GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 265 products of "GluR"
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ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Formula:C20H17F2N3O2Purity:97% - 99.22%Color and Shape:SolidMolecular weight:369.36JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Formula:C20H23NO3Purity:98.31%Color and Shape:SolidMolecular weight:325.4Ref: TM-T5512
1mg46.00€2mg62.00€5mg95.00€1mL*10mM (DMSO)95.00€10mg133.00€25mg278.00€50mg424.00€100mg620.00€PHCCC
CAS:PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.Formula:C17H14N2O3Purity:>99.99%Color and Shape:SolidMolecular weight:294.3YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66Ref: TM-T8435
1mg73.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€CX717
CAS:CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.Formula:C11H11N3O3Purity:99.81%Color and Shape:SoildMolecular weight:233.23(S)-4CPG
CAS:(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.Formula:C9H9NO4Purity:99.96%Color and Shape:SolidMolecular weight:195.17VU0477886
CAS:VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.Formula:C20H13ClN4O3Purity:98%Color and Shape:SolidMolecular weight:392.80IEM 1754 2HBr
CAS:IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.Formula:C16H30N2·2HBrPurity:99.04% - 99.72%Color and Shape:SolidMolecular weight:412.25(S)-4C3HPG
CAS:group I mGlu1a/1a receptor antagonist and mGluR2 agonistFormula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17ACPT-I
CAS:Agonist for group III mGlu receptorsFormula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18JNJ-46356479
CAS:JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.Formula:C22H22F5N5Color and Shape:SolidMolecular weight:451.44LSN2814617
CAS:LSN2814617: oral, brain-penetrant mGlu5 PAM, EC50 = 52 nM (human), 42 nM (rat). Promotes wakefulness, useful in schizophrenia study.Formula:C18H20FN5OPurity:98%Color and Shape:SolidMolecular weight:341.38RO4988546
CAS:RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.Formula:C21H10F6N4O3SPurity:98%Color and Shape:SolidMolecular weight:512.38mGluR2 modulator 1
CAS:Potent mGluR2 modulator 1 crosses blood-brain barrier, EC50: 0.03 μM, useful for psychiatric research.Formula:C21H20F3N3O3Color and Shape:SolidMolecular weight:419.4NPEC-caged-LY379268
CAS:NPEC-caged-LY379268 is a type II mGluR agonist [1].Formula:C16H16N2O9Color and Shape:SolidMolecular weight:380.31A 841720
CAS:Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.Formula:C17H21N5OSColor and Shape:SolidMolecular weight:343.45RO5488608
CAS:RO5488608 is a new type of high-efficiency mGlu2/3 NAM.Formula:C23H17F3N2O4SColor and Shape:SolidMolecular weight:474.45Talaglumetad hydrochloride
CAS:Talaglumetad hydrochloride, a prodrug of Eglumegad, targets mGluR2/3 to treat psychiatric disorders.Formula:C11H17ClN2O5Color and Shape:SolidMolecular weight:292.72mGluR2 modulator 2
CAS:mGluR2 modulator 2: potent, selective, oral, EC50 = 0.13 μM, for antipsychotic research.Formula:C20H22FN3Color and Shape:SolidMolecular weight:323.41UPF-523
CAS:group I metabotropic glutamate receptors (mGlu1a) antagonistFormula:C11H11NO4Purity:98%Color and Shape:White SolidMolecular weight:221.21VU0418506
CAS:VU0418506 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGlu4).Formula:C12H8ClFN4Purity:98%Color and Shape:SolidMolecular weight:262.67ACDPP hydrochloride
CAS:mGlu5 receptor antagonistFormula:C12H13ClN6OPurity:98%Color and Shape:SolidMolecular weight:292.72Ro 64-5229
CAS:mGlu2 antagonistFormula:C17H19Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:352.26DL-AP4 Sodium salt
CAS:Broad spectrum EAA ligandFormula:C4H10NNaO5PPurity:98%Color and Shape:SolidMolecular weight:206.09VU6001966
CAS:VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.Formula:C17H15FN4O2Purity:98%Color and Shape:SolidMolecular weight:326.33VU6010572
CAS:VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.Formula:C20H18FNO3Color and Shape:SolidMolecular weight:339.36VU0463841
CAS:VU0463841 is a mGlu5 negative allosteric modulators.Formula:C13H8ClFN4OColor and Shape:SolidMolecular weight:290.68VU 0360172 hydrochloride
CAS:positive allosteric modulator of mGlu5 receptorsFormula:C18H16ClFN2OPurity:98%Color and Shape:SolidMolecular weight:330.78ACPT-II
CAS:metabotropic receptor antagonistFormula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18mGluR2 modulator 4
CAS:Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.Formula:C18H18BrN3Color and Shape:SolidMolecular weight:356.26VU0400195
CAS:VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).Formula:C21H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:393.82VU0404251
CAS:VU0404251 is a positive allosteric modulator of mGlu5.Formula:C19H23FN2O2Color and Shape:SolidMolecular weight:330.4VU0364289
CAS:VU0364289 is a positive allosteric modulator of mGlu5.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4VU0361747
CAS:VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).Formula:C19H17FN2O2Color and Shape:SolidMolecular weight:324.35MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Formula:C4H10NO6PPurity:98%Color and Shape:SolidMolecular weight:199.1LY487379 hydrochloride
CAS:Positive allosteric modulator of mGlu2 receptorsFormula:C21H20ClF3N2O4SPurity:98%Color and Shape:SolidMolecular weight:488.91AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35CFMMC
CAS:CFMMC is an allosteric mGluR1 antagonist agent.
Formula:C22H28FNO4Color and Shape:SolidMolecular weight:389.46YM 230888
CAS:Selective mGlu1 antagonistFormula:C19H28N4OSPurity:98%Color and Shape:SolidMolecular weight:360.52LY2607540
CAS:LY2607540 is a metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties (EC(50) = 23 and 13 nM, respectively).Formula:C24H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:475.46VU0410425
CAS:VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.Formula:C19H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:369.8(S)-HexylHIBO
CAS:Group I mGlu receptor antagonistFormula:C12H20N2O4Purity:98%Color and Shape:SolidMolecular weight:256.3LSP1-2111
CAS:LSP1-2111 is a mGlu4 receptor subtype agonist.Formula:C12H17N2O9PColor and Shape:SolidMolecular weight:364.25Lu-AF11205
CAS:Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor.Formula:C17H16N2OSPurity:98%Color and Shape:SolidMolecular weight:296.39(RS)-4-Carboxyphenylglycine
CAS:(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.Formula:C9H9NO4Purity:97.22% - >99.99%Color and Shape:SolidMolecular weight:195.17(R)-4-Carboxyphenylglycine
CAS:(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist.Formula:C9H9NO4Purity:98%Color and Shape:SolidMolecular weight:195.17DCG-IV
CAS:DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.Formula:C7H9NO6Purity:98%Color and Shape:SolidMolecular weight:203.15VU0652835
CAS:VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).Formula:C16H19N3O3SPurity:98%Color and Shape:SolidMolecular weight:333.41VU0486321
CAS:VU0486321: potent mGlu1 PAM, rat PK CLp 13.3 mL/min/kg, t1/2 54 min, human fu 0.05, rat fu 0.03, great CNS penetration Kp 1.02.Formula:C20H12ClFN2O4Color and Shape:SolidMolecular weight:398.77A-850002
CAS:A-850002 is a bioactive chemical.Formula:C18H16N4OSColor and Shape:SolidMolecular weight:336.41
