Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 267 products of "Dehydrogenase"
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ML-148
CAS:<p>ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).</p>Formula:C20H21N3OPurity:99.88%Color and Shape:SolidMolecular weight:319.4DS18561882
CAS:<p>DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.</p>Formula:C28H31F3N4O6SPurity:98.19% - >99.99%Color and Shape:SolidMolecular weight:608.63Olorofim
CAS:<p>Olorofim（F-901318）is a new selective antifungal compound that inhibits Aspergillus fumigatus DHODH (IC50: 44 nM). Cost-effective and quality-assured.</p>Formula:C28H27FN6O2Purity:99.28%Color and Shape:SolidMolecular weight:498.55Qc1
CAS:<p>Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.</p>Formula:C23H16F3N3O2SPurity:99.75%Color and Shape:SolidMolecular weight:455.45CPS-11
CAS:<p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>Formula:C14H12N2O5Purity:99.8% - 99.98%Color and Shape:SolidMolecular weight:288.26ALDH1A3-IN-2
CAS:<p>ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.</p>Formula:C13H17NOPurity:99.84%Color and Shape:SolidMolecular weight:203.28PHGDH-IN-3
CAS:<p>PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.</p>Formula:C24H18FN3O4S2Purity:97.24% - 98.55%Color and Shape:SolidMolecular weight:495.55HSD-016
CAS:<p>HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.</p>Formula:C21H21F7N2O3SPurity:99.40% - >99.99%Color and Shape:SolidMolecular weight:514.46CM037
CAS:<p>CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminate</p>Formula:C21H25N3O3S2Purity:99.34%Color and Shape:SolidMolecular weight:431.57IDH2R140Q-IN-2
CAS:<p>IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).</p>Formula:C21H18F6N6OPurity:99.92%Color and Shape:SolidMolecular weight:484.4IGP-1
CAS:<p>iGP-1 is a cell-permeable mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH) inhibitor.</p>Formula:C17H15N3O3Purity:99.12% - 99.15%Color and Shape:SolidMolecular weight:309.32PKUMDL-WQ-2101
CAS:<p>PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.</p>Formula:C14H11N3O6Purity:99.57%Color and Shape:SolidMolecular weight:317.25hDHODH-IN-7
CAS:<p>hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.</p>Formula:C21H23FN4OPurity:99.87%Color and Shape:SolidMolecular weight:366.43BMS-823778
CAS:<p>BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.</p>Formula:C18H18ClN3OPurity:99.39% - 99.75%Color and Shape:SolidMolecular weight:327.81IMPDH2-IN-2
CAS:<p>IMPDH2-IN-2 is an IMPDH inhibitor with antimicrobial activity and potential anti-tuberculosis activity for the study of inflammation and immune dysfunction.</p>Formula:C21H15Cl2N3O3Purity:99.02%Color and Shape:SolidMolecular weight:428.27G6PD activator AG1
CAS:<p>G6PD activator AG1 is a G6PD agonist that promotes G6PD oligomerization to a catalytically competent form.</p>Formula:C24H30N4S2Purity:98.38% - 99.51%Color and Shape:SolidMolecular weight:438.65DSM421
CAS:<p>DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown</p>Formula:C14H11F5N6Purity:98.23% - 99.82%Color and Shape:SolidMolecular weight:358.27HSD17B13-IN-2
CAS:<p>HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1</p>Formula:C21H23F2NO4Color and Shape:SolidMolecular weight:391.41α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Formula:C12H12N2O2Color and Shape:SolidMolecular weight:216.24IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Formula:C26H22N4OPurity:98%Color and Shape:SolidMolecular weight:406.48AZD 4017
CAS:<p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>Formula:C22H33N3O3SPurity:99.61%Color and Shape:SolidMolecular weight:419.5815-PGDH-IN-1
CAS:<p>15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.</p>Formula:C24H22N4O2Color and Shape:SolidMolecular weight:398.46GSK321
CAS:<p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>Formula:C28H28FN5O3Purity:99.73%Color and Shape:SolidMolecular weight:501.55CHK-336
