GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 263 products for "GluR".
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HexylHIBO
CAS:HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.Formula:C12H20N2O4Purity:99.55%Color and Shape:SolidMolecular weight:256.3(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20(1R,2S)-VU0155041
CAS:(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.Formula:C14H15Cl2NO3Purity:98.85%Color and Shape:SolidMolecular weight:316.18TC-N 22A
CAS:TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.Formula:C14H13N5SPurity:99.95%Color and Shape:Orange SolidMolecular weight:283.35BMT-145027
CAS:BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).Formula:C23H14ClF3N4Purity:99.62%Color and Shape:White SolidMolecular weight:438.83DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Formula:C16H16N2O2Purity:99.84%Color and Shape:SolidMolecular weight:268.31TASP0433864
CAS:TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39(S)-3,5-DHPG
CAS:group I mGlu receptor agonistFormula:C8H9NO4Purity:99.60%Color and Shape:White SolidMolecular weight:183.16HTL14242
CAS:HTL14242 is a mGlu5 Negative Allosteric Modulator.Formula:C16H8ClFN4Color and Shape:SolidMolecular weight:310.71JNJ-40068782
CAS:JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.Formula:C21H23N3OPurity:98%Color and Shape:SolidMolecular weight:333.43(RS)-PPG
CAS:(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.Formula:C8H10NO5PPurity:98%Color and Shape:SolidMolecular weight:231.14CPPHA
CAS:CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.Formula:C22H15ClN2O4Purity:99.7%Color and Shape:White SolidMolecular weight:406.82VU0431316
CAS:VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.Formula:C14H9ClN6O2Purity:98%Color and Shape:SolidMolecular weight:328.71DCG-IV
CAS:DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.Formula:C7H9NO6Purity:98%Color and Shape:SolidMolecular weight:203.15VU0410425
CAS:VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.Formula:C19H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:369.8LY456066
CAS:LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.Formula:C19H23N3OSPurity:98%Color and Shape:SolidMolecular weight:341.47AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Formula:C19H22BrNOSPurity:99.78%Color and Shape:SolidMolecular weight:392.35LY487379 hydrochloride
CAS:Positive allosteric modulator of mGlu2 receptorsFormula:C21H20ClF3N2O4SPurity:98%Color and Shape:SolidMolecular weight:488.91VU0361747
CAS:VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).Formula:C19H17FN2O2Color and Shape:SolidMolecular weight:324.35Auglurant
CAS:Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.Formula:C16H12FN5O2Color and Shape:SolidMolecular weight:325.3Desmethyl-YM 298198
CAS:mGlu1-selective antagonistFormula:C17H21ClN4OSPurity:98%Color and Shape:SolidMolecular weight:364.89Foliglurax monohydrochloride
CAS:Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.Formula:C23H24ClN3O3SColor and Shape:SolidMolecular weight:457.97L-CCG-l
CAS:group II metabotropic glutamate receptor agonistFormula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14(1S,3R)-ACPD
CAS:(1S,3R)-ACPD is a group I and II mGlu receptor agonist.Formula:C7H11NO4Purity:98%Color and Shape:SolidMolecular weight:173.17VU0404251
CAS:VU0404251 is a positive allosteric modulator of mGlu5.Formula:C19H23FN2O2Color and Shape:SolidMolecular weight:330.4Mavoglurant racemate
CAS:Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.Formula:C19H23NO3Purity:98%Color and Shape:SolidMolecular weight:313.39ACPT-II
CAS:metabotropic receptor antagonistFormula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18Z-Cyclopentyl-AP4
CAS:Group III mGlu receptor agonistFormula:C6H12NO5PPurity:98%Color and Shape:SolidMolecular weight:209.14DFMTI
CAS:DFMTI can completely block the rmGlu1 L757V glutamate response.Formula:C20H18F2N4OColor and Shape:SolidMolecular weight:368.38DL-AP4 Sodium salt
CAS:Broad spectrum EAA ligandFormula:C4H10NNaO5PPurity:98%Color and Shape:SolidMolecular weight:206.09GRN-529
CAS:GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.Formula:C22H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:391.37MAP4
CAS:metabotropic glutamate receptor modulatorFormula:C5H12NO5PPurity:98%Color and Shape:SolidMolecular weight:197.13UPF-523
CAS:group I metabotropic glutamate receptors (mGlu1a) antagonistFormula:C11H11NO4Purity:98%Color and Shape:White SolidMolecular weight:221.21JNJ-46356479
CAS:JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.Formula:C22H22F5N5Color and Shape:SolidMolecular weight:451.44ACPT-I
CAS:Agonist for group III mGlu receptorsFormula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18mGluR2 modulator 4
CAS:Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.Formula:C18H18BrN3Color and Shape:SolidMolecular weight:356.26VU0400195
CAS:VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).Formula:C21H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:393.82(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:broad spectrum EAA agonist/antagonistFormula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17Ro4491533
CAS:Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).Formula:C24H20F3N3OColor and Shape:SolidMolecular weight:423.43MMPIP
CAS:allosteric mGlu7-selective receptor antagonistFormula:C19H15N3O3Purity:98%Color and Shape:SolidMolecular weight:333.34LSP4-2022
CAS:LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.Formula:C13H18NO8PPurity:100%Color and Shape:White SolidMolecular weight:347.26VU0409106
CAS:VU0409106 is a selective mGlu5 negative allosteric modulator with anxiolytic effects.Formula:C15H11FN4O2SPurity:99.89%Color and Shape:White SolidMolecular weight:330.34Remeglurant
CAS:Remeglurant is used as a selective antagonist of the mGlu5 receptor.Formula:C17H15BrN4OColor and Shape:SolidMolecular weight:371.23IEM 1925 dihydrobromide
CAS:AMPA receptor antagonistFormula:C17H30Br2N2Purity:98%Color and Shape:SolidMolecular weight:422.24PHCCC(4Me)
CAS:THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.Formula:C18H16N2O3Color and Shape:SolidMolecular weight:308.33VU0366248
CAS:VU0366248 is a mGlu5 negative allosteric modulator.Formula:C14H7ClF2N2OPurity:98%Color and Shape:SolidMolecular weight:292.673,3'-Difluorobenzaldazine
CAS:allosteric potentiator of mGlu5Formula:C14H10F2N2Purity:98%Color and Shape:SolidMolecular weight:244.24VU 0469650
CAS:VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).Formula:C22H28N4OPurity:98.03%Color and Shape:SolidMolecular weight:364.48Ref: TM-T29118
1mg42.00€5mg79.00€1mL*10mM (DMSO)90.00€10mg108.00€25mg210.00€50mg313.00€100mg464.00€200mg640.00€(RS)-MCPG disodium salt
CAS:group I/group II metabotropic glutamate receptor antagonistFormula:C10H11NNaO4Purity:98%Color and Shape:SolidMolecular weight:232.19MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Formula:C4H10NO6PPurity:98%Color and Shape:SolidMolecular weight:199.1
