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Dehydrogenase

Dehydrogenase

Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.

Found 267 products of "Dehydrogenase"

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  • CymitQuimica logo
    Targetmol
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    PDHK-IN-5

    <p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) &amp; PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>
    Formula:C30H31N5O2
    Color and Shape:Solid
    Molecular weight:493.6

    Ref: TM-T63327

  • Deamino-NAD sodium
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    Deamino-NAD sodium

    CAS:
    <p>Deamino-NAD sodium, a structural analog of NAD+, serves as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH) in glycolysis. It exhibits a Km of 2300 pm and a Kd of 112 pm.</p>
    Formula:C21H25N6NaO15P2
    Color and Shape:Solid
    Molecular weight:686.39

    Ref: TM-T200588

  • Etamicastat
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    Etamicastat

    CAS:
    <p>Etamicastat can be used in the research of cardiovascular diseases.</p>
    Formula:C14H15F2N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:311.35

    Ref: TM-T11238

  • 11β-HSD2-IN-2
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    11β-HSD2-IN-2

    CAS:
    <p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>
    Formula:C22H21NO2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:331.41

    Ref: TM-T85382

  • GSK864
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    GSK864

    CAS:
    <p>GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).</p>
    Formula:C30H31FN6O4
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:558.6

    Ref: TM-T15442

  • MDH1/2-IN-1
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    MDH1/2-IN-1

    CAS:
    <p>MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.</p>
    Formula:C25H33NO4
    Color and Shape:Solid
    Molecular weight:411.534

    Ref: TM-T206508

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    AXKO-0046

    <p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>
    Formula:C25H33N3
    Color and Shape:Solid
    Molecular weight:375.55

    Ref: TM-T61539

  • CymitQuimica logo
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    Indoluidin E

    <p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>
    Formula:C28H30N4O2
    Color and Shape:Solid
    Molecular weight:454.56

    Ref: TM-T62802

  • LDHA-IN-5
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    LDHA-IN-5

    CAS:
    <p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>
    Formula:C27H22FN7O6S3
    Color and Shape:Solid
    Molecular weight:655.7

    Ref: TM-T73222

  • CymitQuimica logo
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    hDHODH-IN-10

    <p>hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.</p>
    Formula:C21H15ClF4N2O4
    Color and Shape:Solid
    Molecular weight:470.8

    Ref: TM-T63037

  • RORγt/DHODH-IN-1
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    RORγt/DHODH-IN-1

    CAS:
    <p>RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant</p>
    Formula:C24H26ClF6N3O3S
    Color and Shape:Solid
    Molecular weight:585.99

    Ref: TM-T64145

  • Etamicastat hydrochloride
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    Etamicastat hydrochloride

    CAS:
    <p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>
    Formula:C14H16ClF2N3OS
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:347.81

    Ref: TM-T11238L

  • CP-642931
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    CP-642931

    CAS:
    <p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>
    Formula:C17H25N7O
    Purity:99.67% - >99.99%
    Color and Shape:Solid
    Molecular weight:343.43

    Ref: TM-T31070

  • PS10
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    PS10

    CAS:
    <p>PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.</p>
    Formula:C14H13NO6S
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:323.32

    Ref: TM-T12566

    1mg
    Discontinued
    2mg
    Discontinued
    Discontinued product
  • GNE-140 racemate
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    GNE-140 racemate

    CAS:
    <p>GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.</p>
    Formula:C25H23ClN2O3S2
    Color and Shape:Solid
    Molecular weight:499.04

    Ref: TM-T13450L

    1mg
    Discontinued
    Discontinued product
  • (S)-GNE-140
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    (S)-GNE-140

    CAS:
    <p>(S)-GNE-140 is the less active enantiomer of GNE-140.</p>
    Formula:C25H23ClN2O3S2
    Color and Shape:Solid
    Molecular weight:499.05

    Ref: TM-T13450

    1mg
    Discontinued
    2mg
    Discontinued
    Discontinued product
  • 11β-HSD1-IN-8
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    11β-HSD1-IN-8

    CAS:
    <p>11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.</p>
    Formula:C10H8F3NO3
    Color and Shape:Solid
    Molecular weight:247.173

    Ref: TM-T65743

    ne
    Discontinued
    Discontinued product