AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
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Biricodar dicitrate
CAS:<p>Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.</p>Formula:C46H57N3O21Purity:97.78% - 99.78%Color and Shape:SolidMolecular weight:987.95Sofiniclin
CAS:<p>Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).</p>Formula:C10H11Cl2N3Purity:98%Color and Shape:SolidMolecular weight:244.12Bibn 99
CAS:<p>Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.</p>Formula:C31H42ClN5O3Color and Shape:SolidMolecular weight:568.15VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Formula:C24H17ClF2N2O2Purity:98%Color and Shape:SolidMolecular weight:438.85Rivanicline
CAS:<p>Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.</p>Formula:C10H14N2Purity:98%Color and Shape:SolidMolecular weight:162.23Rapacuronium bromide
CAS:<p>Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.</p>Formula:C37H61BrN2O4Purity:98%Color and Shape:SolidMolecular weight:677.8ML375
CAS:<p>ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).</p>Formula:C23H15ClF2N2O2Color and Shape:SolidMolecular weight:424.83CP-601927
CAS:<p>CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.</p>Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23Arecaidine propargyl ester tosylate
CAS:<p>Arecaidine propargyl ester tosylate is a muscarinic receptor agonist.</p>Formula:C17H21NO5SPurity:98%Color and Shape:SolidMolecular weight:351.42VMY-2-95
CAS:<p>VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.</p>Formula:C17H16N2OColor and Shape:SolidMolecular weight:264.32RJR 2429 dihydrochloride
CAS:<p>nAChR agonist that displays selectivity for α4β2</p>Formula:C12H18Cl2N2Purity:98%Color and Shape:SolidMolecular weight:261.19J 104129 fumarate
CAS:<p>M3 muscarinic receptor antagonist</p>Formula:C24H36N2O2Purity:98%Color and Shape:SolidMolecular weight:384.55Alvameline maleate
CAS:<p>Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.</p>Formula:C13H19N5O4Color and Shape:SolidMolecular weight:309.32Vinconate
CAS:<p>Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.</p>Formula:C18H20N2O2Purity:98%Color and Shape:SolidMolecular weight:296.36AT-1001
CAS:<p>AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.</p>Formula:C15H21BrN2Color and Shape:SolidMolecular weight:309.24Rivanicline oxalate
CAS:<p>Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).</p>Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:252.27Bradanicline HCl
CAS:<p>Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.</p>Formula:C22H24ClN3O2Color and Shape:SolidMolecular weight:397.9DREADD agonist 21 dihydrochloride
CAS:<p>DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].</p>Formula:C17H20Cl2N4Purity:98%Color and Shape:SolidMolecular weight:351.27BPIPP
CAS:<p>guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor</p>Formula:C22H16BrN3O3Purity:98%Color and Shape:SolidMolecular weight:450.28Procyclidine
CAS:<p>Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.</p>Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Oxybutynin R-isomer HCl
CAS:<p>Aroxybutynin, R-isomer of oxybutynin, is a muscarinic antagonist with antispasmodic effects on bladder muscle, weaker than atropine.</p>Formula:C22H32ClNO3Color and Shape:SolidMolecular weight:393.95VU0455691
CAS:<p>VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.</p>Formula:C24H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:463.55Ambutonium bromide
CAS:<p>Ambutonium bromide is an antagonist of acetylcholine.</p>Formula:C20H27BrN2OPurity:98%Color and Shape:SolidMolecular weight:391.35(±)-Muscarine chloride
CAS:<p>(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].</p>Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71Methapyrilene
CAS:<p>Methapyrilene is a histamine H1 antagonist with sedative action.</p>Formula:C14H19N3SColor and Shape:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:261.39Milameline hydrochloride
CAS:<p>Milameline hydrochloride is a Muscarinic receptor agonist.</p>Formula:C8H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:190.67Cycrimine
CAS:<p>Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.</p>Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Parapenzolate bromide
CAS:<p>Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.</p>Formula:C21H26BrNO3Color and Shape:SolidMolecular weight:420.347DPNB-ABT594
<p>DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.</p>Formula:C31H46ClN3O11Color and Shape:SolidMolecular weight:672.16AFDX384
CAS:<p>AFDX384 is potent M2/M4 selective antagonist.</p>Formula:C28H42N6O5SColor and Shape:SolidMolecular weight:574.74(S)-VQW-765
