CymitQuimica logo
Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • LM-1685

    CAS:
    <p>LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂,IC50分别为0.65 µM 和IC50 = 4.3 μM,是治疗炎症的潜在化合物。</p>
    Formula:C18H16ClNO4S
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:377.84
  • SC-75416

    CAS:
    <p>SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.</p>
    Formula:C15H14ClF3O3
    Purity:98.67% - 98.67%
    Color and Shape:Solid
    Molecular weight:334.72
  • BN-82451 2HCl

    CAS:
    <p>BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.</p>
    Formula:C18H28Cl2N2OS
    Purity:99.84% - >99.99%
    Color and Shape:Solid
    Molecular weight:391.4
  • Indazole-Cl

    CAS:
    <p>Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).</p>
    Formula:C13H9ClN2O2
    Purity:99.02% - 99.86%
    Color and Shape:Solid
    Molecular weight:260.68
  • Biofor 389

    CAS:
    <p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>
    Formula:C20H29NO3
    Purity:98.84% - 99.97%
    Color and Shape:Solid
    Molecular weight:331.45
  • L 651896

    CAS:
    <p>L 651896 is an inhibitor of 5-lipoxygenase.</p>
    Formula:C18H18O3
    Purity:96.06% - 99.85%
    Color and Shape:Solid
    Molecular weight:282.33
  • Prostaglandin E2 Ethanolamide

    CAS:
    <p>Prostaglandin E2 Ethanolamide (PGE 2 -EA), an analog of PGE2, is enzymatically synthesized through COX-2 oxygenation of endocannabinoids. It has the potential to modulate the production of the proinflammatory cytokine TNF-α in human blood and monocytic cells [1] [2].</p>
    Formula:C22H37NO5
    Color and Shape:Solid
    Molecular weight:395.54
  • Benoxaprofen

    CAS:
    <p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>
    Formula:C16H12ClNO3
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:301.72
  • BW 755C

    CAS:
    <p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>
    Formula:C10H10F3N3
    Purity:96.52%
    Color and Shape:Solid
    Molecular weight:229.2
  • Antioxidant agent-15

    CAS:
    <p>Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.</p>
    Formula:C19H14O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:274.31
  • Thioflosulide

    CAS:
    <p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>
    Formula:C16H13F2NO3S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:369.41
  • Thromboxane B3

    CAS:
    <p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>
    Formula:C20H32O6
    Color and Shape:Solid
    Molecular weight:368.5
  • Amtolmetin guacil

    CAS:
    <p>Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性,具有额外的镇痛、解热和胃保护特性。</p>
    Formula:C24H24N2O5
    Purity:99.85%
    Color and Shape:White Needle-Shaped Crystal
    Molecular weight:420.46
  • (-)-Bornyl ferulate

    CAS:
    <p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>
    Formula:C20H26O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:330.42
  • Cimicoxib

    CAS:
    <p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>
    Formula:C16H13ClFN3O3S
    Purity:98.22%
    Color and Shape:Solid
    Molecular weight:381.81
  • COX-2-IN-10


    <p>COX-2-IN-10 is a potent COX-2 inhibitor, reducing IL-6, TNF-α, IL-1β, PGE2 (IC50=2.54 μM), and iNOS expression.</p>
    Formula:C31H32FN5O2S
    Color and Shape:Solid
    Molecular weight:557.68
  • COX-2-IN-12


    <p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>
    Formula:C17H19NO3
    Color and Shape:Solid
    Molecular weight:285.34
  • COX-2-IN-13


    <p>COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.</p>
    Formula:C19H18N2O5S
    Color and Shape:Solid
    Molecular weight:386.42
  • COX-2-IN-8


    <p>COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.</p>
    Formula:C19H19N3O4S2
    Color and Shape:Solid
    Molecular weight:417.5
  • Anti-inflammatory agent 9


    <p>Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects &amp; is orally bioavailable.</p>
    Formula:C18H15N5O2S
    Color and Shape:Solid
    Molecular weight:365.41