CAS:<p>CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria</p>Formula:C24H20F2N4O4S2Color and Shape:SolidMolecular weight:530.5715-PGDH-IN-2
CAS:<p>15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].</p>Formula:C16H13NO3S2Color and Shape:SolidMolecular weight:331.41hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Formula:C17H14N2O2Purity:99.97%Color and Shape:SolidMolecular weight:278.31YG1702
CAS:<p>YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.</p>Formula:C23H30N2O7SColor and Shape:SolidMolecular weight:478.56PF-915275
CAS:<p>PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.</p>Formula:C18H14N4O2SPurity:99.58% - 99.61%Color and Shape:SolidMolecular weight:350.39Anticancer agent 121
CAS:<p>Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].</p>Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42MK-0736
CAS:<p>MK-0736 is a potent and selective 11β-HSD-1 inhibitor.</p>Formula:C23H30F3N3O2SColor and Shape:SolidMolecular weight:469.56HSD17B13-IN-3
CAS:<p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>Formula:C22H21NO6S2Color and Shape:SolidMolecular weight:459.54Tetrahydro-11-dehydrocorticosterone
CAS:<p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>Formula:C21H32O4Color and Shape:SolidMolecular weight:348.48DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Formula:C21H21ClF4N6O5Color and Shape:SolidMolecular weight:548.88DHODH-IN-14
CAS:<p>DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.</p>Formula:C15H7F4N3O3Purity:99.81%Color and Shape:SolidMolecular weight:353.23IDH889
CAS:<p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>Formula:C23H25FN6O2Purity:≥98%Color and Shape:SolidMolecular weight:436.48Anticancer agent 122
CAS:<p>Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in</p>Formula:C18H15ClN2O2SColor and Shape:SolidMolecular weight:358.84KB-74935
CAS:<p>KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.</p>Formula:C19H18ClF4N3O3SPurity:99.4%Color and Shape:SolidMolecular weight:479.88ALDH2 modulator 1
CAS:<p>ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.</p>Formula:C18H18ClFN2O3Purity:99.68%Color and Shape:SoildMolecular weight:364.8CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Formula:C15H15N3O5SPurity:99.36%Color and Shape:SolidMolecular weight:349.36BI-3231
CAS:<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Formula:C16H14F2N4O3SPurity:98.2%Color and Shape:SolidMolecular weight:380.377-Hydroxy-4-phenylcoumarin
CAS:<p>7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.</p>Formula:C15H10O3Color and Shape:SolidMolecular weight:238.238T-3764518
CAS:<p>T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).</p>Formula:C20H17F6N5O2Purity:98%Color and Shape:SolidMolecular weight:473.37DSM705 hydrochloride
<p>DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.</p>Formula:C19H20ClF3N6OColor and Shape:SolidMolecular weight:440.85FXR/HSD17B13 modulator 1
CAS:<p>FXR/HSD17B13 modulator 1 (compound 6) is an effective modulator of FXR/HSD17B13, playing a significant role in studies related to metabolic dysfunction-associated steatohepatitis (MASH).</p>Formula:C26H19Cl2NO4Color and Shape:SolidMolecular weight:480.339RORγt/DHODH-IN-3
<p>RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 has</p>Formula:C24H26ClF6N3O3SColor and Shape:SolidMolecular weight:585.99PHGDH-IN-2
<p>PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.</p>Formula:C22H20N4O3SColor and Shape:SolidMolecular weight:420.48BI-4916
CAS:<p>BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.</p>Formula:C23H24Cl2N2O6SPurity:98.55%Color and Shape:SolidMolecular weight:527.42PDHK-IN-4
<p>PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.</p>Formula:C24H25N5O3Color and Shape:SolidMolecular weight:431.49PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32BRD7539
CAS:<p>BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.</p>Formula:C23H22FN3O2Purity:98%Color and Shape:SolidMolecular weight:391.44
