
Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 561 products of "Cyclooxygenase (COX) Inhibitors"
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LY 25648
CAS:<p>LY 25648 is an antagonist of leukotriene B4.</p>Formula:C19H27NO2SColor and Shape:SolidMolecular weight:333.49ZXX2-77
CAS:<p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>Formula:C13H13ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:296.77LY 150310
CAS:<p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26PC407-ws
CAS:<p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>Formula:C24H18F3N3Na2O5SPurity:98%Color and Shape:SolidMolecular weight:563.46Isonixin
CAS:<p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>Formula:C14H14N2O2Purity:98%Color and Shape:SolidMolecular weight:242.27Tenosal
CAS:<p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>Formula:C12H8O4SPurity:98%Color and Shape:SolidMolecular weight:248.25LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Formula:C18H25NO2SPurity:98%Color and Shape:SolidMolecular weight:319.46L 748780
CAS:<p>L 748780 is a selective inducible COX-2 inhibitor.</p>Formula:C19H14Cl3NO4Purity:98%Color and Shape:SolidMolecular weight:426.68Eicosatetraynoic acid
CAS:<p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>Formula:C20H24O2Purity:98%Color and Shape:SolidMolecular weight:296.4Feprazone
CAS:<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Formula:C20H20N2O2Purity:99.6% - 99.89%Color and Shape:SolidMolecular weight:320.39Enflicoxib
CAS:<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Formula:C16H12F5N3O2SPurity:99.88%Color and Shape:SolidMolecular weight:405.34Carpro-AM1
CAS:<p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>Formula:C21H18ClN3OColor and Shape:SolidMolecular weight:363.84Tilmacoxib
CAS:<p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>Formula:C16H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:338.4COX-2-IN-1
CAS:<p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>Formula:C18H14ClF3N4O2SPurity:>99.99%Color and Shape:SolidMolecular weight:442.84SC58451
CAS:<p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>Formula:C20H19FO2SPurity:>99.99%Color and Shape:SolidMolecular weight:342.43Insulin levels modulator
CAS:<p>Insulin level regulators can be used to treat diabetes.</p>Formula:C21H23N7OSPurity:98%Color and Shape:SolidMolecular weight:421.52Safrole oxide
CAS:<p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>Formula:C10H10O3Purity:100%Color and Shape:SolidMolecular weight:178.18COX-2-IN-21
CAS:<p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>Formula:C21H22N6O4Color and Shape:SolidMolecular weight:422.44COX-2/5-LOX-IN-1
CAS:<p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 & 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>Formula:C14H10ClN3O4S2Color and Shape:SolidMolecular weight:383.83APHS
CAS:<p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>Formula:C15H18O2SColor and Shape:SolidMolecular weight:262.37
