Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(3,389 products)
- Antibiotic(941 products)
- Antifection(27 products)
- DHFR(30 products)
- DNA/RNA Synthesis(803 products)
- HBV(185 products)
- HIV Protease(507 products)
- HSV(99 products)
- Integrase(2 products)
- Ribosome(6 products)
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Found 6402 products of "Microbiology/Virology"
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Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55MTH1 activator-1
CAS:MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.Formula:C29H23F3N4O2Color and Shape:SolidMolecular weight:516.514MI-1851
CAS:MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.Formula:C34H53N15O6Color and Shape:SolidMolecular weight:767.88KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Formula:C12H10BN3O2SColor and Shape:SolidMolecular weight:271.1PKZ18
CAS:PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.Formula:C22H26N2O3SPurity:98.08%Color and Shape:SolidMolecular weight:398.5183HKT-IN-1
CAS:3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.Formula:C12H11BrN2O3Color and Shape:SolidMolecular weight:311.131MsbA-IN-3
MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).Formula:C24H22Cl2N2O4SColor and Shape:SolidMolecular weight:505.41Tuberculosis inhibitor 4
TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.Formula:C23H26N2O3SColor and Shape:SolidMolecular weight:410.533-Deazaguanosine
CAS:3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25ZK-806450
CAS:ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.Formula:C31H31N5OColor and Shape:SolidMolecular weight:489.611Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67PLP_Snyder530
PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formula:C16H11F2N3Color and Shape:SolidMolecular weight:283.28trans-Clopenthixol
CAS:Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.Formula:C22H25ClN2OSColor and Shape:SolidMolecular weight:400.965LolCDE-IN-2
CAS:LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Formula:C22H17N5OPurity:98%Color and Shape:SolidMolecular weight:367.40Anti-MRSA agent 27
CAS:Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.Formula:C15H10F3N3OSColor and Shape:SolidMolecular weight:337.32DRF-8417
CAS:DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.Formula:C15H17N3O5SColor and Shape:SolidMolecular weight:351.38A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66VNI
CAS:VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.Formula:C26H19Cl2N5O2Color and Shape:SolidMolecular weight:504.37β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Formula:C21H17Cl3O7Color and Shape:SolidMolecular weight:487.71PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formula:C22H29N5O2Color and Shape:SolidMolecular weight:395.5KL-50
CAS:KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.Formula:C7H7FN6O2Color and Shape:SolidMolecular weight:226.17HldA/E-IN-1
CAS:HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.Formula:C8H17FO13P2Color and Shape:SolidMolecular weight:402.16Laninamivir trifluoroacetate
CAS:Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.Formula:C15H23F3N4O9Purity:98%Color and Shape:SolidMolecular weight:460.363SARS-CoV-2-IN-99
CAS:SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.Formula:C20H16Br2NO4PColor and Shape:SolidMolecular weight:525.13Epiderstatin
CAS:Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.Formula:C15H20N2O4Color and Shape:SolidMolecular weight:292.33Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26Cefempidone
CAS:Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.Formula:C22H21N7O6S2Molecular weight:543.58Pks13-TE inhibitor 4
CAS:Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.Formula:C26H25N5O6Molecular weight:503.51GC-78-HCl
CAS:GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.Formula:C25H25Cl3N4O4Molecular weight:551.85Cetefloxacin
CAS:Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.Formula:C20H16F3N3O3Molecular weight:403.35SARS-CoV-2 Mpro-IN-31
CAS:SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.Formula:C31H34Cl2N4O7Color and Shape:SolidMolecular weight:645.53GRL-190-21
CAS:GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].
Formula:C24H34F3N5O4Color and Shape:SolidMolecular weight:513.55LasR antagonist 1
CAS:LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Formula:C20H15F3N2O3Color and Shape:SolidMolecular weight:388.34SARS-CoV-2 Mpro-IN-32
CAS:SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.Formula:C34H32Cl2N4O9Color and Shape:SolidMolecular weight:711.54Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColor and Shape:SolidMolecular weight:584.32SARS-CoV-2 Mpro-IN-28
CAS:SARS-CoV-2 Mpro-IN-28 (Compound 1K) is an inhibitor of SARS-CoV-2 Mpro, exhibiting an EC50 of 24 μM.Formula:C14H17NO3SeColor and Shape:SolidMolecular weight:326.25Polθ-IN-5
CAS:Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.Formula:C23H18ClF2N7O3SColor and Shape:SolidMolecular weight:545.95TBAJ-5307
CAS:TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Formula:C30H35BrN4O6Color and Shape:SolidMolecular weight:627.53NNRT-IN-5
CAS:NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.Formula:C27H22N8Color and Shape:SolidMolecular weight:458.52SARS-CoV-IN-6
CAS:SARS-CoV-IN-6 (Compound 17) acts as an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, demonstrating an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. This compound reduces the cytopathic effects of single-round infectious particles (SRIP) infected with SARS-CoV-1 and SARS-CoV-2 replicons and inhibits the expression of SARS-CoVN proteins. The EC50 values for SRIP based on SARS-CoV-1 and SARS-CoV-2 replicons are 0.12 µM and 1.47 µM, respectively.Formula:C25H29N5O3Color and Shape:SolidMolecular weight:447.53(E)-Cefodizime
CAS:(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.Formula:C20H20N6O7S4Color and Shape:SolidMolecular weight:584.669Eravacycline
CAS:Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formula:C27H31FN4O8Purity:97.46%Color and Shape:SolidMolecular weight:558.56SARS-CoV-2 Mpro-IN-44
CAS:SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.Formula:C29H19Cl2FN8O4SColor and Shape:SolidMolecular weight:665.48Omaciclovir
CAS:Omaciclovir (ABT-091) is a herpesvirus herpesvirus replication inhibitor with antiviral activity that is used in the study of herpesvirus infections.Formula:C10H15N5O3Purity:99.46% - 99.46%Color and Shape:SolidMolecular weight:253.26Saroaspidin B
CAS:Saroaspidin B is a dimeric form of a biphenyl triphenol, characterized as an antibiotic compound.Formula:C25H32O8Color and Shape:SolidMolecular weight:460.52APE1-IN-3
CAS:APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.Formula:C17H16O4Color and Shape:SolidMolecular weight:284.312-Acetyl-2-decarboxamidotetracycline
CAS:2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.
