Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 600 products of "Cyclooxygenase (COX) Inhibitors"
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ZXX2-77
CAS:ZXX2-77 is a cyclooxygenase-1 inhibitor.Formula:C13H13ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:296.77COX-2-IN-1
CAS:COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).Formula:C18H14ClF3N4O2SPurity:>99.99%Color and Shape:SolidMolecular weight:442.84Ref: TM-T10033
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)283.00€COX-2-IN-20
CAS:COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].Formula:C11H9ClFN3O2Color and Shape:SolidMolecular weight:269.66Carpro-AM1
CAS:Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.Formula:C21H18ClN3OColor and Shape:SolidMolecular weight:363.84LY 150310
CAS:LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26CAY10416
CAS:CAY10416: dual COX-2/5-LO inhibitor, IC50: COX-2 (50 nM), 5-LO (3 nM); >200x selectivity for COX-2; anti-inflammatory, prostate cancer agent.Formula:C29H29FN2O5SColor and Shape:SolidMolecular weight:536.61COX-2-IN-28
CAS:COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).Formula:C30H27N7S3Color and Shape:SolidMolecular weight:581.78Insulin levels modulator
CAS:Insulin level regulators can be used to treat diabetes.Formula:C21H23N7OSPurity:98%Color and Shape:SolidMolecular weight:421.52L 748780
CAS:L 748780 is a selective inducible COX-2 inhibitor.Formula:C19H14Cl3NO4Purity:98%Color and Shape:SolidMolecular weight:426.68Enflicoxib
CAS:Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.Formula:C16H12F5N3O2SPurity:99.88%Color and Shape:SolidMolecular weight:405.34SC58451
CAS:SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.Formula:C20H19FO2SPurity:>99.99%Color and Shape:SolidMolecular weight:342.43COX-2-IN-21
CAS:COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.Formula:C21H22N6O4Color and Shape:SolidMolecular weight:422.44APHS
CAS:APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.Formula:C15H18O2SColor and Shape:SolidMolecular weight:262.37Safrole oxide
CAS:Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.Formula:C10H10O3Purity:100%Color and Shape:SolidMolecular weight:178.18(-)-Ibuprofenamide
CAS:(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.Formula:C13H19NOPurity:98%Color and Shape:SolidMolecular weight:205.3Piroxicam cinnamate
CAS:Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.Formula:C24H19N3O5SColor and Shape:SolidMolecular weight:461.49GW-406381
CAS:GW-406381 is a highly selective COX-2 inhibitor peripherally and centrally, reducing spontaneous ectopic discharges following chronic compressive injury.Formula:C21H19N3O3SPurity:99.54%Color and Shape:SolidMolecular weight:393.46COX-2/5-LOX-IN-2
CAS:COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.Formula:C18H13N3O4S2Color and Shape:SolidMolecular weight:399.44Heterophdoid A
CAS:Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).Formula:C26H42O10Color and Shape:SolidMolecular weight:514.61COX-2-IN-11
CAS:COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].Formula:C12H12OS3Color and Shape:SolidMolecular weight:268.42
