GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 261 products of "GluR"
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LY 541850
CAS:LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from humanFormula:C9H13NO4Purity:98%Color and Shape:SolidMolecular weight:199.2CVN636
CAS:CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for humanFormula:C19H20FNO4SColor and Shape:SolidMolecular weight:377.43LY2979165
CAS:LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.Formula:C13H22N6O6SPurity:98.41%Color and Shape:SolidMolecular weight:390.42Eglumegad
CAS:Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).Formula:C8H11NO4Color and Shape:SolidMolecular weight:185.18(RS)-APICA
CAS:group II metabotropic glutamate receptor antagonistFormula:C10H12NO5PColor and Shape:SolidMolecular weight:257.18YM-298198 hydrochloride
CAS:mGlu1 receptor antagonistFormula:C18H23ClN4OSPurity:98%Color and Shape:SolidMolecular weight:378.919Eglumegad hydrochloride
Eglumegad (LY354740) hydrochloride is a potent, selective agonist for group II (mGlu2/3) receptors, showing IC50 values of 5 nM for mGlu2 and 24 nM for mGlu3 receptors in transfected human cells. This compound provides neuroprotection against NMDA-induced toxicity and exhibits anxiolytic- and antipsychotic-like properties [1].Formula:C8H12ClNO4Color and Shape:SolidMolecular weight:221.64VU0080241
CAS:VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).Formula:C19H23N5Color and Shape:SolidMolecular weight:321.42CMPDA
CAS:CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].Formula:C16H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:376.53YM 298198 Hydrochloride
CAS:YM 298198 HCl: non-competitive mGlu1 antagonist, Ki=19 nM. Inactive on mGlu2-7, stronger than CPCCOEt.Formula:C18H22N4OSColor and Shape:SolidMolecular weight:342.46UBP1112
CAS:group III mGlu receptor antagonistFormula:C10H14NO5PPurity:98%Color and Shape:SolidMolecular weight:259.2
