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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • Br-PBTC
    Targetmol
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    Br-PBTC

    CAS:
    <p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>
    Formula:C14H15BrN2OS
    Color and Shape:Solid
    Molecular weight:339.25

    Ref: TM-T39286

  • β2AR/M-receptor agonist-1
    Targetmol
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    β2AR/M-receptor agonist-1

    CAS:
    <p>β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and</p>
    Formula:C43H56BrN3O7
    Color and Shape:Solid
    Molecular weight:806.82

    Ref: TM-T74708

  • Dexetimide
    Targetmol
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    Dexetimide

    CAS:
    <p>Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.</p>
    Formula:C23H26N2O2
    Color and Shape:Solid
    Molecular weight:362.46

    Ref: TM-T15104

  • Metixene hydrochloride hydrate
    Targetmol
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    Metixene hydrochloride hydrate

    CAS:
    <p>Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.</p>
    Formula:C20H26ClNOS
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:363.95

    Ref: TM-TQ0304

  • Fipexide hydrochloride
    Targetmol
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    Fipexide hydrochloride

    CAS:
    <p>Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.</p>
    Formula:C20H22Cl2N2O4
    Color and Shape:Solid
    Molecular weight:425.31

    Ref: TM-T22332

  • NKH477
    Targetmol
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    NKH477

    CAS:
    <p>NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.</p>
    Formula:C27H44ClNO8
    Purity:98% - 98%
    Color and Shape:Solid
    Molecular weight:546.09

    Ref: TM-T16332

  • Tolterodine
    Targetmol
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    Tolterodine

    CAS:
    <p>Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.</p>
    Formula:C22H31NO
    Purity:99.71%
    Color and Shape:White Like Or Light Brown Crystalline Powder
    Molecular weight:325.49

    Ref: TM-T23229

  • YM-58790 hydrochloride
    Targetmol
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    YM-58790 hydrochloride

    CAS:
    <p>YM-58790 is a potent M3 muscarinic receptor antagonist(Ki of 15 nM).</p>
    Formula:C27H32ClN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:466.02

    Ref: TM-T13372

  • Palmatine hydroxide
    Targetmol
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    Palmatine hydroxide

    CAS:
    <p>Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.</p>
    Formula:C21H23NO5
    Color and Shape:Solid
    Molecular weight:369.41

    Ref: TM-T72508

  • Cevimeline
    Targetmol
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    Cevimeline

    CAS:
    <p>Cevimeline: muscarinic agonist, treats dry mouth &amp; Sjögren's, boosts saliva post-cancer radiotherapy.</p>
    Formula:C10H17NOS
    Color and Shape:Off-White Solid
    Molecular weight:199.31

    Ref: TM-T21119

  • Pirmenol hydrochloride
    Targetmol
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    Pirmenol hydrochloride

    CAS:
    <p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>
    Formula:C22H31ClN2O
    Color and Shape:Solid
    Molecular weight:374.95

    Ref: TM-T61529

  • Varenicline Hydrochloride
    Targetmol
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    Varenicline Hydrochloride

    CAS:
    <p>Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).</p>
    Formula:C13H14ClN3
    Purity:99.854%
    Color and Shape:Solid
    Molecular weight:247.72

    Ref: TM-T23502

  • Cevimeline hydrochloride
    Targetmol
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    Cevimeline hydrochloride

    CAS:
    <p>Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.</p>
    Formula:C10H18ClOS
    Color and Shape:Solid
    Molecular weight:235.77

    Ref: TM-T20131

  • Glycerophosphoinositol choline
    Targetmol
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    Glycerophosphoinositol choline

    CAS:
    <p>Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.</p>
    Formula:C14H32NO12P
    Color and Shape:Solid
    Molecular weight:437.38

    Ref: TM-T31951

  • Ispronicline
    Targetmol
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    Ispronicline

    CAS:
    <p>Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive</p>
    Formula:C14H22N2O
    Purity:97.70% - 99.16%
    Color and Shape:Solid
    Molecular weight:234.34

    Ref: TM-T27636

  • Sabcomeline hydrochloride
    Targetmol
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    Sabcomeline hydrochloride

    CAS:
    <p>Sabcomeline is a selective M1 receptor partial agonist.</p>
    Formula:C10H16ClN3O
    Color and Shape:Solid
    Molecular weight:229.71

    Ref: TM-T28654

  • (±)-Darifenacin
    Targetmol
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    (±)-Darifenacin

    CAS:
    <p>(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.</p>
    Formula:C28H30N2O2
    Color and Shape:Solid
    Molecular weight:426.55

    Ref: TM-T12680

  • VU0467485
    Targetmol
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    VU0467485

    CAS:
    <p>VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.</p>
    Formula:C17H17FN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.41

    Ref: TM-T17245

  • Clorprenaline
    Targetmol
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    Clorprenaline

    CAS:
    <p>Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.</p>
    Formula:C11H16ClNO
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:213.7

    Ref: TM-T60261

  • ABT-107
    Targetmol
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    ABT-107

    CAS:
    <p>ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.</p>
    Formula:C19H20N4O
    Color and Shape:Solid
    Molecular weight:320.396

    Ref: TM-T40951