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Microbiology/Virology

Microbiology/Virology

Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.

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Found 5842 products of "Microbiology/Virology"

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  • HRSV/HMPV-IN-1

    CAS:
    <p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of &lt; 0.2 μM against human RSV-A and &lt; 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>
    Formula:C34H31ClF2N4O5S
    Color and Shape:Solid
    Molecular weight:681.15
  • KWR095

    CAS:
    <p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105
  • Rubropunctatin

    CAS:
    <p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>
    Formula:C21H23NO4
    Color and Shape:Solid
    Molecular weight:353.41
  • SLU-10906

    CAS:
    <p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>
    Formula:C22H21BFN5O2
    Color and Shape:Solid
    Molecular weight:417.244
  • NEU-1017

    CAS:
    <p>NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.</p>
    Formula:C33H31ClFN5O3S
    Color and Shape:Solid
    Molecular weight:632.147
  • PfCLK3-IN-1


    <p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>
    Formula:C28H27ClN4O4
    Color and Shape:Solid
    Molecular weight:518.99
  • Arterolane

    CAS:
    <p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>
    Formula:C22H36N2O4
    Color and Shape:Solid
    Molecular weight:392.53
  • Cap-dependent endonuclease-IN-7

    CAS:
    <p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>
    Formula:C36H28FN3O7S
    Color and Shape:Solid
    Molecular weight:665.69
  • (4-Aminobenzoyl)-D-glutamic acid

    CAS:
    <p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>
    Formula:C12H14N2O5
    Color and Shape:Solid
    Molecular weight:266.25
  • Antibacterial agent 62


    <p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>
    Formula:C24H33BrN2O2
    Color and Shape:Solid
    Molecular weight:461.44
  • HSV-TK substrate

    CAS:
    <p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>
    Formula:C11H15N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.27
  • Anti-MRSA agent 27

    CAS:
    <p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>
    Formula:C15H10F3N3OS
    Color and Shape:Solid
    Molecular weight:337.32
  • MED6-189

    CAS:
    <p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 &lt; 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>
    Formula:C17H26N2O
    Color and Shape:Solid
    Molecular weight:274.40
  • TCMDC-136230


    <p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>
    Formula:C24H34N4O2S
    Color and Shape:Solid
    Molecular weight:442.62
  • Pol I-IN-1


    <p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>
    Formula:C23H22N4O2
    Color and Shape:Solid
    Molecular weight:386.45
  • KPC-2-IN-2


    <p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>
    Formula:C12H10BN3O2S
    Color and Shape:Solid
    Molecular weight:271.1
  • ZINC4497834

    CAS:
    <p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>
    Formula:C18H19N5O3S
    Color and Shape:Solid
    Molecular weight:385.44
  • GS-9822

    CAS:
    <p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>
    Formula:C36H39ClN4O4S
    Color and Shape:Solid
    Molecular weight:659.24
  • SMCypI C31


    <p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>
    Formula:C27H30N4O2S
    Color and Shape:Solid
    Molecular weight:474.62
  • Narlaprevir

    CAS:
    <p>Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.</p>
    Formula:C36H61N5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:707.96
  • HIV-1 inhibitor-8


    <p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>
    Formula:C25H21N5OS
    Color and Shape:Solid
    Molecular weight:439.53
  • CB 30900

    CAS:
    <p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>
    Formula:C31H32FN5O9
    Color and Shape:Solid
    Molecular weight:637.61
  • PLpro-IN-7

    CAS:
    <p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>
    Formula:C30H34ClN7O
    Color and Shape:Solid
    Molecular weight:544.09
  • Antitubercular agent-11


    <p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>
    Formula:C16H15N3O4
    Color and Shape:Solid
    Molecular weight:313.31
  • NS2B/NS3-IN-2


    <p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>
    Formula:C24H21N3O5S
    Color and Shape:Solid
    Molecular weight:463.51
  • Triazophos

    CAS:
    <p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>
    Formula:C12H16N3O3PS
    Color and Shape:Solid
    Molecular weight:313.31
  • E6-272

    CAS:
    <p>E6-272, an inhibitor of HPV 16, induced early and late apoptosis in HPV16-positive cervical cancer cells and inhibited the proliferation of SiHa and CaSki.</p>
    Formula:C26H28N2O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:384.51
  • FWM-1


    <p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>
    Formula:C15H11ClN4O4S2
    Color and Shape:Solid
    Molecular weight:410.86
  • OPC-167832

    CAS:
    <p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>
    Formula:C21H20ClF3N2O4
    Color and Shape:Solid
    Molecular weight:456.84
  • Purine phosphoribosyltransferase-IN-2


    <p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>
    Formula:C11H15N5Na4O10P2
    Color and Shape:Solid
    Molecular weight:531.17
  • β-Glucuronidase-IN-2


    <p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>
    Formula:C21H17Cl3O7
    Color and Shape:Solid
    Molecular weight:487.71
  • 844-TFM


    <p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>
    Formula:C24H25F3N4O2
    Color and Shape:Solid
    Molecular weight:458.48
  • 2'-(2-Nitrobenzyl)-ATP

    CAS:
    <p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>
    Formula:C17H21N6O15P3
    Color and Shape:Solid
    Molecular weight:642.30
  • CDA-IN-4

    CAS:
    <p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>
    Formula:C10H9BrN4O2S
    Color and Shape:Solid
    Molecular weight:329.17
  • OUN58101

    CAS:
    <p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>
    Formula:C32H36N6O6
    Color and Shape:Solid
    Molecular weight:600.66
  • Ladirubicin

    CAS:
    <p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>
    Formula:C29H31NO11S
    Color and Shape:Solid
    Molecular weight:601.62
  • Saphenamycin

    CAS:
    <p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>
    Formula:C23H18N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.40
  • TAN-1057C

    CAS:
    <p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>
    Formula:C13H25N9O3
    Color and Shape:Solid
    Molecular weight:355.4
  • FPI-1465

    CAS:
    <p>FPI-1465: Dual serine-β-lactamase &amp; PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>
    Formula:C11H18N4O7S
    Color and Shape:Solid
    Molecular weight:350.35
  • Antibacterial agent 262

    CAS:
    <p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>
    Formula:C17H18F2N6O4S3
    Color and Shape:Solid
    Molecular weight:504.554
  • Erythromycin B

    CAS:
    <p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>
    Formula:C37H67NO12
    Color and Shape:Solid
    Molecular weight:717.93
  • XR8-69


    <p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>
    Formula:C26H30N4O2S
    Color and Shape:Solid
    Molecular weight:462.61
  • HCV-IN-7

    CAS:
    <p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>
    Formula:C40H48N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.92
  • 12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47
  • 5-Iminodaunorubicin hydrochloride

    CAS:
    <p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>
    Formula:C27H31ClN2O9
    Color and Shape:Solid
    Molecular weight:563.00
  • Diclosulam

    CAS:
    <p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>
    Formula:C13H10Cl2FN5O3S
    Color and Shape:Solid
    Molecular weight:406.22
  • T-2513 hydrochloride

    CAS:
    <p>T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.</p>
    Formula:C25H28ClN3O5
    Color and Shape:Solid
    Molecular weight:485.96
  • DC-159a

    CAS:
    <p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>
    Formula:C21H23F2N3O40·5H2O
    Color and Shape:Solid
    Molecular weight:428.4295
  • Anticaries agent-1

    CAS:
    <p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>
    Formula:C15H12O4
    Color and Shape:Solid
    Molecular weight:256.253
  • Antifungal agent 19


    <p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>
    Formula:C19H18F4O2
    Color and Shape:Solid
    Molecular weight:354.34