AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 645 products of "AChR"
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VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7VU0152100
CAS:VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).Formula:C18H19N3O2SPurity:99.56%Color and Shape:SolidMolecular weight:341.43Ref: TM-T17238
2mg39.00€5mg58.00€10mg92.00€25mg195.00€50mg325.00€100mg522.00€200mg743.00€1mL*10mM (DMSO)64.00€Nitrobenzylthioinosine
CAS:Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.Formula:C17H17N5O6SPurity:99.69% - 99.74%Color and Shape:Off-White SolidMolecular weight:419.41Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purity:99.35%Color and Shape:SolidMolecular weight:218.68Pempidine HCl
CAS:Pempidine HCl, a nicotinic antagonist and former hypertension treatment, now mainly serves as a lab tool.Formula:C10H22ClNColor and Shape:SolidMolecular weight:191.74Dinotefuran
CAS:Dinotefuran (MTI-446), a neonicotinoid insecticide, targets pests by blocking their nervous system.Formula:C7H14N4O3Purity:99.89%Color and Shape:White Crystalline PowderMolecular weight:202.21VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Formula:C17H15F3N4O3S2Purity:99.51% - 99.53%Color and Shape:SolidMolecular weight:444.45Ref: TM-T17244
1mg47.00€2mg63.00€5mg92.00€10mg126.00€25mg236.00€50mg400.00€100mg695.00€200mg945.00€1mL*10mM (DMSO)101.00€NS9283
CAS:NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.
Formula:C14H8N4OPurity:99.12%Color and Shape:SolidMolecular weight:248.24ML380
CAS:ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Ref: TM-T28069
2mg47.00€5mg71.00€10mg113.00€25mg178.00€50mg334.00€100mg500.00€500mg1,099.00€1mL*10mM (DMSO)78.00€BNC210
CAS:BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.Formula:C17H23N3O3Purity:97.05% - >99.99%Color and Shape:SolidMolecular weight:317.38Isopropamide Iodide
CAS:Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.
Formula:C23H33IN2OPurity:99.67%Color and Shape:SolidMolecular weight:480.43Mc-Val-Ala-PAB
CAS:Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).Formula:C25H34N4O6Purity:98.34% - 99.24%Color and Shape:SolidMolecular weight:486.56Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Formula:C11H15ClN4O2Purity:99.03%Color and Shape:Light-Yellow CrystalMolecular weight:270.72Mecamylamine hydrochloride
CAS:Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.Formula:C11H22ClNPurity:99.76% - >99.99%Color and Shape:White SolidMolecular weight:203.75Solifenacin hydrochloride
CAS:Solifenacin Hcl is a muscarinic receptor antagonist.Formula:C23H27ClN2O2Purity:98%Color and Shape:SolidMolecular weight:398.93Encenicline
CAS:Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.Formula:C16H17ClN2OSPurity:99.20%Color and Shape:SolidMolecular weight:320.84Ref: TM-T7193
1mg70.00€5mg133.00€10mg207.00€25mg349.00€50mg495.00€100mg675.00€200mg888.00€1mL*10mM (DMSO)144.00€Mecamylamine
CAS:Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.Formula:C11H21NColor and Shape:SolidMolecular weight:167.29Oxyphencyclimine Hydrochloride
CAS:Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.Formula:C20H29ClN2O3Purity:99.55%Color and Shape:SolidMolecular weight:380.91Propiverine
CAS:Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.Formula:C23H29NO3Color and Shape:SolidMolecular weight:367.48NS 1738
CAS:NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)Formula:C14H9Cl2F3N2O2Purity:99.11%Color and Shape:SolidMolecular weight:365.13
