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Beta Amyloid

Beta Amyloid

Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.

Found 204 products of "Beta Amyloid"

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  • PE859

    CAS:
    <p>PE859 is a potent inhibitor of both tau and Aβ aggregation.</p>
    Formula:C28H24N4O2
    Purity:98.8% - 99.09%
    Color and Shape:Solid
    Molecular weight:448.52
  • Solanezumab

    CAS:
    <p>Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.</p>
    Purity:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:144.1 (kDa)
  • γ-Secretase modulator 13

    CAS:
    <p>γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.</p>
    Formula:C22H23FN6S
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:422.52
  • Remternetug

    CAS:
    <p>Remternetug is a humanized IgG1-kappa monoclonal antibody that targets the N3pGlu peptide of the amyloid beta A4 precursor protein (APP) Aβ42.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Dezamizumab

    CAS:
    <p>Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Bapineuzumab

    CAS:
    <p>Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).</p>
    Purity:95%
    Color and Shape:Liquid
  • Homotaurine-d6

    CAS:
    <p>Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.</p>
    Formula:C3D6H3NO3S
    Color and Shape:Solid
    Molecular weight:145.21
  • 4-(6-Bromo-2-benzothiazolyl)benzenamine

    CAS:
    <p>4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.</p>
    Formula:C13H9BrN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:305.19
  • Nicardipine pyridine metabolite II

    CAS:
    <p>Nicardipine pyridine metabolite II is a biaoctive chemical.</p>
    Formula:C26H27N3O6
    Color and Shape:Solid
    Molecular weight:477.51
  • 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine

    CAS:
    <p>4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).</p>
    Formula:C14H11BrN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.22
  • Aftin-5

    CAS:
    <p>Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.</p>
    Formula:C19H26N6O
    Color and Shape:Solid
    Molecular weight:354.45
  • AZ4800

    CAS:
    <p>AZD4800 is a gamma secretase modulators.</p>
    Formula:C24H29N5O3
    Color and Shape:Solid
    Molecular weight:435.52
  • THK-523

    CAS:
    <p>THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.</p>
    Formula:C17H15FN2O
    Color and Shape:Solid
    Molecular weight:282.31
  • BChE-IN-8

    CAS:
    <p>BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.</p>
    Formula:C18H12BrN7O2
    Color and Shape:Solid
    Molecular weight:438.24
  • JNJ-40418677

    CAS:
    <p>JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.</p>
    Formula:C26H22F6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.44
  • Glutaminyl Cyclase Inhibitor 2

    CAS:
    <p>Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).</p>
    Formula:C19H20FN3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:309.38
  • Chrysamine G

    CAS:
    <p>Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.</p>
    Formula:C26H16N4Na2O6
    Color and Shape:Solid
    Molecular weight:526.416
  • K 01-162

    CAS:
    <p>K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.</p>
    Formula:C15H14BrN
    Color and Shape:Solid
    Molecular weight:288.18
  • YIAD-0205

    CAS:
    <p>YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familial</p>
    Formula:C26H16Br2ClN3
    Color and Shape:Solid
    Molecular weight:565.69
  • OAB-14

    CAS:
    <p>OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.</p>
    Formula:C32H46N4O2
    Color and Shape:Solid
    Molecular weight:518.73