AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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Oxotremorine
CAS:Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.Formula:C12H18N2OColor and Shape:SolidMolecular weight:206.28VU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Formula:C23H27F3N4OColor and Shape:SolidMolecular weight:432.491Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Formula:C21H32BrNO2Color and Shape:SolidMolecular weight:410.39R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Formula:C10H12N2OColor and Shape:SolidMolecular weight:176.22Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.63% - 99.96%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg120.00€2mg170.00€5mg289.00€10mg467.00€25mg835.00€50mg1,134.00€100mg1,504.00€1mL*10mM (DMSO)319.00€α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purity:98%Color and Shape:SolidMolecular weight:2093.37Biperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Formula:C21H30ClNOPurity:98%Color and Shape:SolidMolecular weight:347.92TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Formula:C202H325N61O54SPurity:98%Color and Shape:SolidMolecular weight:4504.2Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Formula:C10H15ClN2OColor and Shape:SolidMolecular weight:214.69N,N-Dicyclohexylcarbodiimide
CAS:N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent used in the synthesis of active ester-containing reagents.Formula:C13H22N2Purity:98.28% - 99.73%Color and Shape:SolidMolecular weight:206.33DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Color and Shape:Odour SolidSmall Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Formula:C52H80N14O11S2Purity:98%Color and Shape:SolidMolecular weight:1141.41ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Formula:C36H58N2O5SColor and Shape:SolidMolecular weight:630.92Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFormula:C9H16ClNO2Purity:98%Color and Shape:SolidMolecular weight:205.68LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Color and Shape:SolidMolecular weight:1985.31LAS190792
CAS:LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.Formula:C39H43ClN4O9S2Color and Shape:SolidMolecular weight:811.36(S)-Dinotefuran
CAS:(S)-Dinotefuran, a neonicotinoid, more toxic to bees than its R-isomer, targets α8 nAChR.Formula:C7H14N4O3Color and Shape:SolidMolecular weight:202.21(Rac)-5-Carboxy tolterodine
CAS:(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47Thiothixene
CAS:Thiothixene has a wide range of applications in life science related research.Formula:C23H29N3O2S2Color and Shape:SolidMolecular weight:443.62nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66
