AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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TC-T 6000
CAS:TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.Formula:C26H48N8O2Purity:98.14%Color and Shape:SolidMolecular weight:504.71AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Formula:C20H29FN2O2Color and Shape:SolidMolecular weight:348.45Asoxime dichloride
CAS:Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.Formula:C14H16Cl2N4O3Purity:99.75% - 99.86%Color and Shape:SolidMolecular weight:359.21Bradanicline
CAS:Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.Formula:C22H23N3O2Color and Shape:SolidMolecular weight:361.44Telenzepine
CAS:Telenzepine is a potent and selective M1 antimuscarinic.Formula:C19H22N4O2SPurity:98%Color and Shape:SolidMolecular weight:370.47Camylofine
CAS:Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.Formula:C19H32N2O2·2HClPurity:98%Color and Shape:SolidMolecular weight:393.4(Rac)-VU 6008667
CAS:(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.Formula:C24H17ClF2N2O2Purity:99.82%Color and Shape:SolidMolecular weight:438.85N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31(R,R)-Reboxetine mesylate
CAS:(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.Formula:C20H27NO6SColor and Shape:SolidMolecular weight:409.5Chlorisondamine chloride
CAS:Chlorisondamine chloride: a nicotinic antagonist, mainly for animal research, former antihypertensive.Formula:C14H20Cl6N2Color and Shape:SolidMolecular weight:429.03Darenzepine
CAS:Darenzepine is a muscarinic receptor inhibitor.Formula:C21H21N3O2Purity:99.87%Color and Shape:SolidMolecular weight:347.41Ref: TM-T10961
1mg203.00€5mg404.00€10mg567.00€25mg842.00€50mg1,125.00€100mg1,521.00€1mL*10mM (DMSO)447.00€Pirenzepine
CAS:Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4Phenglutarimid
CAS:Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H24N2O2Purity:98%Color and Shape:SolidMolecular weight:288.38A-85380 HCl
CAS:A-85380 is an agonist of nicotinic acetylcholine receptor.Formula:C9H14Cl2N2OColor and Shape:SolidMolecular weight:237.13Penehyclidine hydrochloride
CAS:Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.Formula:C20H30ClNO2Purity:99.79% - 99.91%Color and Shape:SolidMolecular weight:351.91Talsaclidine
CAS:Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.Formula:C10H15NOPurity:98%Color and Shape:SolidMolecular weight:165.23SCH 57790
CAS:SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.Formula:C25H31N3O2SPurity:99.12% - 99.69%Color and Shape:SolidMolecular weight:437.6RLH 033
CAS:RLH 033 is a selective ligand for the sigma 1 recognition site.Formula:C25H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:458.98BMS-902483
CAS:BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38J-104129 fumarate
CAS:J-104129 fumarate is a potent M3 muscarinic receptor antagonist.Formula:C28H40N2O6Color and Shape:SolidMolecular weight:500.63Mazaticol
CAS:Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.Formula:C21H27NO3S2Color and Shape:SolidMolecular weight:405.57(S)-VQW-765
(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.Formula:C19H22N2OColor and Shape:SolidMolecular weight:294.39SM-21 maleate
CAS:Increases release of acetylcholine,σ2 antagonistFormula:C22H28ClNO7Purity:98%Color and Shape:SolidMolecular weight:453.91GAT107
CAS:GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.Formula:C18H17BrN2O2SPurity:99.33%Color and Shape:SolidMolecular weight:405.31AFDX384
CAS:AFDX384 is potent M2/M4 selective antagonist.Formula:C28H42N6O5SColor and Shape:SolidMolecular weight:574.74DPNB-ABT594
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.Formula:C31H46ClN3O11Color and Shape:SolidMolecular weight:672.16TC 1698 dihydrochloride
CAS:nicotinic α7 receptor agonistFormula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3Parapenzolate bromide
CAS:Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.Formula:C21H26BrNO3Color and Shape:SolidMolecular weight:420.347Cycrimine
CAS:Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purity:98%Color and Shape:SolidMolecular weight:488.364-DAMP
CAS:4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formula:C21H26INO2Purity:98%Color and Shape:SolidMolecular weight:451.34Milameline hydrochloride
CAS:Milameline hydrochloride is a Muscarinic receptor agonist.Formula:C8H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:190.67Methapyrilene
CAS:Methapyrilene is a histamine H1 antagonist with sedative action.Formula:C14H19N3SColor and Shape:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:261.39Beperidium iodide
