Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 300 products of "Dehydrogenase"
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hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formula:C19H16N2O2Purity:98%Color and Shape:SolidMolecular weight:304.349Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Formula:C15H13F3N2O2Purity:99.86%Color and Shape:SolidMolecular weight:310.27P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Formula:C17H16N2O3Purity:99.92%Color and Shape:SolidMolecular weight:296.32DHODH-IN-21
CAS:DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.Formula:C20H19ClF4N6O4Color and Shape:SolidMolecular weight:518.85DHODH-IN-17
CAS:DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.Formula:C12H9ClN2O2Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:248.67Ref: TM-T60364
5mg43.00€10mg65.00€25mg119.00€50mg172.00€100mg255.00€200mg356.00€1mL*10mM (DMSO)46.00€CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Formula:C22H30N6O4Color and Shape:SolidMolecular weight:442.5111β-HSD1-IN-9
CAS:11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.Formula:C13H9F3N2OColor and Shape:SolidMolecular weight:266.22ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Formula:C20H21N3O2Purity:98%Color and Shape:SolidMolecular weight:335.4Oxycinchophen
CAS:Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.Formula:C16H11NO3Purity:98%Color and Shape:SolidMolecular weight:265.26GW648495
CAS:GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.Formula:C16H13N5Purity:98%Color and Shape:SolidMolecular weight:275.31BVT-116429
CAS:BVT-116429 is an inhibitor of 11β-HSD1.Formula:C13H12F4N2OSPurity:98%Color and Shape:SolidMolecular weight:320.31p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Formula:C11H14O2Purity:99.87%Color and Shape:White To Light Beige PowderMolecular weight:178.23ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Formula:C11H14N2O3Color and Shape:SolidMolecular weight:222.24GA11
CAS:GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.Formula:C19H14N2Purity:98%Color and Shape:SolidMolecular weight:270.33AGI-14100
CAS:AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
Formula:C29H22ClF4N5O3Purity:99.91%Color and Shape:SolidMolecular weight:599.96DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Formula:C21H24N4O2Purity:99.87%Color and Shape:SolidMolecular weight:364.44TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Formula:C26H32N2O6Color and Shape:SolidMolecular weight:468.54AZD8329
CAS:AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.Formula:C25H31N3O3Purity:99.31%Color and Shape:SolidMolecular weight:421.53Ref: TM-T14383
1mg87.00€5mg178.00€10mg295.00€25mg612.00€50mg897.00€100mg1,558.00€1mL*10mM (DMSO)203.00€ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Formula:C19H16ClF3N4O2Color and Shape:SolidMolecular weight:424.8DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84RS6212
CAS:RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.
Formula:C20H22N4O3SColor and Shape:SolidMolecular weight:398.48ML-148
CAS:ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).Formula:C20H21N3OPurity:99.88%Color and Shape:SolidMolecular weight:319.4Ref: TM-T38163
1mg60.00€5mg165.00€10mg254.00€25mg459.00€50mg658.00€100mg935.00€200mg1,283.00€1mL*10mM (DMSO)188.00€BRD9185
CAS:BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Formula:C23H21F6N3O2Purity:98%Color and Shape:SolidMolecular weight:485.42ALDH1A1-IN-2
CAS:ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesityFormula:C25H23ClN4O3SPurity:99.48%Color and Shape:SolidMolecular weight:494.99UCK2 Inhibitor-2
CAS:UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.Formula:C28H23N3O4SPurity:98.76% - 99.25%Color and Shape:SolidMolecular weight:497.5711β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFormula:C16H10F3NO2Color and Shape:SolidMolecular weight:305.25AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Formula:C14H22N2OSPurity:98%Color and Shape:SolidMolecular weight:266.4EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Formula:C13H15NO2Color and Shape:SolidMolecular weight:217.26Chlorisondamine diiodide
CAS:Chlorisondamine diiodide is a selective nAChR antagonist and ganglionic blocker that persistently antagonizes partial central effects of nicotine.Formula:C14H20Cl4I2N2Purity:99.97%Color and Shape:SolidMolecular weight:611.94Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Formula:C17H14N4OSPurity:98%Color and Shape:SolidMolecular weight:322.3811β-HSD1-IN-1
CAS:11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.Formula:C18H14ClF4N3OPurity:99.84%Color and Shape:SolidMolecular weight:399.77Ref: TM-T10160
1mg50.00€5mg105.00€10mg155.00€25mg224.00€50mg314.00€100mg427.00€1mL*10mM (DMSO)112.00€DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Formula:C17H13ClN2O2Purity:99.78%Color and Shape:SolidMolecular weight:312.75Ref: TM-T11030
1mg109.00€2mg163.00€5mg241.00€10mg354.00€25mg532.00€50mg745.00€100mg1,018.00€500mgTo inquire1mL*10mM (DMSO)235.00€hDHODH-IN-11
CAS:hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46IMB-XMA0038
CAS:IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Formula:C11H10N4O6Purity:98.94% - 99.96%Color and Shape:SolidMolecular weight:294.22INCB13739
CAS:INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.Formula:C28H25N3O4Purity:99.32%Color and Shape:SoildMolecular weight:467.52Ref: TM-T60203
1mg94.00€5mg215.00€10mg344.00€25mg683.00€50mg945.00€100mg1,251.00€200mg1,701.00€1mL*10mM (DMSO)227.00€MEDS433
CAS:MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.Formula:C20H11F4N3O2Color and Shape:SolidMolecular weight:401.3111β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.86DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Color and Shape:SolidMolecular weight:394.51DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Formula:C17H12Cl2N2O2Purity:99.34%Color and Shape:SolidMolecular weight:347.2Ref: TM-T11027
1mg109.00€2mg163.00€5mg243.00€10mg355.00€25mg532.00€50mg750.00€100mg1,009.00€500mg2,035.00€1mL*10mM (DMSO)248.00€Nitrefazole
CAS:Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.Formula:C10H8N4O4Color and Shape:SolidMolecular weight:248.19CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Formula:C19H15FN4OSColor and Shape:SolidMolecular weight:366.41DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formula:C10H9N3O2Purity:99.53%Color and Shape:SolidMolecular weight:203.2Ref: TM-T11021
1mg73.00€5mg149.00€10mg213.00€25mg319.00€50mg447.00€100mg610.00€200mg823.00€1mL*10mM (DMSO)122.00€11β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFormula:C19H27ClN2O3SPurity:99.89%Color and Shape:SolidMolecular weight:398.95673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27NCT-506
CAS:NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).Formula:C25H23FN4O3SPurity:98%Color and Shape:SolidMolecular weight:478.54DHODH-IN-1
CAS:DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.Formula:C21H20F3N3O2Purity:99.76%Color and Shape:SolidMolecular weight:403.4SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Formula:C30H39Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:544.56DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Color and Shape:SolidMolecular weight:479.47
