GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 265 products of "GluR"
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CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Formula:C13H13NO4Purity:97.37%Color and Shape:SolidMolecular weight:247.25Ref: TM-T19698
5mg52.00€1mL*10mM (DMSO)55.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€200mg388.00€MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Formula:C11H8N2SColor and Shape:SolidMolecular weight:200.26JNJ-42153605
CAS:JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).Formula:C22H23F3N4Purity:97.25% - 98.57%Color and Shape:SolidMolecular weight:400.44Ref: TM-T3451
2mg34.00€5mg54.00€1mL*10mM (DMSO)55.00€10mg78.00€25mg124.00€50mg185.00€100mg263.00€200mg369.00€LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46Ref: TM-T7706
2mg35.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg90.00€25mg164.00€50mg239.00€100mg339.00€200mg472.00€CX717
CAS:CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.Formula:C11H11N3O3Purity:99.81%Color and Shape:SoildMolecular weight:233.23(S)-4CPG
CAS:(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.Formula:C9H9NO4Purity:99.96%Color and Shape:SolidMolecular weight:195.17VU0477886
CAS:VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.Formula:C20H13ClN4O3Purity:98%Color and Shape:SolidMolecular weight:392.80IEM 1754 2HBr
CAS:IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.Formula:C16H30N2·2HBrPurity:99.04% - 99.72%Color and Shape:SolidMolecular weight:412.25LY456066
CAS:LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.Formula:C19H23N3OSPurity:98%Color and Shape:SolidMolecular weight:341.47Methoxy-PEPy
CAS:Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.Formula:C13H10N2OPurity:98.66%Color and Shape:SolidMolecular weight:210.23Z-Cyclopentyl-AP4
CAS:Group III mGlu receptor agonistFormula:C6H12NO5PPurity:98%Color and Shape:SolidMolecular weight:209.14Talaglumetad hydrochloride
CAS:Talaglumetad hydrochloride, a prodrug of Eglumegad, targets mGluR2/3 to treat psychiatric disorders.Formula:C11H17ClN2O5Color and Shape:SolidMolecular weight:292.72DFMTI
CAS:DFMTI can completely block the rmGlu1 L757V glutamate response.Formula:C20H18F2N4OColor and Shape:SolidMolecular weight:368.38LY392098
CAS:LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.Formula:C18H22FNO2SPurity:99.86%Color and Shape:SolidMolecular weight:335.44Ref: TM-T27951
1mg39.00€5mg93.00€1mL*10mM (DMSO)96.00€10mg133.00€25mg215.00€50mg306.00€100mg414.00€200mg573.00€RO5488608
CAS:RO5488608 is a new type of high-efficiency mGlu2/3 NAM.Formula:C23H17F3N2O4SColor and Shape:SolidMolecular weight:474.45GRN-529
CAS:GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.Formula:C22H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:391.37A 841720
CAS:Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.Formula:C17H21N5OSColor and Shape:SolidMolecular weight:343.45NPEC-caged-LY379268
CAS:NPEC-caged-LY379268 is a type II mGluR agonist [1].Formula:C16H16N2O9Color and Shape:SolidMolecular weight:380.31MAP4
CAS:metabotropic glutamate receptor modulatorFormula:C5H12NO5PPurity:98%Color and Shape:White SolidMolecular weight:197.13mGluR2 modulator 1
CAS:Potent mGluR2 modulator 1 crosses blood-brain barrier, EC50: 0.03 μM, useful for psychiatric research.Formula:C21H20F3N3O3Color and Shape:SolidMolecular weight:419.4