CAS:Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).Formula:C23H34IN3O3Color and Shape:SolidMolecular weight:527.44(±)-Muscarine chloride
CAS:(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71WIN 62,577
CAS:WIN 62,577 is a allosteric antagonist of mAChR.Formula:C29H31N3OPurity:98%Color and Shape:SolidMolecular weight:437.58Ambutonium bromide
CAS:Ambutonium bromide is an antagonist of acetylcholine.Formula:C20H27BrN2OPurity:98%Color and Shape:SolidMolecular weight:391.35Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formula:C22H34ClN3O3Purity:>99.99%Color and Shape:SolidMolecular weight:423.98Alvameline
CAS:Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.Formula:C9H15N5Purity:98%Color and Shape:SolidMolecular weight:193.25VU0455691
CAS:VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.Formula:C24H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:463.55Muscarine chloride
CAS:Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71Oxybutynin R-isomer HCl
CAS:Aroxybutynin, R-isomer of oxybutynin, is a muscarinic antagonist with antispasmodic effects on bladder muscle, weaker than atropine.Formula:C22H32ClNO3Color and Shape:SolidMolecular weight:393.95Procyclidine
CAS:Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Meseclazone
CAS:Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.Formula:C11H10ClNO3Purity:98%Color and Shape:SolidMolecular weight:239.65BPIPP
CAS:guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitorFormula:C22H16BrN3O3Purity:98%Color and Shape:SolidMolecular weight:450.28DREADD agonist 21 dihydrochloride
CAS:DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].Formula:C17H20Cl2N4Purity:98%Color and Shape:SolidMolecular weight:351.27Quifenadine
CAS:Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.Formula:C20H23NOPurity:98%Color and Shape:SolidMolecular weight:293.4Tarafenacin D-tartrate
CAS:Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C25H26F4N2O8Purity:99.86%Color and Shape:SolidMolecular weight:558.48PD-102807
CAS:PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.Formula:C23H24N2O4Purity:98.90%Color and Shape:SolidMolecular weight:392.45S 24795
CAS:S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.Formula:C14H13BrINOPurity:99.934%Color and Shape:SolidMolecular weight:418.07Ref: TM-T23286
5mg44.00€10mg66.00€25mg138.00€50mg215.00€100mg338.00€200mg480.00€1mL*10mM (DMSO)48.00€Bradanicline HCl
CAS:Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.Formula:C22H24ClN3O2Color and Shape:SolidMolecular weight:397.9Rivanicline oxalate
CAS:Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:252.27DAU 5884 hydrochloride
CAS:muscarinic M3 receptor antagonistFormula:C17H22ClN3O3Purity:98%Color and Shape:SolidMolecular weight:351.83Sulfoxaflor
CAS:Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.Formula:C10H10F3N3OSPurity:99.56% - 99.98%Color and Shape:SolidMolecular weight:277.27Ref: TM-T19940
1mg100.00€5mg275.00€10mg384.00€25mg572.00€50mg780.00€100mg1,018.00€250mg2,080.00€1mL*10mM (DMSO)245.00€AT-1001
CAS:AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.Formula:C15H21BrN2Color and Shape:SolidMolecular weight:309.24Tarafenacin
CAS:Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C21H20F4N2O2Purity:98%Color and Shape:SolidMolecular weight:408.39Vinconate
CAS:Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.Formula:C18H20N2O2Purity:98%Color and Shape:SolidMolecular weight:296.36SR 16584
CAS:α3β4 nAChR antagonistFormula:C17H22N2OPurity:99.84%Color and Shape:SolidMolecular weight:270.37Alvameline maleate
CAS:Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.Formula:C13H19N5O4Color and Shape:SolidMolecular weight:309.32Sch412348
CAS:Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.Formula:C22H21F2N9OPurity:98%Color and Shape:SolidMolecular weight:465.46J 104129 fumarate
CAS:M3 muscarinic receptor antagonistFormula:C24H36N2O2Purity:98%Color and Shape:SolidMolecular weight:384.55Nelonicline
CAS:Nelonicline is a selective agonist of neuronal nicotinic receptors.Formula:C17H19N3OSPurity:98%Color and Shape:SolidMolecular weight:313.42BTM-1086
CAS:BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Formula:C21H25N3OSPurity:98%Color and Shape:SolidMolecular weight:367.51RJR 2429 dihydrochloride
CAS:nAChR agonist that displays selectivity for α4β2Formula:C12H18Cl2N2Purity:98%Color and Shape:SolidMolecular weight:261.19VMY-2-95
CAS:VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.Formula:C17H16N2OColor and Shape:SolidMolecular weight:264.32S16961
