Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,957 products)
- Antibiotic(920 products)
- Antifection(23 products)
- DHFR(33 products)
- DNA/RNA Synthesis(708 products)
- HBV(176 products)
- HIV Protease(449 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
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Found 5842 products of "Microbiology/Virology"
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GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24GSK_WRN4
CAS:<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formula:C16H20N2O4SPurity:99.95%Color and Shape:SolidMolecular weight:336.41PKZ18
CAS:<p>PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.</p>Formula:C22H26N2O3SColor and Shape:SolidMolecular weight:398.518PLpro-IN-6
CAS:<p>PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.</p>Formula:C29H30N6OColor and Shape:SolidMolecular weight:478.59Valopicitabine dihydrochloride
CAS:<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C15H25ClN4O6Color and Shape:SolidMolecular weight:392.843HKT-IN-1
CAS:<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Formula:C12H11BrN2O3Color and Shape:SolidMolecular weight:311.131MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formula:C24H22Cl2N2O4SColor and Shape:SolidMolecular weight:505.41Tuberculosis inhibitor 4
<p>TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.</p>Formula:C23H26N2O3SColor and Shape:SolidMolecular weight:410.533-Deazaguanosine
CAS:<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.25Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formula:C17H20ClN3O2Purity:98%Color and Shape:SolidMolecular weight:333.81Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Formula:C35H43N9O14S2Color and Shape:SolidMolecular weight:877.9GC373
CAS:<p>GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.</p>Formula:C21H29N3O5Color and Shape:SolidMolecular weight:403.47ZK-806450
CAS:<p>ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.</p>Formula:C31H31N5OColor and Shape:SolidMolecular weight:489.611Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formula:C24H26O8Color and Shape:SolidMolecular weight:442.46Cyclophilin inhibitor 1
CAS:<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Formula:C30H42N2O6Color and Shape:SolidMolecular weight:526.66Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formula:C37H71N3O8SPurity:98%Color and Shape:SolidMolecular weight:718.04LN002
CAS:<p>LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.</p>Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40UNI418
CAS:<p>UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).</p>Formula:C22H16N6Color and Shape:SolidMolecular weight:364.40PLpro-IN-5
CAS:<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C26H33N3OColor and Shape:SolidMolecular weight:403.56Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formula:C17H10ClNO5Color and Shape:SolidMolecular weight:343.72Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formula:C16H11F2N3Color and Shape:SolidMolecular weight:283.28Neocryptolepine-Cl
CAS:<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formula:C16H11ClN2Color and Shape:SolidMolecular weight:266.725Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41trans-Clopenthixol
CAS:<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formula:C22H25ClN2OSColor and Shape:SolidMolecular weight:400.9652-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.632ATIC-IN-2
CAS:<p>ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.</p>Formula:C4H4N4O3SColor and Shape:SolidMolecular weight:188.165Piperacillin hydrate
CAS:<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Formula:C23H29N5O8SColor and Shape:SolidMolecular weight:535.57Anti-Trypanosoma cruzi agent-1
<p>Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.</p>Formula:C23H29N3O5Color and Shape:SolidMolecular weight:427.49MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Formula:C13H6Cl2N2O3Color and Shape:SolidMolecular weight:309.104Saphenamycin
CAS:<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formula:C23H18N2O5Purity:98%Color and Shape:SolidMolecular weight:402.40ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Formula:C31H35F3N4O3Color and Shape:SolidMolecular weight:568.63RSV-IN-5
CAS:<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formula:C28H37N7O2Color and Shape:SolidMolecular weight:503.64PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065LolCDE-IN-2
CAS:<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formula:C22H17N5OPurity:98%Color and Shape:SolidMolecular weight:367.40Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formula:C15H10F3N3OSColor and Shape:SolidMolecular weight:337.32A25822B
CAS:<p>A25822B is an antifungal agent.</p>Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66β-Glucuronidase-IN-2
<p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>Formula:C21H17Cl3O7Color and Shape:SolidMolecular weight:487.71Chitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Formula:C24H25N3O6Color and Shape:SolidMolecular weight:451.47Anti-infective agent 10
CAS:<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formula:C26H25N3O7SColor and Shape:SolidMolecular weight:523.56Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formula:C17H10ClF6N3O2SColor and Shape:SolidMolecular weight:469.79(Rac)-Plevitrexed
CAS:<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formula:C21H18ClN3O7SColor and Shape:SolidMolecular weight:491.902Telinavir
CAS:<p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>Formula:C33H44N6O5Color and Shape:SolidMolecular weight:604.74Antimalarial agent 2
<p>Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.</p>Formula:C27H25N3O5Color and Shape:SolidMolecular weight:471.5HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67Antibacterial agent 279
CAS:<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Formula:C9H11NO2SColor and Shape:SolidMolecular weight:197.25
