Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(3,348 products)
- Antibiotic(936 products)
- Antifection(26 products)
- DHFR(32 products)
- DNA/RNA Synthesis(798 products)
- HBV(189 products)
- HIV Protease(505 products)
- HSV(97 products)
- Integrase(2 products)
- Ribosome(11 products)
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Found 6384 products of "Microbiology/Virology"
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CYP51-IN-7
CAS:CYP51-IN-7 (compound 1g) is an analogue of Fluconazole and serves as an effective antifungal agent. It exhibits inhibitory activity against Microsporum gypseum and Candida albicans, with MIC80 values of 62.5 ng/mL and 250 ng/mL, respectively.Formula:C21H21ClF2N4OMolecular weight:418.87Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45Enzyme-IN-3 disodium
CAS:Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Formula:C20H13N3Na2O8S2Color and Shape:SolidMolecular weight:533.442HBV-IN-19 TFA
CAS:HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.Formula:C26H31F3N2O8Color and Shape:SolidMolecular weight:556.53Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formula:C9H20N2O8Color and Shape:SolidMolecular weight:284.26Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26CDA-IN-1
CAS:CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Formula:C15H14N2O6Color and Shape:SolidMolecular weight:318.281Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formula:C23H27N3O2SColor and Shape:SolidMolecular weight:409.54RAD51-IN-7
CAS:RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)Formula:C25H31N5O4S2Color and Shape:SolidMolecular weight:529.67(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS:(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.Formula:C26H36F3NO4SColor and Shape:SolidMolecular weight:515.629Ambelline
CAS:Ambelline has antitumor activity.Formula:C18H21NO5Purity:98%Color and Shape:SolidMolecular weight:331.36Doxazosin impurity 12
CAS:Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.
Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217EFdA-TP tetrasodium
CAS:EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.Formula:C12H11FN5Na4O12P3Purity:98%Color and Shape:SolidMolecular weight:621.12Kalafungin
CAS:Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Formula:C16H12O6Color and Shape:SolidMolecular weight:300.26Piperacillin hydrate
CAS:Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Formula:C23H29N5O8SColor and Shape:SolidMolecular weight:535.57Benzohydroxamic acid
CAS:Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Formula:C7H7NO2Color and Shape:SolidMolecular weight:137.136Anti-ToCV agent 1
Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.Formula:C22H19FN2O5SColor and Shape:SolidMolecular weight:442.46BDM91288
CAS:BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].Formula:C17H22ClN5Color and Shape:SolidMolecular weight:331.84MA220607
CAS:MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].Formula:C34H38INColor and Shape:SolidMolecular weight:587.58Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formula:C17H23F3N8O10SColor and Shape:SolidMolecular weight:588.47PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formula:C22H29N5O2Color and Shape:SolidMolecular weight:395.5Uridine 3',5'-diphosphate
CAS:Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].Formula:C9H14N2O12P2Color and Shape:SolidMolecular weight:404.16Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07H2S scavenger 1 (triflate)
H2S scavenger 1 triflate (Compound 7b) serves as a selective H2S depleting agent, particularly against glutathione. This compound impedes the formation of bacterial biofilms and enhances the sensitivity of Staphylococcus aureus to gentamicin or photosensitizers by depleting H2S.Formula:C13H16F3N5O6SMolecular weight:427.36Cap-dependent endonuclease-IN-5
CAS:Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Formula:C27H21F2N3O4S2Color and Shape:SolidMolecular weight:553.60A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98Metallo-β-lactamase-IN-14
CAS:Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].Formula:C20H22N8O2S2Color and Shape:SolidMolecular weight:470.57L-2'-Fd4C
CAS:L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Formula:C9H10FN3O3Color and Shape:SolidMolecular weight:227.19SAG-524
CAS:SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].Formula:C30H32ClN5O4SColor and Shape:SolidMolecular weight:594.12NNRT-IN-2
CAS:NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formula:C19H14F3N5O3Molecular weight:417.34Pks13-TE inhibitor 4
CAS:Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.Formula:C26H25N5O6Molecular weight:503.51Antifungal agent 39
CAS:Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.Formula:C23H22ClN3O5Color and Shape:SolidMolecular weight:455.89Antibacterial agent 204
CAS:Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].Formula:C14H18N2Color and Shape:SolidMolecular weight:214.31Antibacterial agent 99
CAS:Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Formula:C27H27BrN2Color and Shape:SolidMolecular weight:459.42Antibiofilm agent-14
CAS:Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.Formula:C26H30ClN3OColor and Shape:SolidMolecular weight:435.989SARS-CoV-2-IN-80
CAS:SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].Formula:C16H10O2SColor and Shape:SolidMolecular weight:266.31DHX9-IN-9
CAS:DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].Formula:C21H21ClFN5O3S2Color and Shape:SolidMolecular weight:510Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Formula:C29H52INO2Color and Shape:SolidMolecular weight:573.63RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Color and Shape:SolidMolecular weight:763.11Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46DHFS-IN-1
CAS:DHFS-IN-1 (Compound 3) is an inhibitor of dihydrofolate synthetase (DHFS) with an IC50 of 2.6 μM. It is applicable for research into infectious diseases related to bacterial folate synthesis.Formula:C16H16N8O2Color and Shape:SolidMolecular weight:352.35HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColor and Shape:SolidMolecular weight:443.43Cilastatin ammonium salt
CAS:Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formula:C16H29N3O5SColor and Shape:SolidMolecular weight:375.48Cefamandole lithium
CAS:Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formula:C18H17LiN6O5S2Color and Shape:SolidMolecular weight:468.44SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formula:C30H37Cl2N5O3Color and Shape:SolidMolecular weight:586.552,5-Di-tert-butyl-1,4-benzoquinone
CAS:2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.Formula:C14H20O2Color and Shape:SolidMolecular weight:220.31MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Color and Shape:SolidMolecular weight:373.18Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17Streptothricin F
CAS:Streptothricin F is a biochemical.Formula:C19H34N8O8Color and Shape:SolidMolecular weight:502.52MK-8876
CAS:MK-8876 is an Inhibitor of HCV NS5B Site D.Formula:C32H24F2N4O5SPurity:98%Color and Shape:SolidMolecular weight:614.62