Formula:C23H25NO8Color and Shape:SolidMolecular weight:443.45Etofamide
CAS:Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.Formula:C19H20Cl2N2O5Color and Shape:SolidMolecular weight:427.28Saptomycin E
CAS:Saptomycin E is an antitumor antibiotic.Formula:C33H35NO9Color and Shape:SolidMolecular weight:589.632-Bromo-2'-methoxyacetophenone
CAS:2-Bromo-2'-methoxyacetophenone acts as an irreversible inhibitor of MurA, effectively inhibiting MurA in E. coli with an IC50 of 0.38 μM. This compound helps inhibit bacterial cell wall synthesis, making it useful in antimicrobial research.Formula:C9H9BrO2Molecular weight:229.07PROTAC eDHFR Degrader-2
CAS:PROTACeDHFR Degrader-2 (compound 7b) is an effective degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), capable of reliably degrading eDHFR-tagged proteins.Formula:C34H40N8O9Molecular weight:704.73AYK004-C1
CAS:AYK004-C1 is a TLR agonist used in the formulation of immunological adjuvants.Formula:C35H58F3N7O3Molecular weight:681.88HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Formula:C37H37ClN2O6S2Color and Shape:SolidMolecular weight:705.28Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formula:C9H20N2O8Color and Shape:SolidMolecular weight:284.26Doxazosin impurity 12
CAS:Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.
Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217PCNA-IN-1
CAS:PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065Piperacillin hydrate
CAS:Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Formula:C23H29N5O8SColor and Shape:SolidMolecular weight:535.57H2S scavenger 1 (triflate)
H2S scavenger 1 triflate (Compound 7b) serves as a selective H2S depleting agent, particularly against glutathione. This compound impedes the formation of bacterial biofilms and enhances the sensitivity of Staphylococcus aureus to gentamicin or photosensitizers by depleting H2S.Formula:C13H16F3N5O6SMolecular weight:427.36Anti-ToCV agent 1
Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.Formula:C22H19FN2O5SColor and Shape:SolidMolecular weight:442.46Kikumycin A
CAS:Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.Formula:C13H17N7O2Color and Shape:SolidMolecular weight:303.324-Chloropyridine
CAS:4-Chloropyridine acts as an inhibitor of Nicotinamide N-methyltransferase (NNMT). Serving as a substrate for NNMT, this compound enhances the electrophilicity at the C4 position through methylation of the pyridine nitrogen. This modification facilitates an aromatic nucleophilic substitution reaction with the non-catalytic cysteine (C159) in NNMT, ultimately leading to suicidal activity inhibition of the enzyme. 4-Chloropyridine is a promising candidate for the development of activity-based probes targeting NNMT functions.Formula:C5H4ClNColor and Shape:SolidMolecular weight:113.55Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formula:C23H24N6OColor and Shape:SolidMolecular weight:400.48Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Color and Shape:SolidMolecular weight:443.41HC2210
CAS:HC2210 exhibits antibacterial effects against Mycobacterium abscessus (Mab) with an EC50 of 0.72 µM. It modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is applicable for studies on Mab infections.Formula:C17H18N4O9Color and Shape:SolidMolecular weight:422.35DPC 684
CAS:DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.Formula:C35H48FN5O5SColor and Shape:SolidMolecular weight:669.85Pyriofenone
CAS:Pyriofenone (IKF-309) is an aryl phenyl ketone fungicide predominantly used to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. It exhibits moderate efficacy against rice blast disease. Pyriofenone functions through prevention, residue activity, treatment, rainfastness, translaminar action, and fumigation.Formula:C18H20ClNO5Color and Shape:SolidMolecular weight:365.81L-Tyrosyl-L-glutamic acid
CAS:L-Tyrosyl-L-glutamic acid acts as an inhibitor of the amino acid permease GAP1.Formula:C14H18N2O6Color and Shape:SolidMolecular weight:310.3RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Color and Shape:SolidMolecular weight:763.11FIZ1 degrader 1
CAS:FIZ1 degrader 1 (compound 1) is an IMiD-based molecular glue degrader targeting FIZ1.Formula:C16H15N3O4Color and Shape:SolidMolecular weight:313.316-N-Hydroxylaminopurine
CAS:6-N-Hydroxylaminopurine is a base analog with mutagenic activity.Formula:C5H5N5OMolecular weight:151.13GTSE1-IN-1
CAS:GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.Formula:C21H24FN7Color and Shape:SolidMolecular weight:393.46ZHSI-1
