AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Formula:C6H15ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:182.65TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
Formula:C24H24FN3O3Purity:98.02%Color and Shape:SolidMolecular weight:421.46Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Formula:C10H11ClN4Purity:99.66%Color and Shape:White PowderMolecular weight:222.67Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Formula:C20H25NO2·HClPurity:97.76% - 99.53%Color and Shape:White Or Almost White PowderMolecular weight:347.88Rocuronium bromide
CAS:Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker, which is used to provide skeletal muscle relaxation.Formula:C32H53BrN2O4Purity:99.77% - >99.99%Color and Shape:White Or Off-White PowderMolecular weight:609.68Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Formula:C27H42ClNO2Purity:99.91%Color and Shape:White To Off-White Solid Solid Particulate/PowderMolecular weight:448.09Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Formula:C19H36ClNO2Purity:99.81%Color and Shape:SolidMolecular weight:345.95Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Formula:C35H60Br2N2O4Purity:99.86%Color and Shape:solidMolecular weight:732.67VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Formula:C22H14F3NO3Purity:99.86%Color and Shape:SolidMolecular weight:397.35Ref: TM-T13325
2mg35.00€5mg55.00€10mg78.00€25mg130.00€50mg212.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)62.00€Fesoterodine fumarate
CAS:Fesoterodine fumarate (Toviaz) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.Formula:C26H37NO3·C4H4O4Purity:99.16%Color and Shape:White SolidMolecular weight:527.65Ref: TM-T1475
2mg34.00€5mg50.00€10mg71.00€25mg100.00€50mg137.00€100mg205.00€500mg396.00€1mL*10mM (DMSO)54.00€Carbetapentane citrate
CAS:Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.Formula:C20H31NO3·C6H8O7Purity:99.46%Color and Shape:White To Off-White SolidMolecular weight:525.59N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.19α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFormula:C79H125N27O25S4Purity:98%Color and Shape:SolidMolecular weight:1981.3GeX-2
CAS:GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purity:98%Color and Shape:SolidMolecular weight:2093.37rac-Desethyl Oxybutynin (hydrochloride)
CAS:rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89Navafenterol
CAS:AZD-8871, a potential COPD and asthma treatment, may work well with ICS.Formula:C38H42N6O6S2Color and Shape:SolidMolecular weight:742.91TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Formula:C16H16ClN5Purity:99.85% - 99.89%Color and Shape:SoildMolecular weight:313.78Ref: TM-T64355
1mg39.00€5mg157.00€10mg224.00€25mg409.00€50mg615.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)167.00€
