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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • TQS
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    TQS

    CAS:
    <p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>
    Formula:C22H20N2O2S
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:376.47

    Ref: TM-T23469

  • Sofpironium bromide
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    Sofpironium bromide

    CAS:
    <p>Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.</p>
    Formula:C22H32BrNO5
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:470.4

    Ref: TM-T28827

  • Dinotefuran
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    Dinotefuran

    CAS:
    <p>Dinotefuran (MTI-446), a neonicotinoid insecticide, targets pests by blocking their nervous system.</p>
    Formula:C7H14N4O3
    Purity:99.89%
    Color and Shape:White Crystalline Powder
    Molecular weight:202.21

    Ref: TM-T7124

  • MC-Val-Cit-PAB
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    MC-Val-Cit-PAB

    CAS:
    <p>MC-Val-Cit-PAB: cathepsin-cleavable ADC linker used in FDA-approved brentuximab vedotin.</p>
    Formula:C28H40N6O7
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:572.65

    Ref: TM-T5149

  • Revefenacin
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    Revefenacin

    CAS:
    <p>Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.</p>
    Formula:C35H43N5O4
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:597.75

    Ref: TM-T7392

  • Pempidine
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    Pempidine

    CAS:
    <p>Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.</p>
    Formula:C10H21N
    Purity:98.18% - 99.28%
    Color and Shape:Colorless - Light Yellow Clear Liquid
    Molecular weight:155.28

    Ref: TM-T0296

  • Dronedarone
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    Dronedarone

    CAS:
    <p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>
    Formula:C31H44N2O5S
    Purity:98.85% - 99.58%
    Color and Shape:Solid
    Molecular weight:556.76

    Ref: TM-T7056

  • Nitrocaramiphen hydrochloride
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    Nitrocaramiphen hydrochloride

    CAS:
    <p>Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.</p>
    Formula:C18H27ClN2O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:370.87

    Ref: TM-T23071

  • Anisotropine Methylbromide
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    Anisotropine Methylbromide

    CAS:
    <p>Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.</p>
    Formula:C17H32BrNO2
    Purity:99.73%
    Color and Shape:Crystals From Acetone Solid
    Molecular weight:362.35

    Ref: TM-T4981

  • Solifenacin
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    Solifenacin

    CAS:
    Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,
    Formula:C23H26N2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:362.46

    Ref: TM-T8147

  • Piperidolate
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    Piperidolate

    CAS:
    <p>Piperidolate inhibits intestinal cramp induced by acetylcholine</p>
    Formula:C21H25NO2
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:323.43

    Ref: TM-T7405

  • PNU-282987 S enantiomer free base
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    PNU-282987 S enantiomer free base

    CAS:
    <p>PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).</p>
    Formula:C14H17ClN2O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:264.75

    Ref: TM-T7695

  • VU 0238429
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    VU 0238429

    CAS:
    <p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>
    Formula:C17H12F3NO4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:351.28

    Ref: TM-T8007

  • VU0238441
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    VU0238441

    CAS:
    <p>VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.</p>
    Formula:C16H9ClF3NO2
    Purity:100%
    Color and Shape:Solid
    Molecular weight:339.7

    Ref: TM-T8219

  • Glycopyrrolate
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    Glycopyrrolate

    CAS:
    <p>Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.</p>
    Formula:C19H28BrNO3
    Purity:99.41% - 99.64%
    Color and Shape:Solid
    Molecular weight:398.33

    Ref: TM-T2387

  • PHA 543613 hydrochloride
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    PHA 543613 hydrochloride

    CAS:
    <p>PHA-543613 hydrochloride, a potent α7 nicotinic receptor agonist, may treat schizophrenia-related cognitive deficits.</p>
    Formula:C15H18ClN3O2
    Color and Shape:Solid
    Molecular weight:307.78

    Ref: TM-T70420

  • Nitenpyram
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    Nitenpyram

    CAS:
    <p>Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.</p>
    Formula:C11H15ClN4O2
    Purity:99.03%
    Color and Shape:Light-Yellow Crystal
    Molecular weight:270.72

    Ref: TM-T6607

  • Harman hydrochloride
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    Harman hydrochloride

    CAS:
    <p>Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.</p>
    Formula:C12H11ClN2
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:218.68

    Ref: TM-T3158L

  • CCMI
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    CCMI

    CAS:
    <p>CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.</p>
    Formula:C19H15Cl2N3O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:388.25

    Ref: TM-T7422

  • W-84 dibromide
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    W-84 dibromide

    CAS:
    <p>W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.</p>
    Formula:C32H44Br2N4O4
    Purity:95.56%
    Color and Shape:Solid
    Molecular weight:708.52

    Ref: TM-T23524