PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 170 products of "PPAR"
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K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Formula:C18H25Cl3O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:379.75BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Formula:C22H16ClN3O4Purity:99.73%Color and Shape:SoildMolecular weight:421.83Ref: TM-T67933
1mg38.00€5mg84.00€10mg119.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)93.00€Linotroban
CAS:Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Formula:C14H15NO5S2Purity:97.95% - >99.99%Color and Shape:SolidMolecular weight:341.4Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Formula:C23H20N2O4SPurity:99.76%Color and Shape:SolidMolecular weight:420.48LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Formula:C21H24ClNO4SPurity:97.15%Color and Shape:SolidMolecular weight:421.94KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Formula:C30H33F3N2O8S2Purity:99.61%Color and Shape:SolidMolecular weight:670.72PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFormula:C19H12F4O2SPurity:98%Color and Shape:SolidMolecular weight:380.36U-46619
CAS:U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFormula:C26H28ClF3N4O3SPurity:98%Color and Shape:SolidMolecular weight:569.04PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Formula:C20H25NO6SPurity:98%Color and Shape:SolidMolecular weight:407.48CRX000227
CAS:CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Formula:C24H20N2O4S2Purity:98%Color and Shape:SolidMolecular weight:464.56Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Formula:C27H26N4O4SPurity:99.41% - 99.53%Color and Shape:SolidMolecular weight:502.58Ref: TM-T15581
1mg70.00€5mg149.00€10mg230.00€25mg374.00€50mg532.00€100mg713.00€500mgTo inquire1mL*10mM (DMSO)178.00€Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Formula:C25H25NO5Purity:97.46% - 98.56%Color and Shape:SolidMolecular weight:419.47PPARγ phosphorylation inhibitor 1
CAS:PPARγ phosphorylation inhibitor 1, PPARγ agonist (IC50=24 nM), inhibits CDK5-mediated Ser273 phosphorylation, antidiabetic activity.Formula:C22H14Cl2N2O4Purity:99.86%Color and Shape:SolidMolecular weight:441.26SR 11023
CAS:SR 11023, an orally active PPAR γ antagonist, exhibits an IC 50 value of 109 nM and is significant in diabetes research [1].Formula:C33H36N2O3Color and Shape:SolidMolecular weight:508.65Anti-NASH agent 2
CAS:Anti-NASH agent 2 (compound 21) is an inhibitor of neolipogenesis activity and α-SMA gene expression. It improves hepatic steatosis, edema, inflammatory infiltration, and liver fibrosis in NASH mouse models.
Formula:C32H51N3O2Color and Shape:SolidMolecular weight:509.766PPARγ agonist 17
CAS:PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.Formula:C48H63NO7Color and Shape:SolidMolecular weight:766.016PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Formula:C26H21NO7S3SeColor and Shape:SolidMolecular weight:634.6
