibitor 2

    CAS:
    <p>FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].</p>
    Formula:C24H40N2O2
    Color and Shape:Solid
    Molecular weight:388.59
  • Sob-AM2

    CAS:
    <p>Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).</p>
    Formula:C21H27NO3
    Color and Shape:Solid
    Molecular weight:341.44
  • MK-3168 (12C)

    CAS:
    <p>MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.</p>
    Formula:C21H21ClN4OS
    Color and Shape:Solid
    Molecular weight:412.94
  • FAAH/MAGL-IN-1


    <p>FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH &amp; MAGL with IC50 of 31 &amp; 29 nM, useful in neuropathic pain research.</p>
    Formula:C15H9Cl2N3O3
    Color and Shape:Solid
    Molecular weight:350.16
  • FAAH/MAGL-IN-2

    CAS:
    <p>FAAH/MAGL-IN-2: potent, reversible, oral FAAH &amp; MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.</p>
    Formula:C15H13Cl2N3O3S
    Color and Shape:Solid
    Molecular weight:386.25
  • FAAH/MAGL-IN-3


    <p>FAAH/MAGL-IN-3 irreversibly inhibits FAAH (IC50: 179 nM) &amp; MAGL (IC50: 759 nM) with low PAMPA permeability.</p>
    Formula:C21H25N3O6S
    Color and Shape:Solid
    Molecular weight:447.5
  • AZ513

    CAS:
    <p>AZ513 is a reversible FAAH inhibitor, exhibiting an IC50 of 551 nM for human FAAH and 27 nM for rat FAAH. It inhibits the hydrolysis of arachidonoyl ethanolamide in HEK293 cells transfected with human FAAH, with an IC50 of 360 nM.</p>
    Formula:C14H9Cl2N3O
    Color and Shape:Solid
    Molecular weight:306.147
  • Dual FAAH/sEH-IN-1

    CAS:
    <p>Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.</p>
    Formula:C25H22ClN3O3S2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:512.04
  • TC-F 2

    CAS:
    <p>TC-F 2 is a FAAH inhibitor.</p>
    Formula:C26H25N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.51

    Ref: TM-T23432

    1mg
    Discontinued
    Discontinued product