GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(S)-4CPG
CAS:<p>(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.</p>Formula:C9H9NO4Purity:99.96%Color and Shape:SolidMolecular weight:195.17CX717
CAS:<p>CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.</p>Formula:C11H11N3O3Purity:99.81%Color and Shape:SoildMolecular weight:233.23VU0477886
CAS:<p>VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.</p>Formula:C20H13ClN4O3Purity:98%Color and Shape:SolidMolecular weight:392.80IEM 1754 2HBr
CAS:<p>IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.</p>Formula:C16H30N2·2HBrPurity:99.71% - 99.72%Color and Shape:SolidMolecular weight:412.25VU6001966
CAS:<p>VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.</p>Formula:C17H15FN4O2Purity:98%Color and Shape:SolidMolecular weight:326.33BMT-145027
CAS:<p>BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).</p>Formula:C23H14ClF3N4Purity:99.62%Color and Shape:SolidMolecular weight:438.83MFZ 10-7 hydrochloride
CAS:<p>MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM</p>Formula:C15H10ClFN2Purity:98%Color and Shape:SolidMolecular weight:272.71NS 1209
CAS:<p>NS 1209 (SPD 502) is a AMPA receptor antagonist.</p>Formula:C24H27N4NaO7SPurity:98%Color and Shape:SolidMolecular weight:538.55LY392098
CAS:<p>LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.</p>Formula:C18H22FNO2SPurity:99.86%Color and Shape:SolidMolecular weight:335.44VU 0469650
CAS:<p>VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).</p>Formula:C22H28N4OPurity:98.03%Color and Shape:SolidMolecular weight:364.48(1R,2S)-VU0155041
CAS:<p>(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.</p>Formula:C14H15Cl2NO3Purity:98.85%Color and Shape:SolidMolecular weight:316.18Methoxy-PEPy
CAS:<p>Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.</p>Formula:C13H10N2OPurity:99.22%Color and Shape:SolidMolecular weight:210.23LYPLAL1-IN-1
CAS:<p>LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production.</p>Formula:C29H29N7O4Purity:98%Color and Shape:SolidMolecular weight:539.59(RS)-MCPG disodium salt
CAS:<p>group I/group II metabotropic glutamate receptor antagonist</p>Formula:C10H11NNaO4Purity:98%Color and Shape:SolidMolecular weight:232.193,3'-Difluorobenzaldazine
CAS:<p>allosteric potentiator of mGlu5</p>Formula:C14H10F2N2Purity:98%Color and Shape:SolidMolecular weight:244.24VU0366248
CAS:<p>VU0366248 is a mGlu5 negative allosteric modulator.</p>Formula:C14H7ClF2N2OPurity:98%Color and Shape:SolidMolecular weight:292.67L-AP4 monohydrate
CAS:<p>L-AP4 (L-APB) is a group III mGluR agonist with EC50s: 0.13μM (mGlu4), 0.29μM (mGlu8), 1.0μM (mGlu6), 249μM (mGlu7).</p>Formula:C4H12NO6PColor and Shape:SolidMolecular weight:201.115VU 0360223
CAS:<p>VU 0360223 is a negative allosteric modulator of mGlu5.</p>Formula:C15H9FN2SPurity:98%Color and Shape:SolidMolecular weight:268.31ADX71743
CAS:<p>ADX71743 is a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7.</p>Formula:C17H19NO2Color and Shape:SolidMolecular weight:269.34mGlu4 receptor agonist 1
CAS:<p>Compound 62, an mGlu4 agonist, has a 308 nM EC50 with anxiolytic and antipsychotic effects.</p>Formula:C21H15ClN4O2Color and Shape:SolidMolecular weight:390.82MAP4
CAS:<p>metabotropic glutamate receptor modulator</p>Formula:C5H12NO5PPurity:98%Color and Shape:White SolidMolecular weight:197.13GRN-529
CAS:<p>GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.</p>Formula:C22H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:391.37DFMTI
CAS:<p>DFMTI can completely block the rmGlu1 L757V glutamate response.</p>Formula:C20H18F2N4OColor and Shape:SolidMolecular weight:368.38Z-Cyclopentyl-AP4
