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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • Muscarine tosylate
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    Muscarine tosylate

    CAS:
    <p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>
    Formula:C16H27NO5S
    Color and Shape:Solid
    Molecular weight:345.45

    Ref: TM-T84726

  • AR420626
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    AR420626

    CAS:
    <p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>
    Formula:C21H18Cl2N2O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:417.29

    Ref: TM-T26647

  • mAChR antagonist 1
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    mAChR antagonist 1

    CAS:
    <p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>
    Formula:C19H22N2O2
    Color and Shape:Solid
    Molecular weight:310.39

    Ref: TM-T81888

  • Homatropine hydrochloride
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    Homatropine hydrochloride

    CAS:
    <p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>
    Formula:C16H22ClNO3
    Color and Shape:Solid
    Molecular weight:311.8

    Ref: TM-T80637

  • 3-Bromocytisine
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    3-Bromocytisine

    CAS:
    <p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>
    Formula:C11H13BrN2O
    Purity:99.974%
    Color and Shape:Solid
    Molecular weight:269.14

    Ref: TM-T10108

  • UFP-512
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    UFP-512

    CAS:
    <p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>
    Formula:C31H33N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:555.62

    Ref: TM-T29046

  • A-424274
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    A-424274

    CAS:
    <p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>
    Formula:C14H15N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:225.29

    Ref: TM-T23594

  • L 687306
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    L 687306

    CAS:
    <p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>
    Formula:C11H15N3O
    Color and Shape:Solid
    Molecular weight:205.26

    Ref: TM-T24333

  • BMS-933043
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    BMS-933043

    CAS:
    <p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) &amp; human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>
    Formula:C16H19N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.37

    Ref: TM-T26865

  • Tematropium
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    Tematropium

    CAS:
    <p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>
    Formula:C21H31NO8S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:457.54

    Ref: TM-T10732

  • (-)-Cevimeline hydrochloride hemihydrate
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    (-)-Cevimeline hydrochloride hemihydrate

    <p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>
    Formula:C10H19ClNO1·5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:244.78

    Ref: TM-T13421

  • Lu 26-046
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    Lu 26-046

    CAS:
    <p>Lu 26-046 is a muscarinic receptor agonist.</p>
    Formula:C10H12N2OS
    Color and Shape:Solid
    Molecular weight:208.28

    Ref: TM-T70651

  • CymitQuimica logo
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    (+)-Sparteine sulfate pentahydrate

    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Formula:C15H38N2O9S
    Color and Shape:Solid
    Molecular weight:422.54

    Ref: TM-T62265

  • (+)-Cevimeline hydrochloride hemihydrate
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    (+)-Cevimeline hydrochloride hemihydrate

    <p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>
    Formula:C10H19ClNO1·5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:244.78

    Ref: TM-T13460

  • Dihydro-β-erythroidine hydrobromide
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    Dihydro-β-erythroidine hydrobromide

    CAS:
    <p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>
    Formula:C16H22BrNO3
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:356.26

    Ref: TM-T11041

  • WIN 62577
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    WIN 62577

    CAS:
    <p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>
    Formula:C29H31N3O
    Color and Shape:Solid
    Molecular weight:437.576

    Ref: TM-T206261

  • Metoquizine
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    Metoquizine

    CAS:
    <p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>
    Formula:C22H27N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.48

    Ref: TM-T25805

  • (S)-Albuterol
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    (S)-Albuterol

    CAS:
    <p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>
    Formula:C13H21NO3
    Color and Shape:Solid
    Molecular weight:239.311

    Ref: TM-T206288

  • CymitQuimica logo
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    nAChR antagonist 1

    CAS:
    <p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>
    Formula:C19H22N4O2
    Color and Shape:Solid
    Molecular weight:338.4

    Ref: TM-T61064

  • 1,9-Dideoxyforskolin
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    1,9-Dideoxyforskolin

    CAS:
    <p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>
    Formula:C22H34O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.5

    Ref: TM-T22467