CAS:S16961 (S169611) is an agonist of nicotinic receptor.Formula:C41H71NO6Purity:99.69%Color and Shape:SolidMolecular weight:674.01Arecaidine propargyl ester tosylate
CAS:Arecaidine propargyl ester tosylate is a muscarinic receptor agonist.Formula:C17H21NO5SPurity:98%Color and Shape:SolidMolecular weight:351.42CP-601927
CAS:CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Formula:C27H26F3N3O2Purity:99.83%Color and Shape:SolidMolecular weight:481.51SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFormula:C13H20ClNOSPurity:99.56% - 99.73%Color and Shape:SolidMolecular weight:273.82CP-601932
CAS:CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23ML375
CAS:ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).Formula:C23H15ClF2N2O2Color and Shape:SolidMolecular weight:424.83Rapacuronium bromide
CAS:Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.Formula:C37H61BrN2O4Purity:98%Color and Shape:SolidMolecular weight:677.8Eucatropine
CAS:Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.Formula:C17H25NO3Color and Shape:SolidMolecular weight:291.39UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69CB-7921220
CAS:CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.Formula:C14H12N2O2Purity:99.59%Color and Shape:SolidMolecular weight:240.26Rivanicline
CAS:Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.Formula:C10H14N2Purity:98%Color and Shape:SolidMolecular weight:162.23Thiochrome
CAS:Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.Formula:C12H14N4OSPurity:98%Color and Shape:SolidMolecular weight:262.33Cimetropium Bromide
CAS:Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.Formula:C21H28BrNO4Color and Shape:SolidMolecular weight:438.36VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Formula:C24H17ClF2N2O2Purity:98%Color and Shape:SolidMolecular weight:438.85GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37VU0090157
CAS:VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.Formula:C19H21N3O7Purity:98%Color and Shape:SolidMolecular weight:403.39Bibn 99
CAS:Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.Formula:C31H42ClN5O3Color and Shape:SolidMolecular weight:568.15Rispenzepine
CAS:Rispenzepine, a novel mAChRs M1/M3 antagonist, treats immune, infections, and respiratory issues.Formula:C19H20N4O2Purity:98%Color and Shape:SolidMolecular weight:336.39Revatropate
CAS:Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.Formula:C19H27NO4SColor and Shape:SolidMolecular weight:365.49Sofiniclin
CAS:Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).Formula:C10H11Cl2N3Purity:98%Color and Shape:SolidMolecular weight:244.12Milameline
CAS:Milameline is a muscarinic receptor agonist that improves cognition.Formula:C8H14N2OColor and Shape:SolidMolecular weight:154.21S-(+)-Mecamylamine hydrochloride
CAS:Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.Formula:C11H22ClNColor and Shape:SolidMolecular weight:203.75T761-0184
CAS:T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].Formula:C16H20FN3OColor and Shape:SolidMolecular weight:289.35ML169
CAS:ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).Formula:C21H17BrFN3O4SPurity:98%Color and Shape:SolidMolecular weight:506.34L 858051
CAS:L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.Formula:C29H48N2O7Color and Shape:SolidMolecular weight:536.7M1 ligand 1
CAS:Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.Formula:C20H21NO2Color and Shape:SolidMolecular weight:307.39DA 4626
CAS:DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.Formula:C14H18N4Purity:98%Color and Shape:SolidMolecular weight:242.32DBO-83
CAS:DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.Formula:C10H15Cl3N4Purity:98%Color and Shape:SolidMolecular weight:297.61ADX-10061
CAS:ADX-10061 is a dopamine D1 receptor antagonist.Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37JN403
CAS:JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.Formula:C16H21FN2O2Color and Shape:SolidMolecular weight:292.35Nuvenzepine
CAS:Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.Formula:C19H20N4O2Purity:98%Color and Shape:SolidMolecular weight:336.39Methacholine bromide
CAS:Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.Formula:C8H18BrNO2Color and Shape:SolidMolecular weight:240.141Terodiline
CAS:Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.Formula:C20H27NPurity:98.20% - 99.59%Color and Shape:SolidMolecular weight:281.44Nelonicline citrate
CAS:Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.Formula:C23H27N3O8SColor and Shape:SolidMolecular weight:505.54