<p>(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.</p>Formula:C19H22N2OColor and Shape:SolidMolecular weight:294.39Mazaticol
CAS:<p>Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.</p>Formula:C21H27NO3S2Color and Shape:SolidMolecular weight:405.57J-104129 fumarate
CAS:<p>J-104129 fumarate is a potent M3 muscarinic receptor antagonist.</p>Formula:C28H40N2O6Color and Shape:SolidMolecular weight:500.63BMS-902483
CAS:<p>BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.</p>Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38RLH 033
CAS:<p>RLH 033 is a selective ligand for the sigma 1 recognition site.</p>Formula:C25H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:458.98Talsaclidine
CAS:<p>Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.</p>Formula:C10H15NOPurity:98%Color and Shape:SolidMolecular weight:165.23A-85380 HCl
CAS:<p>A-85380 is an agonist of nicotinic acetylcholine receptor.</p>Formula:C9H14Cl2N2OColor and Shape:SolidMolecular weight:237.13Phenglutarimid
CAS:<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Formula:C17H24N2O2Purity:98%Color and Shape:SolidMolecular weight:288.38Pirenzepine
CAS:<p>Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.</p>Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4ENS-163 phosphate
CAS:<p>Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.</p>Formula:C11H19N2O5PSPurity:98%Color and Shape:SolidMolecular weight:322.32TMPH hydrochloride
CAS:<p>neuronal nicotinic ACh receptors (nAChRs) antagonist</p>Formula:C16H32ClNO2Purity:98%Color and Shape:SolidMolecular weight:305.889-CP-Ade Mesylate
CAS:<p>9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.</p>Formula:C11H17N5O3SPurity:99.81%Color and Shape:SolidMolecular weight:299.35Arecaidine but-2-ynyl ester tosylate
CAS:<p>mAChR M2 agonist</p>Formula:C18H23NO5SPurity:98%Color and Shape:SolidMolecular weight:365.44GSK575594A
CAS:<p>GSK575594A is a selective agonist of GPR55.</p>Formula:C24H23F2N3O3SColor and Shape:SolidMolecular weight:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Formula:C22H31NO3Color and Shape:SolidMolecular weight:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Formula:C20H31NOColor and Shape:SolidMolecular weight:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:<p>α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).</p>Formula:C25H30O6Color and Shape:SolidMolecular weight:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Formula:C22H27NOPurity:98%Color and Shape:SolidMolecular weight:321.46Anabasine hydrochloride
CAS:<p>neuronal nicotinic ACh receptor partial agonist</p>Formula:C10H15ClN2Purity:98%Color and Shape:White To Off-White SolidMolecular weight:198.693Flupyrimin
CAS:<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Formula:C13H9ClF3N3OColor and Shape:SolidMolecular weight:315.68Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Formula:C27H17BrClNO5Color and Shape:SolidMolecular weight:550.78RJR-2403 oxalate
CAS:<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Formula:C14H18N2O4Purity:98%Color and Shape:SolidMolecular weight:278.308Bibn 140
CAS:<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Formula:C32H44N4O3Purity:98%Color and Shape:SolidMolecular weight:532.72AZD 0328
CAS:<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Formula:C13H16N2OColor and Shape:SolidMolecular weight:216.28Nelonicline citrate
CAS:<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Formula:C23H27N3O8SColor and Shape:SolidMolecular weight:505.54Bradanicline
CAS:<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Formula:C22H23N3O2Color and Shape:SolidMolecular weight:361.44Asoxime dichloride
CAS:<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Formula:C14H16Cl2N4O3Purity:99.86%Color and Shape:SolidMolecular weight:359.21Camylofine
CAS:<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Formula:C19H32N2O2·2HClPurity:98%Color and Shape:SolidMolecular weight:393.4(Rac)-VU 6008667
CAS:<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Formula:C24H17ClF2N2O2Purity:99.82%Color and Shape:SolidMolecular weight:438.85Pentolinium Tartrate
CAS:<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Formula:C15H32N2·2C4H5O6Purity:98%Color and Shape:SolidMolecular weight:538.6AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Formula:C27H38N6O2Purity:98%Color and Shape:SolidMolecular weight:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Formula:C11H16N2OPurity:98%Color and Shape:SolidMolecular weight:192.26CB-6673567
CAS:<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Formula:C19H14N4O3Color and Shape:SolidMolecular weight:346.34NGX-267
CAS:<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Formula:C10H18N2OSColor and Shape:SolidMolecular weight:214.33Dac 5945
