
Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 562 products of "Cyclooxygenase (COX) Inhibitors"
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LM-1685
CAS:<p>LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂,IC50分别为0.65 µM 和IC50 = 4.3 μM,是治疗炎症的潜在化合物。</p>Formula:C18H16ClNO4SPurity:98.16%Color and Shape:SolidMolecular weight:377.84SC-75416
CAS:<p>SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.</p>Formula:C15H14ClF3O3Purity:98.67% - 98.67%Color and Shape:SolidMolecular weight:334.72BN-82451 2HCl
CAS:<p>BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.</p>Formula:C18H28Cl2N2OSPurity:99.84% - >99.99%Color and Shape:SolidMolecular weight:391.4Indazole-Cl
CAS:<p>Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).</p>Formula:C13H9ClN2O2Purity:99.02% - 99.86%Color and Shape:SolidMolecular weight:260.68Biofor 389
CAS:<p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>Formula:C20H29NO3Purity:98.84% - 99.97%Color and Shape:SolidMolecular weight:331.45L 651896
CAS:<p>L 651896 is an inhibitor of 5-lipoxygenase.</p>Formula:C18H18O3Purity:96.06% - 99.85%Color and Shape:SolidMolecular weight:282.33Prostaglandin E2 Ethanolamide
CAS:<p>Prostaglandin E2 Ethanolamide (PGE 2 -EA), an analog of PGE2, is enzymatically synthesized through COX-2 oxygenation of endocannabinoids. It has the potential to modulate the production of the proinflammatory cytokine TNF-α in human blood and monocytic cells [1] [2].</p>Formula:C22H37NO5Color and Shape:SolidMolecular weight:395.54Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72BW 755C
CAS:<p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>Formula:C10H10F3N3Purity:96.52%Color and Shape:SolidMolecular weight:229.2Antioxidant agent-15
CAS:<p>Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.</p>Formula:C19H14O2Purity:98%Color and Shape:SolidMolecular weight:274.31Thioflosulide
CAS:<p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>Formula:C16H13F2NO3S2Purity:>99.99%Color and Shape:SolidMolecular weight:369.41Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Formula:C20H32O6Color and Shape:SolidMolecular weight:368.5Amtolmetin guacil
CAS:<p>Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性,具有额外的镇痛、解热和胃保护特性。</p>Formula:C24H24N2O5Purity:99.85%Color and Shape:White Needle-Shaped CrystalMolecular weight:420.46(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Formula:C20H26O4Purity:98%Color and Shape:SolidMolecular weight:330.42Cimicoxib
CAS:<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Formula:C16H13ClFN3O3SPurity:98.22%Color and Shape:SolidMolecular weight:381.81COX-2-IN-10
<p>COX-2-IN-10 is a potent COX-2 inhibitor, reducing IL-6, TNF-α, IL-1β, PGE2 (IC50=2.54 μM), and iNOS expression.</p>Formula:C31H32FN5O2SColor and Shape:SolidMolecular weight:557.68COX-2-IN-12
<p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>Formula:C17H19NO3Color and Shape:SolidMolecular weight:285.34COX-2-IN-13
<p>COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.</p>Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42COX-2-IN-8
<p>COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.</p>Formula:C19H19N3O4S2Color and Shape:SolidMolecular weight:417.5Anti-inflammatory agent 9
<p>Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.</p>Formula:C18H15N5O2SColor and Shape:SolidMolecular weight:365.41