CAS:ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that blocks EV71/CVA16 replication and virus-induced pyroptosis linked to viral pathogenesis. It effectively prevents EV71 infection in neonatal and young mice in animal models and can be used to study viral infections such as hand, foot, and mouth disease (HFMD) [1].Formula:C17H19N5Color and Shape:SolidMolecular weight:293.3717,17-Ethylendioxyandrost-5-en-3β-ol
CAS:17,17-Ethylendioxyandrost-5-en-3β-ol, with an EC 50 of 629 μM, acts as an inhibitor of HSV-1. This compound is applicable in research studies focusing on viral infections.Formula:C21H32O3Color and Shape:SolidMolecular weight:332.48CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Formula:C21H17ClF3N3O3SColor and Shape:SolidMolecular weight:483.89Clavicoronic acid
CAS:Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.Formula:C15H18O4Color and Shape:SolidMolecular weight:262.3D-CS319
CAS:D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formula:C7H11NO2S3Color and Shape:SolidMolecular weight:237.36Mer-NF5003F
CAS:Mer-NF5003F (Stachybotrydial; F 1839M) is a sesquiterpene isolated from Stachybotrys, effective in inhibiting avian myeloblastosis virus (AMV) protease with an IC50 of 7.8 μM. It also inhibits sialyltransferases ST6N, ST3O, and ST3N with IC50 values of 0.61, 6.7, and 10 μg/mL, respectively, and fucosyltransferase with an IC50 of 11.3 μg/mL. Additionally, Mer-NF5003F exhibits in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multi-drug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).Formula:C23H30O5Molecular weight:386.48HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColor and Shape:SolidMolecular weight:443.43(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formula:C17H37N7O3Color and Shape:SolidMolecular weight:387.52Ibafloxacine
CAS:Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect againstFormula:C15H14FNO3Purity:97.67%Color and Shape:SolidMolecular weight:275.27MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Color and Shape:SolidMolecular weight:373.18HBV-IN-48
CAS:HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.Formula:C22H15F4N3O3Color and Shape:SolidMolecular weight:445.37DXR-IN-3
CAS:DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.Formula:C10H12Cl2NO5PSColor and Shape:SolidMolecular weight:360.15MK-8876
CAS:MK-8876 is an Inhibitor of HCV NS5B Site D.Formula:C32H24F2N4O5SPurity:98%Color and Shape:SolidMolecular weight:614.62Triazophos
CAS:Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.Formula:C12H16N3O3PSColor and Shape:SolidMolecular weight:313.31Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Isopyrazam
CAS:Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Formula:C20H23F2N3OColor and Shape:SolidMolecular weight:359.41GSK_WRN4
CAS:GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer researchFormula:C16H20N2O4SPurity:99.95%Color and Shape:SolidMolecular weight:336.41Anti-infective agent 10
CAS:Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.Formula:C26H25N3O7SColor and Shape:SolidMolecular weight:523.56Antimalarial agent 44
Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.Formula:C37H37N5O7Color and Shape:SolidMolecular weight:663.72MLEB-22043
MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.Formula:C25H25N9O11S2Color and Shape:SolidMolecular weight:691.652,5-Di-tert-butyl-1,4-benzoquinone
CAS:2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formula:C14H20O2Color and Shape:SolidMolecular weight:220.31SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formula:C30H37Cl2N5O3Color and Shape:SolidMolecular weight:586.55Cefamandole lithium
CAS:Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formula:C18H17LiN6O5S2Color and Shape:SolidMolecular weight:468.44Cilastatin ammonium salt
CAS:Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formula:C16H29N3O5SColor and Shape:SolidMolecular weight:375.48Antibacterial agent 66
Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.Formula:C17H10ClF6N3O2SColor and Shape:SolidMolecular weight:469.79(Rac)-Plevitrexed
CAS:(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53PFK-IN-1
CAS:PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formula:C18H15Cl2N3O4SColor and Shape:SolidMolecular weight:440.3Saussureamine C
CAS:Saussureamine C is an inhibitor of H274Y and N294S mutants.Formula:C19H26N2O5Color and Shape:SolidMolecular weight:362.42
