
Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,957 products)
- Antibiotic(920 products)
- Antifection(23 products)
- DHFR(33 products)
- DNA/RNA Synthesis(708 products)
- HBV(176 products)
- HIV Protease(449 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
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Found 5842 products of "Microbiology/Virology"
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NITD-688
CAS:<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Formula:C25H32N4O3S2Color and Shape:SolidMolecular weight:500.68Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formula:C18H16Br2O2Color and Shape:SolidMolecular weight:424.13LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Formula:C30H31N5O3Color and Shape:SolidMolecular weight:509.6GHP-88309
CAS:<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formula:C16H11FN2OColor and Shape:SolidMolecular weight:266.27Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Color and Shape:SolidMolecular weight:468.453VPC-80051
CAS:<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formula:C16H13F2N3OColor and Shape:SolidMolecular weight:301.291KKL-40
CAS:<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Formula:C16H9F4N3O2Color and Shape:SolidMolecular weight:351.255Jun13296
CAS:<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Formula:C30H34N6OColor and Shape:SolidMolecular weight:494.631Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formula:C23H21N3O4SColor and Shape:SolidMolecular weight:435.5Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Color and Shape:SolidMolecular weight:322.093Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formula:C21H27N3SColor and Shape:SolidMolecular weight:353.52NRTT-IN-1
CAS:<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formula:C28H24FN5O5Color and Shape:SolidMolecular weight:529.519MIV-150
CAS:<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36Xanthosine-5'-Triphosphate trisodium
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Formula:C10H12N4Na3O15P3Color and Shape:SolidMolecular weight:590.111Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formula:C12H10N4SColor and Shape:SolidMolecular weight:242.3BAY-364
CAS:<p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>Formula:C23H19N3O4Color and Shape:SolidMolecular weight:401.41Altersolanol A
CAS:<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Formula:C16H16O8Color and Shape:SolidMolecular weight:336.29Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formula:C7H14N3NaO8SColor and Shape:SolidMolecular weight:323.26GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71Teslexivir
CAS:<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formula:C35H36BrN3O4Purity:98%Color and Shape:SolidMolecular weight:642.58EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Formula:C25H40ClN3O2Color and Shape:SolidMolecular weight:450.06BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Formula:C18H17NO3SColor and Shape:SolidMolecular weight:327.397Cefclidin
CAS:<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formula:C21H26N8O6S2Color and Shape:SolidMolecular weight:550.611Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formula:C20H12ClN3O5Color and Shape:SolidMolecular weight:409.78Cap-dependent endonuclease-IN-5
CAS:<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Formula:C27H21F2N3O4S2Color and Shape:SolidMolecular weight:553.602-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.632Piperacillin hydrate
CAS:<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Formula:C23H29N5O8SColor and Shape:SolidMolecular weight:535.57HKI12134085
CAS:<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Formula:C18H18F3N3O5SColor and Shape:SolidMolecular weight:445.41MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Formula:C15H10BrN5O2SColor and Shape:SolidMolecular weight:404.24MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Formula:C13H6Cl2N2O3Color and Shape:SolidMolecular weight:309.104ALG-000184
CAS:<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formula:C23H20FN4Na2O8PColor and Shape:SolidMolecular weight:576.379AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formula:C26H43FO7SColor and Shape:SolidMolecular weight:518.68EBOV-IN-10
CAS:<p>EBOV-IN-10 is an orally active inhibitor of the Ebola virus (EBOV) with an EC50 value of 0.19 μM.</p>Formula:C22H22N2O2SColor and Shape:SolidMolecular weight:378.49L-697639
CAS:<p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>Formula:C18H21N3O2Color and Shape:SolidMolecular weight:311.38Epolactaene
CAS:<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formula:C21H27NO6Color and Shape:SolidMolecular weight:389.44Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:<p>Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).</p>Formula:C33H41NO6SColor and Shape:SolidMolecular weight:579.75cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formula:C23H21ClFN3O5Color and Shape:SolidMolecular weight:473.88BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61Cephalosporin C
CAS:<p>Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.</p>Formula:C16H21N3O8SColor and Shape:SolidMolecular weight:415.418Aurantiogliocladin
CAS:<p>Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.</p>Formula:C10H12O4Color and Shape:SolidMolecular weight:196.2MBL-IN-5
CAS:<p>MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.</p>Formula:C20H16ClNO3Color and Shape:SolidMolecular weight:353.80HBV-IN-31
CAS:<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formula:C23H18ClNO6Color and Shape:SolidMolecular weight:439.85VV261
CAS:<p>VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.</p>Formula:C28H34FN3O11Color and Shape:SolidMolecular weight:607.58SARS-CoV-2-IN-82
CAS:<p>SARS-CoV-2-IN-82 (compound A) acts as an inhibitor of the Programmed-1 ribosomal frameshift (-1 PRF) in SARS-CoV-2 [1].</p>Formula:C18H18N2Color and Shape:SolidMolecular weight:262.35RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formula:C22H26BrN5O4SColor and Shape:SolidMolecular weight:536.44QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Formula:C15H14BFO8Purity:98%Color and Shape:SolidMolecular weight:352.085-Fluorouridine 5'-phosphate
CAS:<p>5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.</p>Formula:C9H12FN2O9PColor and Shape:SolidMolecular weight:342.172(E)-Antiviral agent 67
CAS:<p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.374Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Formula:C22H20Cl2N4Se2Color and Shape:SolidMolecular weight:569.25

