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Beta Amyloid

Beta Amyloid

Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.

Found 204 products of "Beta Amyloid"

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  • Semagacestat
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    Semagacestat

    CAS:
    <p>Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).</p>
    Formula:C19H27N3O4
    Purity:97.1% - 99.9%
    Color and Shape:Solid
    Molecular weight:361.44

    Ref: TM-T6125

  • Aftin-4
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    Aftin-4

    CAS:
    <p>Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.</p>
    Formula:C20H28N6O
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:368.48

    Ref: TM-T4364

  • LX2343
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    LX2343

    CAS:
    <p>LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.</p>
    Formula:C22H19ClN2O6S
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:474.91

    Ref: TM-T4398

  • LY2811376
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    LY2811376

    CAS:
    <p>LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).</p>
    Formula:C15H14F2N4S
    Purity:99% - 99.01%
    Color and Shape:Solid
    Molecular weight:320.36

    Ref: TM-T2639

  • Anle138b
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    Anle138b

    CAS:
    <p>Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease</p>
    Formula:C16H11BrN2O2
    Purity:98.88% - 99.82%
    Color and Shape:Solid
    Molecular weight:343.17

    Ref: TM-T5447

  • MK-0752
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    MK-0752

    CAS:
    <p>MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).</p>
    Formula:C21H21ClF2O4S
    Purity:98% - 99.55%
    Color and Shape:Solid
    Molecular weight:442.9

    Ref: TM-T2625

  • PiB
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    PiB

    CAS:
    <p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>
    Formula:C14H12N2OS
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:256.32

    Ref: TM-T21000

  • Frentizole
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    Frentizole

    CAS:
    <p>Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction</p>
    Formula:C15H13N3O2S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:299.35

    Ref: TM-T7527

  • RO4929097
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    RO4929097

    CAS:
    <p>RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).</p>
    Formula:C22H20F5N3O3
    Purity:98.5% - 99.51%
    Color and Shape:Solid
    Molecular weight:469.4

    Ref: TM-T6274

  • ARN2966
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    ARN2966

    CAS:
    <p>ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.</p>
    Formula:C12H12N2O
    Purity:99.52% - 99.86%
    Color and Shape:Solid
    Molecular weight:200.24

    Ref: TM-T7490

  • CRANAD 2
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    CRANAD 2

    CAS:
    <p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>
    Formula:C23H25BF2N2O2
    Purity:99.44%
    Color and Shape:Dark Blue To Black Powder
    Molecular weight:410.27

    Ref: TM-T22694

  • 1,1'-Methylenedi-2-naphthol
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    1,1'-Methylenedi-2-naphthol

    CAS:
    <p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>
    Formula:C21H16O2
    Purity:98.91%
    Color and Shape:Light Pink To Light Brown Crystalline Powder
    Molecular weight:300.35

    Ref: TM-T9335

  • TAE-1
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    TAE-1

    CAS:
    <p>TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.</p>
    Formula:C39H51I3N6O9
    Purity:94.58%
    Color and Shape:Solid
    Molecular weight:1128.57

    Ref: TM-T21825

  • Pyridoxal 5'-phosphate hydrate
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    Pyridoxal 5'-phosphate hydrate

    CAS:
    <p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>
    Formula:C8H10NO6P
    Purity:97.52%
    Color and Shape:Solid
    Molecular weight:247.14

    Ref: TM-T5085

  • PBD-150
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    PBD-150

    CAS:
    <p>PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)</p>
    Formula:C15H20N4O2S
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:320.41

    Ref: TM-T7905

  • Miridesap
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    Miridesap

    CAS:
    <p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>
    Formula:C16H24N2O6
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:340.37

    Ref: TM-T7295

  • Azeliragon HCl
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    Azeliragon HCl

    CAS:
    <p>Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.</p>
    Formula:C32H40Cl3N3O2
    Color and Shape:Solid
    Molecular weight:605.04

    Ref: TM-T2507L2

  • EUK-134
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    EUK-134

    CAS:
    <p>EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.</p>
    Formula:C18H18ClMnN2O4
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:416.74

    Ref: TM-T6495

  • JLK6
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    JLK6

    CAS:
    <p>JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling</p>
    Formula:C10H8ClNO3
    Purity:96.50%
    Color and Shape:Solid
    Molecular weight:225.63

    Ref: TM-T21890

  • Cromoglicic acid
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    Cromoglicic acid

    CAS:
    <p>Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.</p>
    Formula:C23H16O11
    Purity:99.55% - >99.99%
    Color and Shape:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)
    Molecular weight:468.37

    Ref: TM-T8239