Microbiology/Virology

Gloxazone is an effective anaplasmacide with toxicity.

Avibactam free acid is a potent β-lactamase inhibitor exhibiting covalent and reversible properties, capable of inhibiting TEM-1, P99, and CTX-M-15.

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.

Sulfamerazine D4 is deuterium-labeled, a sulfonamide that blocks bacterial folic acid production by binding instead of PABA.

2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.

Piperanine is a useful organic compound for research related to life sciences. The catalog number is T125252 and the CAS number is 23512-46-1.

BPN-15477 is a splicing modulator compound (SMC) that which restores correct splicing of exon 20 in ELP1 (Elongator complex protein 1).

EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory, and antioxidant activities for the study of neurological disorders.

Bixafen is a succinate dehydrogenase inhibitor with hepatotoxicity, pancreotoxicity, and fungicidal activity, used for controlling crop diseases.

Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).

Balapiravir (R1626) is a prodrug targeting HCV polymerase, discontinued due to safety concerns like lymphopenia and other serious side effects.

Lactoferrin (17-41) (Standard) is a reference material for analytical use. Lactoferrin (17-41) exhibits broad-spectrum antimicrobial activity.

Ibrexafungerp (MK 3118) is a β-1,3-glucan synthase inhibitor with antifungal activity.

Ensitrelvir (S-217622) fumarate, an oral SARS-CoV-2 3CL protease inhibitor with an IC50 of 13 nM, is non-covalent and non-peptidic.

Ticlatone (landromil) is a synthetic antifungal used to research pathogenic fungal infections.

Antibacterial agent 18 is a multi-armed AIE molecule with antibacterial activity, inhibiting the growth of both Gram-positive and Gram-negative bacteria.

PK 11195 binds translocator protein; anti-Leishmania with IC50s: L. amazonensis 14.2 μM, L. major 8.2 μM, L. braziliensis 3.5 μM.

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

Etzadroxil, a volatile ester, treats drug-resistant urinary infections.

RNase L-IN-1 is an RNase L inhibitor with potential anticancer activity and inhibits viral replication.

Diethylcarbamazine citrate treats filariasis, targeting Loa loa and Wucheria bancrofti.

D-Cystine, the D-enantiomer of L-Cystine, functions as an inhibitor of L-aspartate-β-semialdehyde dehydrogenase (ASADH) derived from Escherichia coli.

Lactate potassium inhibits bacterial growth and serves as a pH regulator and preservative.

Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.

G-418, or Geneticin, is an aminoglycoside antibiotic similar to gentamicin; it's toxic to all cells and blocks protein synthesis.

Albendazole sulfoxide D3 is deuterium-labeled Albendazole sulfoxide. Albendazole sulfoxide is a broad-spectrum anthelmintic.

2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.

G907 is an antagonist of the ATP-binding cassette (ABC) transporter protein MsbA with bactericidal activity. G907 inhibits MsbA in E. coli.

Prochloraz manganese (Standard) is the standard substance of Prochloraz manganese, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Prochloraz manganese, an antifungal agent utilized in the agricultural sectors , serves to protect crops by inhibiting fungal growth.

Cefodizime: a new, well-tolerated cephalosporin antibiotic with immunomodulatory properties for serious respiratory and urinary infections.

Anti-SARS-CoV-2 Spike Antibody (9G419) is a Rabbit IgG monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Branaplam hydrochloride (LMI070; NVS-SM1) is an orally active SMN2 splicing modulator (EC50 20 nM) that also inhibits hERG channels (IC50 6.3 μM).

Tilbroquinol is an antiprotozoal agent effective against amoebiasis.

Sulfapyridine (Standard) is the standard substance of Sulfapyridine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

(-)-JNJ-A07 is a selective and potent dengue virus (DENV) inhibitor (EC50:31 nM) with antiviral activity for the study of dengue virus infections.

4-Aminosalicylic acid (Standard) is the standard substance of 4-Aminosalicylic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Antifungal agent 1 is an effective antifungal agent.

3'-F-3'-dA(Bz)-2'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside.

Diethylamine NONOate diethylammonium salt (DEA NONOate diethylamine) is a nitric oxide donor with antibacterial activity and inhibits the growth of E. coli.

Torcitabine is useful against the hepatitis B virus.

5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite is a Nucleoside Phosphoramidite.

Kanamycin sulfate (Standard) is the standard substance of Kanamycin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.

Vamidothion is a polar organophosphorus insecticide and acaricide

Ofurace (Standard) is the standard substance of Ofurace, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ofurace is a fungicide.

2-Nitrobenzaldehyde Semicarbazone, a Semicarbazide derivative, detects antibiotic Nitrofurazone use.

DMT-dC(ac) Phosphoramidite is a phosphoramidite monomer that has been modified for use in oligonucleotide synthesis.

Nosiheptide (Standard) is the standard substance of Nosiheptide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nosiheptide (Multhiomycin), a thiopeptide antibiotic synthesized by Streptomyces actuosus, serves as a potent feed additive to promote animal growth. It functions by hindering bacterial protein synthesis and is distinguished by an indole side ring system and regiospecific hydroxyl groups on its macrocyclic core.

Praziquantel (Standard) is the standard substance of Praziquantel, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite is a Nucleoside Phosphoramidite.