Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 132 products for "Lipoxygenase".
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Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColor and Shape:SolidMolecular weight:635.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:White SolidMolecular weight:393.5Ref: TM-T16503
5mg50.00€1mL*10mM (DMSO)55.00€10mg79.00€25mg146.00€50mg245.00€100mg355.00€500mg772.00€Lonapalene
CAS:Lonapalene is a topically effective inhibitor of 5-lipoxygenase.Formula:C16H15ClO6Purity:98.67% - 99.33%Color and Shape:SolidMolecular weight:338.74Ref: TM-T16802
1mg100.00€2mg160.00€5mg290.00€1mL*10mM (DMSO)318.00€10mg424.00€25mg642.00€50mg858.00€100mg1,153.00€200mg1,558.00€Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Formula:C14H20O2Purity:98.11% - 98.95%Color and Shape:SolidMolecular weight:220.315-LOX-IN-1
CAS:5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.Formula:C20H18N2O2SPurity:97.09%Color and Shape:SolidMolecular weight:350.43A-69412
CAS:A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.Formula:C7H10N2O3Purity:99.54%Color and Shape:SolidMolecular weight:170.17Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72Ref: TM-T19679
1mg192.00€1mL*10mM (DMSO)444.00€5mg447.00€10mg670.00€25mg982.00€50mg1,243.00€100mg1,575.00€L 670630
CAS:L 670630 is a potent and orally active 5-lipoxygenase inhibitor.Formula:C25H26O3Purity:98%Color and Shape:SolidMolecular weight:374.47AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Formula:C15H13FN2O4Purity:98%Color and Shape:SolidMolecular weight:304.2715(S)-HEDE
CAS:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.5A 78773
CAS:A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.Formula:C15H13FN2O4Color and Shape:SolidMolecular weight:304.275,6-dehydro Arachidonic Acid
CAS:5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.Formula:C20H30O2Color and Shape:SolidMolecular weight:302.45h15-LOX-2 inhibitor 1
CAS:Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].Formula:C17H13F3N2SPurity:98%Color and Shape:SolidMolecular weight:334.36CMI-392
CAS:CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).Formula:C31H37ClN2O8SPurity:98%Color and Shape:SolidMolecular weight:633.15TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Formula:C29H36N2O7Color and Shape:SolidMolecular weight:524.615-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Formula:C23H28N4O2SColor and Shape:SolidMolecular weight:424.56MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Formula:C14H15ClN2OPurity:99.84%Color and Shape:SolidMolecular weight:262.7317(S)-HpDHA
CAS:17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49(2E,9Z)-Octadeca-2,9-dienoic acid
CAS:(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, is utilized in the study of lipoxygenase-dependent metabolism [1].Formula:C18H32O2Color and Shape:SolidMolecular weight:280.45Setileuton
CAS:Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.Formula:C22H17F4N3O4Purity:98.85% - 99.35%Color and Shape:SolidMolecular weight:463.38Ref: TM-T34624
1mg177.00€5mg432.00€1mL*10mM (DMSO)537.00€10mg587.00€25mg892.00€50mg1,198.00€100mg1,575.00€200mg2,133.00€PXS-6302 hydrochloride
CAS:PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3Formula:C10H11ClF3NO2SPurity:99.98%Color and Shape:SolidMolecular weight:301.71CCT365623
CAS:CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.Formula:C18H17NO4S3Purity:97.29% - 97.63%Color and Shape:White SolidMolecular weight:407.53Ref: TM-T26969
1mg86.00€5mg180.00€1mL*10mM (DMSO)225.00€10mg245.00€25mg374.00€50mg504.00€100mg662.00€200mg875.00€L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Formula:C36H35ClN6OSPurity:98%Color and Shape:SolidMolecular weight:635.22WY-50295
CAS:WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. In rat whole blood leukocytes, WY-50295 inhibits LTB4 formation with an IC50 of 40 μM and an oral ED50 of 18 mg/kg. WY-50295 is applicable for research into asthma and other leukotriene-dependent conditions.Formula:C23H19NO3Color and Shape:SolidMolecular weight:357.40h15-LOX-2 inhibitor 3
CAS:Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.Formula:C22H13N5O3Color and Shape:SolidMolecular weight:395.375-LOX/MAOs-IN-1
CAS:Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.Formula:C18H18N2O2Color and Shape:SolidMolecular weight:294.35Lobaric acid
CAS:Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.Formula:C25H28O8Color and Shape:SolidMolecular weight:456.48ALOX15-IN-1
ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.Formula:C24H31N3O5SColor and Shape:SolidMolecular weight:473.59AZD 4407
CAS:AZD 4407 is a potent inhibitor of 5-lipoxygenase.Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5Resolvin E2
CAS:RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.Formula:C20H30O4Color and Shape:SolidMolecular weight:334.45ALOX15-IN-2
CAS:ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Formula:C23H29N3O4SPurity:99.98%Color and Shape:SolidMolecular weight:443.56Ref: TM-T62606
1mg46.00€5mg90.00€1mL*10mM (DMSO)100.00€10mg160.00€25mg313.00€50mg537.00€100mg767.00€500mg1,558.00€
