Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 267 products of "Dehydrogenase"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Oxycinchophen
CAS:<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Formula:C16H11NO3Purity:98%Color and Shape:SolidMolecular weight:265.26GW648495
CAS:<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Formula:C16H13N5Purity:98%Color and Shape:SolidMolecular weight:275.31BVT-116429
CAS:<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Formula:C13H12F4N2OSPurity:98%Color and Shape:SolidMolecular weight:320.31GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formula:C19H14N2Purity:98%Color and Shape:SolidMolecular weight:270.33RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formula:C20H22N4O3SColor and Shape:SolidMolecular weight:398.48RORγt/DHODH-IN-2
CAS:<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Formula:C25H30N4OSColor and Shape:SolidMolecular weight:434.6UCK2 Inhibitor-2
CAS:<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Formula:C28H23N3O4SPurity:98.76% - 99.25%Color and Shape:SolidMolecular weight:497.57DHODH-IN-20
CAS:<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Formula:C24H25F4N3O3Color and Shape:SolidMolecular weight:479.47hDHODH-IN-4
CAS:<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Formula:C21H24N4O2Purity:99.87%Color and Shape:SolidMolecular weight:364.44ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Formula:C31H36F3N5O4Color and Shape:SolidMolecular weight:599.64AZD8329
CAS:<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Formula:C25H31N3O3Purity:99.31%Color and Shape:SolidMolecular weight:421.53KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formula:C12H11NO3SPurity:99.88%Color and Shape:SolidMolecular weight:249.29ALDH1A1-IN-2
CAS:<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Formula:C25H23ClN4O3SPurity:99.48%Color and Shape:SolidMolecular weight:494.99Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formula:C15H13F3N2O2Purity:99.86%Color and Shape:SolidMolecular weight:310.27hDHODH-IN-9
CAS:<p>hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.</p>Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.4RV01
CAS:<p>RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.</p>Formula:C17H13NO2Purity:99.93%Color and Shape:SolidMolecular weight:263.29hDHODH-IN-3
CAS:<p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>Formula:C18H19BrN4O2Purity:99.871%Color and Shape:SolidMolecular weight:403.27Genz-669178
CAS:<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Formula:C17H14N4OSPurity:98%Color and Shape:SolidMolecular weight:322.38EN40
CAS:<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Formula:C13H15NO2Color and Shape:SolidMolecular weight:217.26DHODH-IN-13
CAS:<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Formula:C10H6F3N3O3Purity:99.66%Color and Shape:SolidMolecular weight:273.17DHODH-IN-15
CAS:<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Formula:C15H11N3O3Purity:99.8%Color and Shape:SolidMolecular weight:281.27DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Formula:C12H9ClN2O2Purity:99.41% - 99.52%Color and Shape:SolidMolecular weight:248.67DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formula:C21H20F3N3O2Purity:99.76%Color and Shape:SolidMolecular weight:403.4hDHODH-IN-5
CAS:<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Formula:C21H21F3N2O2Purity:99.55%Color and Shape:SolidMolecular weight:390.4p-Valerylphenol
CAS:<p>p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.</p>Formula:C11H14O2Purity:99.87%Color and Shape:White To Light Beige PowderMolecular weight:178.23M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Formula:C17H16N2O3Purity:99.43%Color and Shape:SolidMolecular weight:296.32Manitimus
CAS:<p>Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.</p>Formula:C15H11F3N2O2Purity:99.75% - 99.75%Color and Shape:SolidMolecular weight:308.26Metapramine
CAS:<p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>Formula:C16H18N2Purity:99.03% - 99.67%Color and Shape:SolidMolecular weight:238.3311β-HSD1-IN-1
CAS:<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formula:C18H14ClF4N3OPurity:99.84%Color and Shape:SolidMolecular weight:399.77DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formula:C17H12Cl2N2O2Purity:99.34%Color and Shape:SolidMolecular weight:347.2DHODH-IN-8
CAS:<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Formula:C17H13ClN2O2Purity:99.78%Color and Shape:SolidMolecular weight:312.7511β-HSD1-IN-12
CAS:<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Formula:C19H27ClN2O3SPurity:99.68%Color and Shape:SolidMolecular weight:398.95Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Formula:C10H8N4O4Color and Shape:SolidMolecular weight:248.1911β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.86CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Formula:C19H15FN4OSColor and Shape:SolidMolecular weight:366.41MEDS433
CAS:<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formula:C20H11F4N3O2Color and Shape:SolidMolecular weight:401.31hDHODH-IN-11
CAS:<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46DHODH-IN-12
CAS:<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Formula:C10H9N3O2Purity:99.53%Color and Shape:SolidMolecular weight:203.2AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Formula:C14H22N2OSPurity:98%Color and Shape:SolidMolecular weight:266.411β-HSD1-IN-10
CAS:<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formula:C16H10F3NO2Color and Shape:SolidMolecular weight:305.25673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84ASP3662
CAS:<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formula:C19H16ClF3N4O2Color and Shape:SolidMolecular weight:424.8TM-1
CAS:<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formula:C26H32N2O6Color and Shape:SolidMolecular weight:468.54DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75ALDH3A1-IN-2
CAS:<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formula:C11H14N2O3Color and Shape:SolidMolecular weight:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColor and Shape:SolidMolecular weight:266.22DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formula:C20H19ClF4N6O4Color and Shape:SolidMolecular weight:518.85BRD9185
CAS:<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formula:C23H21F6N3O2Purity:98%Color and Shape:SolidMolecular weight:485.42P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3
