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Dehydrogenase

Dehydrogenase

Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.

Found 267 products of "Dehydrogenase"

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  • AZD 4017

    CAS:
    <p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>
    Formula:C22H33N3O3S
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:419.58
  • 15-PGDH-IN-1

    CAS:
    <p>15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.</p>
    Formula:C24H22N4O2
    Color and Shape:Solid
    Molecular weight:398.46
  • GSK321

    CAS:
    <p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>
    Formula:C28H28FN5O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:501.55
  • CHK-336

    CAS:
    <p>CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 &lt;1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria</p>
    Formula:C24H20F2N4O4S2
    Color and Shape:Solid
    Molecular weight:530.57
  • 15-PGDH-IN-2

    CAS:
    <p>15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].</p>
    Formula:C16H13NO3S2
    Color and Shape:Solid
    Molecular weight:331.41
  • hDHODH-IN-1

    CAS:
    <p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>
    Formula:C17H14N2O2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:278.31
  • YG1702

    CAS:
    <p>YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.</p>
    Formula:C23H30N2O7S
    Color and Shape:Solid
    Molecular weight:478.56
  • PF-915275

    CAS:
    <p>PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.</p>
    Formula:C18H14N4O2S
    Purity:99.58% - 99.61%
    Color and Shape:Solid
    Molecular weight:350.39
  • Anticancer agent 121

    CAS:
    <p>Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].</p>
    Formula:C19H18N2O3S
    Color and Shape:Solid
    Molecular weight:354.42
  • MK-0736

    CAS:
    <p>MK-0736 is a potent and selective 11β-HSD-1 inhibitor.</p>
    Formula:C23H30F3N3O2S
    Color and Shape:Solid
    Molecular weight:469.56
  • HSD17B13-IN-3

    CAS:
    <p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>
    Formula:C22H21NO6S2
    Color and Shape:Solid
    Molecular weight:459.54
  • Tetrahydro-11-dehydrocorticosterone

    CAS:
    <p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>
    Formula:C21H32O4
    Color and Shape:Solid
    Molecular weight:348.48
  • DHODH-IN-22

    CAS:
    <p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>
    Formula:C21H21ClF4N6O5
    Color and Shape:Solid
    Molecular weight:548.88
  • DHODH-IN-14

    CAS:
    <p>DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.</p>
    Formula:C15H7F4N3O3
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:353.23
  • IDH889

    CAS:
    <p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>
    Formula:C23H25FN6O2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:436.48
  • Anticancer agent 122

    CAS:
    <p>Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in</p>
    Formula:C18H15ClN2O2S
    Color and Shape:Solid
    Molecular weight:358.84
  • KB-74935

    CAS:
    <p>KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.</p>
    Formula:C19H18ClF4N3O3S
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:479.88
  • ALDH2 modulator 1

    CAS:
    <p>ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.</p>
    Formula:C18H18ClFN2O3
    Purity:99.68%
    Color and Shape:Soild
    Molecular weight:364.8
  • CB29

    CAS:
    <p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>
    Formula:C15H15N3O5S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:349.36
  • BI-3231

    CAS:
    <p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>
    Formula:C16H14F2N4O3S
    Purity:98.2%
    Color and Shape:Solid
    Molecular weight:380.37