Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(3,423 products)
- Antibiotic(945 products)
- Antifection(27 products)
- DHFR(30 products)
- DNA/RNA Synthesis(808 products)
- HBV(186 products)
- HIV Protease(507 products)
- HSV(99 products)
- Integrase(2 products)
- Ribosome(5 products)
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Found 6442 products of "Microbiology/Virology"
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Antitumor agent-74
Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Formula:C24H34N4O2SColor and Shape:SolidMolecular weight:442.62Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formula:C29H18BrN3O2Color and Shape:SolidMolecular weight:520.386Ipronidazole
CAS:Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.Formula:C7H11N3O2Color and Shape:SolidMolecular weight:169.18Homer
CAS:Homer is a probe designed to target WD repeat domain 5 (WDR5). In MV4-11 cells, Homer induces the degradation of WDR5 with a half-maximal degradation concentration (DC50) of 53 nM. At a concentration of 1 µM, Homer decreases the protein levels of WDR5 in MV4-11 cells without affecting the mRNA levels that encode WDR5.Formula:C52H60F3N9O7SColor and Shape:SolidMolecular weight:1012.15NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Formula:C18H16F4N4O2SColor and Shape:SolidMolecular weight:428.40VV261
CAS:VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.Formula:C28H34FN3O11Color and Shape:SolidMolecular weight:607.58MLEB-22043
MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.Formula:C25H25N9O11S2Color and Shape:SolidMolecular weight:691.65Plevitrexed
CAS:Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formula:C15H13N3O4SColor and Shape:SolidMolecular weight:331.35Isazofos
CAS:Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.Formula:C9H17ClN3O3PSColor and Shape:SolidMolecular weight:313.74Penethamate hydriodide
CAS:Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.Formula:C22H32IN3O4SColor and Shape:SolidMolecular weight:561.477bc1 Complex-IN-1
CAS:Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Formula:C16H22N6O5S2Color and Shape:SolidMolecular weight:442.513Palmitanilide
CAS:Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formula:C22H37NOColor and Shape:SolidMolecular weight:331.535RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Color and Shape:SolidMolecular weight:763.11HC2210
CAS:HC2210 exhibits antibacterial effects against Mycobacterium abscessus (Mab) with an EC50 of 0.72 µM. It modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is applicable for studies on Mab infections.Formula:C17H18N4O9Color and Shape:SolidMolecular weight:422.35Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFormula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45Antimicrobial agent-38
CAS:Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.Formula:C14H11N3O4SColor and Shape:SolidMolecular weight:317.32RNase L ligand 3
CAS:RNase L ligand 3 is an RNase L ligand employed in the synthesis of F3-PEG8-RiboTAC.Formula:C27H27N3OSColor and Shape:SolidMolecular weight:441.59HCV-IN-38
Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.Formula:C22H24ClF3N4O4Color and Shape:SolidMolecular weight:500.9Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColor and Shape:SolidMolecular weight:584.32SARS-CoV-2 Mpro-IN-32
CAS:SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.Formula:C34H32Cl2N4O9Color and Shape:SolidMolecular weight:711.54Cap-dependent endonuclease-IN-5
CAS:Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Formula:C27H21F2N3O4S2Color and Shape:SolidMolecular weight:553.60Cefclidin
CAS:Cefclidin (Cefclidine) is a cephalosporin compound.Formula:C21H26N8O6S2Color and Shape:SolidMolecular weight:550.611Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Formula:C27H21N5O2SColor and Shape:SolidMolecular weight:479.55CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Formula:C21H17ClF3N3O3SColor and Shape:SolidMolecular weight:483.89Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5MI-1851
CAS:MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.Formula:C34H53N15O6Color and Shape:SolidMolecular weight:767.88BMT-052
CAS:BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formula:C30H17D9F4N6O5Purity:98%Color and Shape:SolidMolecular weight:635.61LpxH-IN-2
CAS:LpxH-IN-2 (compound 014), a potent inhibitor of LpxH, exhibits antibacterial activity against E. coli.Formula:C27H33ClF2N6O4SColor and Shape:SolidMolecular weight:611.10DHFS-IN-1
CAS:DHFS-IN-1 (Compound 3) is an inhibitor of dihydrofolate synthetase (DHFS) with an IC50 of 2.6 μM. It is applicable for research into infectious diseases related to bacterial folate synthesis.Formula:C16H16N8O2Color and Shape:SolidMolecular weight:352.35EBOV-IN-10