CAS:<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Formula:C19H30ClN3OPurity:98%Color and Shape:SolidMolecular weight:351.91Hexocyclium metilsulfate
CAS:<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Formula:C21H36N2O5SPurity:98%Color and Shape:SolidMolecular weight:428.59GS 283
CAS:<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Formula:C17H17NO3Color and Shape:SolidMolecular weight:283.32(R)-VU 6008667
CAS:<p>(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).</p>Formula:C24H17ClF2N2O2Color and Shape:SolidMolecular weight:438.85Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Formula:C17H22BrNO5Color and Shape:White Crystals Or Crystalline PowderMolecular weight:400.27Btm 1042
CAS:<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Formula:C21H26ClN3OSColor and Shape:SolidMolecular weight:403.97Hyoscyamine hydrobromide
CAS:<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Formula:C17H24BrNO3Purity:98%Color and Shape:SolidMolecular weight:370.28Sazetidine A dihydrochloride
CAS:<p>α4β2 nicotinic acetylcholine receptor ligand</p>Formula:C15H21ClN2O2Purity:98%Color and Shape:SolidMolecular weight:296.79FR 121196
CAS:<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Formula:C12H16FN3O3SColor and Shape:SolidMolecular weight:301.34Prifuroline
CAS:<p>Prifuroline is an agent of antiarrhythmic.</p>Formula:C14H16N2OPurity:98%Color and Shape:SolidMolecular weight:228.29Epibatidine 2HCl
CAS:<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Formula:C11H15Cl3N2Purity:98%Color and Shape:SolidMolecular weight:281.61Flutropium Bromide
CAS:<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Formula:C24H29BrFNO3Purity:98%Color and Shape:SolidMolecular weight:478.39Vesamicol
CAS:<p>Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.</p>Formula:C17H25NOPurity:98%Color and Shape:SolidMolecular weight:259.39Siltenzepine
CAS:<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Formula:C19H20ClN3O4Purity:98%Color and Shape:SolidMolecular weight:389.83L 858051
CAS:<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Formula:C29H48N2O7Color and Shape:SolidMolecular weight:536.7DBO-83
CAS:<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Formula:C10H15Cl3N4Purity:98%Color and Shape:SolidMolecular weight:297.61ADX-10061
CAS:<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Formula:C16H21FN2O2Color and Shape:SolidMolecular weight:292.35Tebanicline tosylate
CAS:<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Formula:C16H19ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:370.85Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Formula:C20H28ClNPurity:98%Color and Shape:SolidMolecular weight:317.9YM-46303
CAS:<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Formula:C20H23ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:358.86CHF5407
CAS:<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Formula:C27H25BrF4N2O3SPurity:>99.99%Color and Shape:SolidMolecular weight:613.46YM-58790
CAS:<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Formula:C27H31N3O2Purity:98.59%Color and Shape:SoildMolecular weight:429.55Metixene hydrochloride
CAS:<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Formula:C20H24ClNSPurity:98%Color and Shape:SolidMolecular weight:345.93PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Formula:C22H20N4O3Purity:99.88%Color and Shape:SolidMolecular weight:388.42Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Formula:C20H30ClNO2Purity:99.79%Color and Shape:SolidMolecular weight:351.91PD-102807
CAS:<p>PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.</p>Formula:C23H24N2O4Purity:98.90%Color and Shape:SolidMolecular weight:392.45S 24795
CAS:<p>S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.</p>Formula:C14H13BrINOPurity:99.934%Color and Shape:SolidMolecular weight:418.07S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Formula:C41H71NO6Purity:99.69%Color and Shape:SolidMolecular weight:674.01Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Formula:C27H26F3N3O2Purity:99.83%Color and Shape:SolidMolecular weight:481.51UP202-56
CAS:<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Formula:C14H12N2O2Purity:99.59%Color and Shape:SolidMolecular weight:240.26Cimetropium Bromide
CAS:<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Formula:C21H28BrNO4Color and Shape:SolidMolecular weight:438.36GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37GAT107
CAS:<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Formula:C18H17BrN2O2SPurity:99.33%Color and Shape:SolidMolecular weight:405.31SCH 57790
CAS:<p>SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.</p>Formula:C25H31N3O2SPurity:99% - 99.12%Color and Shape:SolidMolecular weight:437.6
