Microbiology/Virology

α-Cembrenediol is a useful organic compound for research related to life sciences and the catalog number is T124625.

Manumycin B is an antibiotic with antitumor properties. It acts as an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 15 mM.

JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with pEC50 and pCC50 values of 7.86 and 4.29, respectively, in Hela cells. It inhibits the initiation or early elongation phases, thereby preventing RSV replication and transcription.

Quorum sensing involves bacteria using AHLs to coordinate gene expression for biofilm formation and virulence, via LuxR regulators.

Laccase-IN-5 (Compound 2b) is an inhibitor of laccase with an IC50 of 0.82 μM. It enhances cell membrane permeability, restricts mycelial growth, disrupts cell walls, and induces oxidative stress responses. Laccase-IN-5 exhibits antifungal activity against various plant pathogenic fungi and oomycetes, effectively inhibiting B. dothidea with an EC50 of 0.96 mg/L.

Pomolic Acid 3-Acetate, an antitubercular compound, exhibits a minimum inhibitory concentration (MIC) of 32 μM against Mycobacterium tuberculosis H37Rv [1].

<p>CpCDPK1/TgCDPK1-IN-3 inhibits Cp/TgCDPK1; IC50: 0.003/0.0036 µM. It's used to research Toxoplasma, Cryptosporidium diseases.</p>

<p>Desethylene ciprofloxacin is ciprofloxacin's major metabolite and degradation product, also formed by chlorination and oxygenation in wastewater treatment.</p>

Urechistachykinin II (Uru-TK II) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms.

<p>Cyclic L27-11 is a cyclic peptide analog antibiotic that exhibits potent antimicrobial activity against specific bacteria, particularly Pseudomonas sp. It is highly effective against Pseudomonas aeruginosa, demonstrating nanomolar-level antibacterial activity. The mechanism of action for Cyclic L27-11 involves interfering with the function of the bacterial outer membrane protein LptD, inhibiting the normal transport of lipopolysaccharide (LPS). This inhibition leads to the accumulation of membrane-like substances within the bacterial cell, adversely affecting bacterial survival. Consequently, Cyclic L27-11 is a promising candidate for antimicrobial agent development.</p>

<p>Lytixar (LTX-109): Synthetic peptide effective against various resistant S. aureus strains, MIC 2-4 μg/ml, fast-acting regardless of prior resistance.</p>

Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].

<p>Ro 09-1428, a parenteral cephalosporin, has high antipseudomonal activity.</p>

TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).

XMP-629, an endotoxin inhibitor, is used potentially for the treatment of impetigo and acne rosacea.

Peniterphenyl A from deep-sea Penicillium blocks HSV-1/2 entry by targeting glycoprotein D, hindering adsorption and fusion.

Lactoferricin B (4-14), bovine (TFA), a 4-14 residue peptide from lactoferrin, has broad-spectrum antimicrobial properties.

Meralein has topical anti-infective activity.

3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.

<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>