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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 561 products of "Cyclooxygenase (COX) Inhibitors"

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  • LY 25648

    CAS:
    <p>LY 25648 is an antagonist of leukotriene B4.</p>
    Formula:C19H27NO2S
    Color and Shape:Solid
    Molecular weight:333.49
  • ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Formula:C13H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.77
  • LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Formula:C13H14N2
    Color and Shape:Solid
    Molecular weight:198.26
  • PC407-ws

    CAS:
    <p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>
    Formula:C24H18F3N3Na2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:563.46
  • Isonixin

    CAS:
    <p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>
    Formula:C14H14N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:242.27
  • Tenosal

    CAS:
    <p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>
    Formula:C12H8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.25
  • LY 178002

    CAS:
    <p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>
    Formula:C18H25NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.46
  • L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Formula:C19H14Cl3NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.68
  • Eicosatetraynoic acid

    CAS:
    <p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>
    Formula:C20H24O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.4
  • Feprazone

    CAS:
    <p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>
    Formula:C20H20N2O2
    Purity:99.6% - 99.89%
    Color and Shape:Solid
    Molecular weight:320.39
  • Enflicoxib

    CAS:
    <p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>
    Formula:C16H12F5N3O2S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:405.34
  • Carpro-AM1

    CAS:
    <p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>
    Formula:C21H18ClN3O
    Color and Shape:Solid
    Molecular weight:363.84
  • Tilmacoxib

    CAS:
    <p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>
    Formula:C16H19FN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.4
  • COX-2-IN-1

    CAS:
    <p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>
    Formula:C18H14ClF3N4O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:442.84
  • SC58451

    CAS:
    <p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>
    Formula:C20H19FO2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:342.43
  • Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Formula:C21H23N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.52
  • Safrole oxide

    CAS:
    <p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>
    Formula:C10H10O3
    Purity:100%
    Color and Shape:Solid
    Molecular weight:178.18
  • COX-2-IN-21

    CAS:
    <p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>
    Formula:C21H22N6O4
    Color and Shape:Solid
    Molecular weight:422.44
  • COX-2/5-LOX-IN-1

    CAS:
    <p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 &amp; 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>
    Formula:C14H10ClN3O4S2
    Color and Shape:Solid
    Molecular weight:383.83
  • APHS

    CAS:
    <p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>
    Formula:C15H18O2S
    Color and Shape:Solid
    Molecular weight:262.37