Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,957 products)
- Antibiotic(920 products)
- Antifection(23 products)
- DHFR(33 products)
- DNA/RNA Synthesis(708 products)
- HBV(176 products)
- HIV Protease(449 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
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Found 5842 products of "Microbiology/Virology"
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HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.452-Acetyl-2-decarboxamidotetracycline
CAS:<p>2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.</p>Formula:C23H25NO8Color and Shape:SolidMolecular weight:443.45TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Formula:C24H34N4O2SColor and Shape:SolidMolecular weight:442.62Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Formula:C27H40N3O5PSColor and Shape:SolidMolecular weight:549.66Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formula:C17H10ClNO5Color and Shape:SolidMolecular weight:343.72PfPKG-IN-1
<p>PfPKG-IN-1, an imidazole-based inhibitor, targets the Plasmodium falciparum cyclic guanosine monophosphate-dependent protein kinase (PfPKG).</p>Formula:C24H22ClN7OSColor and Shape:SolidMolecular weight:492Lavendomycin
CAS:<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formula:C29H50N10O8Color and Shape:SolidMolecular weight:666.77Antimalarial agent 2
<p>Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.</p>Formula:C27H25N3O5Color and Shape:SolidMolecular weight:471.5SPR7
<p>SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).</p>Formula:C30H32ClN3O3Color and Shape:SolidMolecular weight:518.05BRD-4592
CAS:<p>BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.</p>Formula:C17H15FN2OColor and Shape:SolidMolecular weight:282.312HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Formula:C7H4N2O4S2Color and Shape:SolidMolecular weight:244.248Antibacterial agent 261
CAS:<p>Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).</p>Formula:C18H24N4O3S2Color and Shape:SolidMolecular weight:408.538BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Formula:C25H30ClFN2OColor and Shape:SolidMolecular weight:428.97Antitumor agent-74
<p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5Quorum sensing-IN-9
CAS:<p>Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.</p>Formula:C9H10OS2Color and Shape:SolidMolecular weight:198.305Pibrozelesin
CAS:<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Formula:C32H36BrN5O8Color and Shape:SolidMolecular weight:698.56Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Formula:C14H11N3O4SColor and Shape:SolidMolecular weight:317.32ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Color and Shape:SolidHIV-1 inhibitor-41
<p>HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.</p>Formula:C16H15F2N3OSColor and Shape:SolidMolecular weight:335.37N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Formula:C17H19N5O5Color and Shape:SolidMolecular weight:373.363(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS:<p>(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.</p>Formula:C26H36F3NO4SColor and Shape:SolidMolecular weight:515.629MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Formula:C13H6Cl2N2O3Color and Shape:SolidMolecular weight:309.104PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217HBV-IN-12
CAS:<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Formula:C23H27NO8Color and Shape:SolidMolecular weight:445.46Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Formula:C20H18N2OColor and Shape:SolidMolecular weight:302.37AN-12-H5
CAS:<p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>Formula:C24H23N3O4S3Color and Shape:SolidMolecular weight:513.65G092
<p>G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.</p>Formula:C23H20Cl2N2O3Color and Shape:SolidMolecular weight:443.32MraY-IN-2
<p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>Formula:C16H23N3O9Color and Shape:SolidMolecular weight:401.37Adafosbuvir
CAS:<p>Adafosbuvir has antiviral activity.</p>Formula:C22H29FN3O10PColor and Shape:SolidMolecular weight:545.457Cap-dependent endonuclease-IN-6
CAS:<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formula:C23H21N3O3SColor and Shape:SolidMolecular weight:419.5Gln-AMS TFA
<p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>Formula:C17H23F3N8O10SColor and Shape:SolidMolecular weight:588.47Zorubicin
CAS:<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>Formula:C34H35N3O10Color and Shape:SolidMolecular weight:645.66AK-968-11563024
CAS:<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formula:C18H13I2N9O5Color and Shape:SolidMolecular weight:689.162HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53Antibacterial agent 259
CAS:<p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>Formula:C7H6ClN3O2SColor and Shape:SolidMolecular weight:231.659Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Formula:C30H24FN3O7SColor and Shape:SolidMolecular weight:589.59Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Formula:C23H22BrN3O5Color and Shape:SolidMolecular weight:500.34UNC0638 hydrate
CAS:<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Formula:C30H49N5O3Color and Shape:SolidMolecular weight:527.74ZINC4497834
CAS:<p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>Formula:C18H19N5O3SColor and Shape:SolidMolecular weight:385.44PLpro-IN-7
CAS:<p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>Formula:C30H34ClN7OColor and Shape:SolidMolecular weight:544.09FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formula:C15H11ClN4O4S2Color and Shape:SolidMolecular weight:410.86Purine phosphoribosyltransferase-IN-2
<p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17FPI-1465
CAS:<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formula:C11H18N4O7SColor and Shape:SolidMolecular weight:350.35Antibacterial agent 262
CAS:<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formula:C17H18F2N6O4S3Color and Shape:SolidMolecular weight:504.554RAD51-IN-7
