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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

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  • Bromfenac

    CAS:
    <p>Bromfenac, a potent COX inhibitor, targets ocular inflammation with IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2.</p>
    Formula:C15H12BrNO3
    Color and Shape:Solid
    Molecular weight:334.16
  • Zaltoprofen

    CAS:
    <p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>
    Formula:C17H14O3S
    Purity:99.72%
    Color and Shape:Off-White To Pale Yellow Crystalline Solid
    Molecular weight:298.36
  • α-Humulene

    CAS:
    <p>α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory</p>
    Formula:C15H24
    Purity:97.18% - 97.18%
    Color and Shape:Liquid
    Molecular weight:204.35
  • Ginsenoside Rd

    CAS:
    <p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.13% - 99.92%
    Color and Shape:Solid
    Molecular weight:947.15
  • (±)-Catechin

    CAS:
    <p>(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.</p>
    Formula:C15H14O6
    Purity:98.46%
    Color and Shape:White To Yellow Powder
    Molecular weight:290.27
  • Mavacoxib

    CAS:
    <p>Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.</p>
    Formula:C16H11F4N3O2S
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:385.34
  • Choline Fenofibrate

    CAS:
    <p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>
    Formula:C22H28ClNO5
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:421.91
  • Tolmetin sodium dihydrate

    CAS:
    <p>Tolmetin sodium dihydrate is an oral NSAID inhibiting COX-1 and COX-2, widely used in studies of prostaglandin synthesis and anti-inflammatory mechanisms.</p>
    Formula:C15H18NNaO5
    Purity:99.57%
    Color and Shape:Crystalline Solid
    Molecular weight:315.3
  • Bromfenac Sodium

    CAS:
    <p>Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID) and an orally available COX inhibitor, which has anti-inflammatory activity.</p>
    Formula:C15H11BrNO3·Na
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:356.15
  • Regaloside B

    CAS:
    <p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>
    Formula:C20H26O11
    Purity:99.4% - 99.57%
    Color and Shape:Solid
    Molecular weight:442.41
  • α-Demethylnaproxen

    CAS:
    <p>α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)</p>
    Formula:C13H12O3
    Purity:97.57%
    Color and Shape:Off-White Solid
    Molecular weight:216.23
  • FR 122047

    CAS:
    <p>FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM</p>
    Formula:C23H26ClN3O3S
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:459.99
  • Jaceosidin

    CAS:
    <p>Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.</p>
    Formula:C17H14O7
    Purity:98.23% - 99.28%
    Color and Shape:Solid
    Molecular weight:330.29
  • Dexketoprofen trometamol

    CAS:
    <p>Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations.</p>
    Formula:C20H25NO6
    Purity:99.97% - 99.98%
    Color and Shape:Solid
    Molecular weight:375.42
  • Hamaudol

    CAS:
    <p>Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).</p>
    Formula:C15H16O5
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:276.28
  • Indomethacin heptyl ester

    CAS:
    <p>Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2</p>
    Formula:C26H30ClNO4
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:455.97
  • Harpagoside

    CAS:
    <p>Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.</p>
    Formula:C24H30O11
    Purity:99.71% - ≥95%
    Color and Shape:White To Off-White Powder
    Molecular weight:494.49
  • Suprofen

    CAS:
    <p>Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic.</p>
    Formula:C14H12O3S
    Purity:99.23% - 99.33%
    Color and Shape:Solid
    Molecular weight:260.31
  • Chlorthenoxazine

    CAS:
    <p>Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.</p>
    Formula:C10H10ClNO2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:211.64
  • 20(S)-Ginsenoside Rg3

    CAS:
    <p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>
    Formula:C42H72O13
    Purity:98.11% - 99.93%
    Color and Shape:Solid
    Molecular weight:785.01