CAS:EBOV-IN-10 is an orally active inhibitor of the Ebola virus (EBOV) with an EC50 value of 0.19 μM.Formula:C22H22N2O2SColor and Shape:SolidMolecular weight:378.49Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formula:C18H18N4O5Color and Shape:SolidMolecular weight:370.36HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Formula:C24H24F2N2O2SColor and Shape:SolidMolecular weight:442.52HBV-IN-18
HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).Formula:C17H15F6N5O2Color and Shape:SolidMolecular weight:435.32SARS-CoV-2 3CLpro-IN-28
CAS:SARS-CoV-2 3CLpro-IN-28 (Compound 19) is an inhibitor of SARS-CoV-2 3CLpro, exhibiting an IC50 value of 0.018 μM.Formula:C27H18Cl2N4O4Color and Shape:SolidMolecular weight:533.362Polθ-IN-7
CAS:Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.Formula:C28H35F3N6O2Color and Shape:SolidMolecular weight:544.612Antibacterial agent 81
CAS:Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58Bilanafos
CAS:Bilanafos is an agent of Anti-Bacterial.Formula:C11H22N3O6PPurity:98%Color and Shape:SolidMolecular weight:323.28MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).Formula:C23H18Cl2FN5OColor and Shape:SolidMolecular weight:470.33Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formula:C23H24N6OColor and Shape:SolidMolecular weight:400.48PKZ18
CAS:PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.Formula:C22H26N2O3SPurity:98.08%Color and Shape:SolidMolecular weight:398.518BMIM-TFSI
CAS:BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.Formula:C10H15F6N3O4S2Color and Shape:SolidMolecular weight:419.364Mer-NF5003F
CAS:Mer-NF5003F (Stachybotrydial; F 1839M) is a sesquiterpene isolated from Stachybotrys, effective in inhibiting avian myeloblastosis virus (AMV) protease with an IC50 of 7.8 μM. It also inhibits sialyltransferases ST6N, ST3O, and ST3N with IC50 values of 0.61, 6.7, and 10 μg/mL, respectively, and fucosyltransferase with an IC50 of 11.3 μg/mL. Additionally, Mer-NF5003F exhibits in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multi-drug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).Formula:C23H30O5Molecular weight:386.48N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Formula:C11H9FN4OColor and Shape:SolidMolecular weight:232.213-Deazaguanosine
CAS:3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25Antibacterial agent 63
CAS:Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to aFormula:C35H43N9O14S2Color and Shape:SolidMolecular weight:877.9XR8-89
CAS:XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.Formula:C29H36N4O2SColor and Shape:SolidMolecular weight:504.69LasR-IN-1
LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.Formula:C23H21N3O2Color and Shape:SolidMolecular weight:371.43LpxA-IN-1
CAS:LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosaFormula:C21H11D7F3N5O3Color and Shape:SolidMolecular weight:452.44Valopicitabine
CAS:Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronicFormula:C15H24N4O6Purity:98%Color and Shape:SolidMolecular weight:356.37Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67Antileishmanial agent-6
Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.Formula:C24H26O8Color and Shape:SolidMolecular weight:442.46Laninamivir trifluoroacetate
CAS:Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.Formula:C15H23F3N4O9Purity:98%Color and Shape:SolidMolecular weight:460.363RAD51-IN-7
CAS:RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)Formula:C25H31N5O4S2Color and Shape:SolidMolecular weight:529.67Saroaspidin B
CAS:Saroaspidin B is a dimeric form of a biphenyl triphenol, characterized as an antibiotic compound.Formula:C25H32O8Color and Shape:SolidMolecular weight:460.52PLP_Snyder530
PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46And1 degrader 1
CAS:And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.Formula:C26H27Cl2N3OColor and Shape:SolidMolecular weight:468.42Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Formula:C29H52INO2Color and Shape:SolidMolecular weight:573.63Cap-dependent endonuclease-IN-17
CAS:CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.Formula:C24H20F2N3O7PSColor and Shape:SolidMolecular weight:563.47Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43FWM-1
FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.Formula:C15H11ClN4O4S2Color and Shape:SolidMolecular weight:410.86Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.Formula:C23H29N3O5Color and Shape:SolidMolecular weight:427.498-Hydroxyerythromycin A
CAS:8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.Formula:C37H67NO14Color and Shape:SolidMolecular weight:749.926Antibacterial agent 62
Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.Formula:C24H33BrN2O2Color and Shape:SolidMolecular weight:461.443'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite
CAS:3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.Formula:C41H50N9O3PColor and Shape:SolidMolecular weight:747.87GSK 932121
CAS:GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.Formula:C20H15ClF3NO4Purity:98%Color and Shape:SolidMolecular weight:425.79Arterolane
CAS:Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.Formula:C22H36N2O4Color and Shape:SolidMolecular weight:392.53Metallo-β-lactamase-IN-16
CAS:Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Formula:C16H16N8O4S3Color and Shape:SolidMolecular weight:480.54trans-RdRP-IN-5
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43MBX-1162
CAS:MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.Formula:C30H28N6Color and Shape:SolidMolecular weight:472.58Methyl piperazine-2-carboxylate
CAS:Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.Formula:C6H12N2O2Color and Shape:SolidMolecular weight:144.172BAS-118
CAS:BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.Formula:C20H18N2O2Color and Shape:SolidMolecular weight:318.369Antifungal agent 127
CAS:Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.Formula:C13H12ClN3OColor and Shape:SolidMolecular weight:261.707Antibacterial agent 266
CAS:Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.Formula:C13H11N3OColor and Shape:SolidMolecular weight:225.246SARS-CoV-IN-6
CAS:SARS-CoV-IN-6 (Compound 17) acts as an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, demonstrating an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. This compound reduces the cytopathic effects of single-round infectious particles (SRIP) infected with SARS-CoV-1 and SARS-CoV-2 replicons and inhibits the expression of SARS-CoVN proteins. The EC50 values for SRIP based on SARS-CoV-1 and SARS-CoV-2 replicons are 0.12 µM and 1.47 µM, respectively.Formula:C25H29N5O3Color and Shape:SolidMolecular weight:447.53(S)-Batylalcohol
CAS:(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.Formula:C21H44O3Color and Shape:SolidMolecular weight:344.572Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.Formula:C21H24ClN7Color and Shape:SolidMolecular weight:409.92AnCDA-IN-1
CAS:AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.Formula:C16H13ClN4O2Color and Shape:SolidMolecular weight:328.753ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Formula:C9H13N3Na3O12P3Color and Shape:SolidMolecular weight:517.1ACSS2-IN-1
CAS:ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.Formula:C27H25ClN6O2Color and Shape:SolidMolecular weight:500.98Anti-MRSA agent 23
CAS:Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.Formula:C20H17N5O3SColor and Shape:SolidMolecular weight:407.446β-Glucuronidase-IN-3
CAS:β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs).Formula:C10H7N3OSeColor and Shape:SolidMolecular weight:264.14Lapyrium chloride
CAS:Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formula:C21H35ClN2O3Molecular weight:398.979-tert-Butyldoxycycline
CAS:9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.Formula:C26H32N2O8Color and Shape:SolidMolecular weight:500.541SARS-CoV-2-IN-100
CAS:SARS-CoV-2-IN-100 (Compound 172) is a broad-spectrum antiviral agent against various SARS-CoV-2 variants. It works synergistically with Nirmatrelvir to reduce the risk of antiviral resistance.Formula:C29H23NO2Color and Shape:SolidMolecular weight:417.50iPAF1C
CAS:iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].
Formula:C27H26BrFN4OColor and Shape:SolidMolecular weight:521.42WRN inhibitor 11
CAS:WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.Formula:C34H35ClF3N9O5Color and Shape:SolidMolecular weight:742.15GC-78-HCl
CAS:GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.Formula:C25H25Cl3N4O4Molecular weight:551.85Cetefloxacin
CAS:Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.Formula:C20H16F3N3O3Molecular weight:403.35SARS 3CLpro-IN-1
CAS:SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.Formula:C22H38N4O2Color and Shape:SolidMolecular weight:390.56Cap-dependent endonuclease-IN-6
CAS:Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Formula:C23H21N3O3SColor and Shape:SolidMolecular weight:419.5Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Formula:C22H29FN3O10PColor and Shape:SolidMolecular weight:545.457ZIKV-IN-5
ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.Formula:C36H45NO4SiColor and Shape:SolidMolecular weight:583.83GSK-2878175
CAS:GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C27H23BClFN2O6SPurity:98%Color and Shape:SolidMolecular weight:568.81DC-159a
CAS:DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Formula:C21H23F2N3O40·5H2OColor and Shape:SolidMolecular weight:428.4295Antitrypanosomal agent 6
Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.Formula:C22H29Cl2N5OColor and Shape:SolidMolecular weight:450.4