CAS:<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formula:C25H31N5O4S2Color and Shape:SolidMolecular weight:529.67Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formula:C13H10BrNO4SColor and Shape:SolidMolecular weight:356.192ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Formula:C21H34N4O4SPurity:98.22% - 99.60%Color and Shape:SolidMolecular weight:438.58CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formula:C17H16N2O7Color and Shape:SolidMolecular weight:360.318Palmitanilide
CAS:<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formula:C22H37NOColor and Shape:SolidMolecular weight:331.535Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formula:C21H29FN2Color and Shape:SolidMolecular weight:328.47Ciluprevir
CAS:<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93PolQi1
CAS:<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Formula:C18H14ClF5N4O2Purity:98.97%Color and Shape:SolidMolecular weight:448.77Amicoumacin A
CAS:<p>Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.</p>Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46EFdA-TP tetrasodium
CAS:<p>EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.</p>Formula:C12H11FN5Na4O12P3Purity:98%Color and Shape:SolidMolecular weight:621.12Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Formula:C21H24ClN7Color and Shape:SolidMolecular weight:409.928-Hydroxyerythromycin A
CAS:<p>8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.</p>Formula:C37H67NO14Color and Shape:SolidMolecular weight:749.926BMT-052
CAS:<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formula:C30H17D9F4N6O5Purity:98%Color and Shape:SolidMolecular weight:635.61Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5YKL-04-085
CAS:<p>YKL-04-085 inhibits viral translation effectively, with strong antiviral action at much lower doses than those affecting host-cell growth.</p>Formula:C30H29N5O2Color and Shape:SolidMolecular weight:491.6NBTIs-IN-4
<p>NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.</p>Formula:C22H24FN5O5SColor and Shape:SolidMolecular weight:489.52Kikumycin A
CAS:<p>Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.</p>Formula:C13H17N7O2Color and Shape:SolidMolecular weight:303.32MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formula:C23H18Cl2FNO3Color and Shape:SolidMolecular weight:446.3Finafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formula:C20H19FN4O4Color and Shape:SolidMolecular weight:398.39Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formula:C22H18N2O2Color and Shape:SolidMolecular weight:342.39G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formula:C24H19Cl2FO3Color and Shape:SolidMolecular weight:445.31GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.243-Deazaguanosine
CAS:<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Formula:C25H31F3N12O10S2Color and Shape:SolidMolecular weight:780.71DRF-8417
CAS:<p>DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.</p>Formula:C15H17N3O5SColor and Shape:SolidMolecular weight:351.38Cyclophilin inhibitor 1
CAS:<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Formula:C24H24FN5O7SColor and Shape:SolidMolecular weight:545.54TAN-1057C
CAS:<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Formula:C13H25N9O3Color and Shape:SolidMolecular weight:355.4PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Formula:C28H27ClN4O4Color and Shape:SolidMolecular weight:518.99Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurity:98%Color and Shape:SolidMolecular weight:718.04BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurity:98%Color and Shape:SolidMolecular weight:286.24NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formula:C14H9IN2O3SColor and Shape:SolidMolecular weight:412.2MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formula:C23H19Cl2NO3Color and Shape:SolidMolecular weight:428.31Plevitrexed
CAS:<p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53RAD51-IN-8
<p>RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.</p>Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Formula:C27H21N5O2SColor and Shape:SolidMolecular weight:479.55Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Formula:C8H12N2S2Color and Shape:SolidMolecular weight:200.32Xeruborbactam
CAS:<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Formula:C10H8BFO4Purity:98%Color and Shape:SolidMolecular weight:221.98Ladirubicin
CAS:<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Formula:C29H31NO11SColor and Shape:SolidMolecular weight:601.62CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formula:C10H9BrN4O2SColor and Shape:SolidMolecular weight:329.172'-(2-Nitrobenzyl)-ATP
CAS:<p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>Formula:C17H21N6O15P3Color and Shape:SolidMolecular weight:642.30Antibacterial agent 266
CAS:<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formula:C13H11N3OColor and Shape:SolidMolecular weight:225.246Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Color and Shape:SolidMolecular weight:468.453VPC-80051
CAS:<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formula:C16H13F2N3OColor and Shape:SolidMolecular weight:301.291KKL-40
CAS:<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Formula:C16H9F4N3O2Color and Shape:SolidMolecular weight:351.255Jun13296
CAS:<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Formula:C30H34N6OColor and Shape:SolidMolecular weight:494.631Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formula:C7H14N3NaO8SColor and Shape:SolidMolecular weight:323.26Teslexivir
CAS:<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formula:C35H36BrN3O4Purity:98%Color and Shape:SolidMolecular weight:642.58MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Formula:C15H10BrN5O2SColor and Shape:SolidMolecular weight:404.24L-697639
CAS:<p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>Formula:C18H21N3O2Color and Shape:SolidMolecular weight:311.38BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61