CAS:<p>Group III mGlu receptor agonist</p>Formula:C6H12NO5PPurity:98%Color and Shape:SolidMolecular weight:209.14LY456066
CAS:<p>LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.</p>Formula:C19H23N3OSPurity:98%Color and Shape:SolidMolecular weight:341.47JNJ-40068782
CAS:<p>JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.</p>Formula:C21H23N3OPurity:98%Color and Shape:SolidMolecular weight:333.43TASP0433864
CAS:<p>TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.</p>Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39(S)-3,5-DHPG
CAS:<p>group I mGlu receptor agonist</p>Formula:C8H9NO4Purity:98%Color and Shape:SolidMolecular weight:183.16HTL14242
CAS:<p>HTL14242 is a mGlu5 Negative Allosteric Modulator.</p>Formula:C16H8ClFN4Color and Shape:SolidMolecular weight:310.71(RS)-PPG
CAS:<p>(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.</p>Formula:C8H10NO5PPurity:98%Color and Shape:SolidMolecular weight:231.14VU0431316
CAS:<p>VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.</p>Formula:C14H9ClN6O2Purity:98%Color and Shape:SolidMolecular weight:328.71DCG-IV
CAS:<p>DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.</p>Formula:C7H9NO6Purity:98%Color and Shape:SolidMolecular weight:203.15VU0410425
CAS:<p>VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.</p>Formula:C19H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:369.8AZ12216052
CAS:<p>AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35LY487379 hydrochloride
CAS:<p>Positive allosteric modulator of mGlu2 receptors</p>Formula:C21H20ClF3N2O4SPurity:98%Color and Shape:SolidMolecular weight:488.91VU0361747
CAS:<p>VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).</p>Formula:C19H17FN2O2Color and Shape:SolidMolecular weight:324.35Auglurant
CAS:<p>Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.</p>Formula:C16H12FN5O2Color and Shape:SolidMolecular weight:325.3Desmethyl-YM 298198
CAS:<p>mGlu1-selective antagonist</p>Formula:C17H21ClN4OSPurity:98%Color and Shape:SolidMolecular weight:364.89Foliglurax monohydrochloride
CAS:<p>Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.</p>Formula:C23H24ClN3O3SColor and Shape:SolidMolecular weight:457.97L-CCG-l
CAS:<p>group II metabotropic glutamate receptor agonist</p>Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14(1S,3R)-ACPD
CAS:<p>(1S,3R)-ACPD is a group I and II mGlu receptor agonist.</p>Formula:C7H11NO4Purity:98%Color and Shape:SolidMolecular weight:173.17VU0404251
CAS:<p>VU0404251 is a positive allosteric modulator of mGlu5.</p>Formula:C19H23FN2O2Color and Shape:SolidMolecular weight:330.4Mavoglurant racemate
CAS:<p>Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.</p>Formula:C19H23NO3Purity:98%Color and Shape:SolidMolecular weight:313.39ACPT-II
CAS:<p>metabotropic receptor antagonist</p>Formula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18DL-AP4 Sodium salt
CAS:<p>Broad spectrum EAA ligand</p>Formula:C4H10NNaO5PPurity:98%Color and Shape:SolidMolecular weight:206.09UPF-523
CAS:<p>group I metabotropic glutamate receptors (mGlu1a) antagonist</p>Formula:C11H11NO4Purity:98%Color and Shape:White SolidMolecular weight:221.21JNJ-46356479
CAS:<p>JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.</p>Formula:C22H22F5N5Color and Shape:SolidMolecular weight:451.44ACPT-I
CAS:<p>Agonist for group III mGlu receptors</p>Formula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18VU0364289
CAS:<p>VU0364289 is a positive allosteric modulator of mGlu5.</p>Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4(S)-4C3HPG
CAS:<p>group I mGlu1a/1a receptor antagonist and mGluR2 agonist</p>Formula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17
