AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 645 products of "AChR"
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S16961
CAS:S16961 (S169611) is an agonist of nicotinic receptor.Formula:C41H71NO6Purity:99.69%Color and Shape:SolidMolecular weight:674.01Tebanicline tosylate
CAS:Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.Formula:C16H19ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:370.85Neramexane Mesylate
CAS:Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.Formula:C12H27NO3SPurity:98%Color and Shape:SolidMolecular weight:265.41Alvameline
CAS:Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.Formula:C9H15N5Purity:98%Color and Shape:SolidMolecular weight:193.25ML381
CAS:ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.Formula:C21H21N3O4Purity:99.87%Color and Shape:SolidMolecular weight:379.41Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Formula:C27H26F3N3O2Purity:99.83%Color and Shape:SolidMolecular weight:481.51Muscarine chloride
CAS:Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71Biricodar dicitrate
CAS:Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.Formula:C46H57N3O21Purity:97.78% - 99.78%Color and Shape:SolidMolecular weight:987.95Terodiline hydrochloride
CAS:Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),
Formula:C20H28ClNPurity:98%Color and Shape:SolidMolecular weight:317.9mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purity:98%Color and Shape:SolidMolecular weight:488.36YM-46303
CAS:YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia inFormula:C20H23ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:358.86CHF5407
CAS:CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFormula:C27H25BrF4N2O3SPurity:99.54% - >99.99%Color and Shape:SolidMolecular weight:613.464-DAMP
CAS:4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formula:C21H26INO2Purity:98%Color and Shape:SolidMolecular weight:451.34Tarafenacin D-tartrate
CAS:Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C25H26F4N2O8Purity:99.86%Color and Shape:SolidMolecular weight:558.48KL8604166
CAS:KL8604166 (UCB-11056) is a potential puzzle compound.UCB-11056 amplifies the formation of inducible cyclic AMP in rat brain tissue.Formula:C12H21N5O2Purity:99.21%Color and Shape:SolidMolecular weight:267.33Ref: TM-T29038
1mg264.00€5mg650.00€10mg888.00€25mg1,369.00€50mg1,783.00€100mg2,250.00€1mL*10mM (DMSO)590.00€PF-06767832
CAS:PF-06767832: selective M1 PAM (EC50=60 nM), no M2-M5 activity, good CNS penetration, but has GI and cardiovascular risks.Formula:C22H23N3O3SColor and Shape:SolidMolecular weight:409.5Hadacidin
CAS:Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H5NO4Color and Shape:SolidMolecular weight:119.08ML169
CAS:ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).Formula:C21H17BrFN3O4SPurity:98%Color and Shape:SolidMolecular weight:506.34Glucagon Receptor Antagonist I
CAS:Glucagon antagonist I blocks the GCGR (IC50=181 nM), stops glucagon-induced glycogenolysis, and lowers glucose in glucagon-treated humanized mice.Formula:C20H30N2OSColor and Shape:SolidMolecular weight:346.53Sulfoxaflor
CAS:Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.Formula:C10H10F3N3OSPurity:99.56% - 99.98%Color and Shape:SolidMolecular weight:277.27Ref: TM-T19940
1mg100.00€5mg275.00€10mg384.00€25mg572.00€50mg780.00€100mg1,018.00€250mg2,080.00€1mL*10mM (DMSO)245.00€RJR-2429
CAS:RJR-2429 is a potent AChR agonist.Formula:C12H16N2Color and Shape:SolidMolecular weight:188.27Meseclazone
CAS:Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.Formula:C11H10ClNO3Purity:98%Color and Shape:SolidMolecular weight:239.65CC4
CAS:Selective α6β2/α4β2 partial agonist; Ki: 12/26nM (rat); poor α3β4/α7 affinity; stimulates dopamine release; reduces nicotine self-admin in rats.Formula:C24H30N4O2Color and Shape:SolidMolecular weight:406.52Hadacidin sodium
CAS:Hadacidin sodium is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H4NNaO4Color and Shape:SolidMolecular weight:141.06Dexetimide HCl
CAS:Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.Formula:C23H27ClN2O2Color and Shape:SolidMolecular weight:398.93(E/Z)-VU0029767
CAS:VU0029767 enhances M1 muscarinic receptor function, increasing acetylcholine potency and efficacy.Formula:C21H21N3O3Color and Shape:SolidMolecular weight:363.41Octamylamine sulfamate
CAS:Octamylamine sulfamate is a P450 inhibitor.Formula:C13H32N2O3SColor and Shape:SolidMolecular weight:296.47Zamifenacin
CAS:Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.Formula:C27H29NO3Purity:98%Color and Shape:SolidMolecular weight:415.52Quifenadine
CAS:Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.Formula:C20H23NOPurity:98%Color and Shape:SolidMolecular weight:293.4DAU 5884 hydrochloride
CAS:muscarinic M3 receptor antagonistFormula:C17H22ClN3O3Purity:98%Color and Shape:SolidMolecular weight:351.83Metanicotine
CAS:Metanicotine is a selective nicotinic agonist with antinociceptive properties.Formula:C10H14N2Color and Shape:SolidMolecular weight:162.23Caramiphen hydrochloride
CAS:Caramiphen hydrochloride: antimuscarinic, anticholinergic, NMDA receptor antagonist salt.Formula:C18H28ClNO2Color and Shape:SolidMolecular weight:325.88BNC375
CAS:BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).Formula:C19H23ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:394.92UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69TC-1698 dihydrochloride
CAS:TC-1698 dihydrochloride: selective α7 nicotinic agonist, with some β-receptor activity; neuroprotectant.Formula:C13H20Cl2N2Color and Shape:SolidMolecular weight:275.22Octamylamine hydrochloride
CAS:Octamylamine hydrochloride is a P450 inhibitor.Formula:C13H30ClNColor and Shape:SolidMolecular weight:235.84Neopterin, L-erythro-
CAS:Neopterin, L-erythro- can be used as a cholinergic receptor.Formula:C9H11N5O4Color and Shape:SolidMolecular weight:253.21Methacholine iodide
CAS:Methacholine iodide is a muscarinic acetylcholine receptor agonist.Formula:C8H18INO2Color and Shape:SolidMolecular weight:287.14CB-7921220
CAS:CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.Formula:C14H12N2O2Purity:99.59%Color and Shape:SolidMolecular weight:240.26(R,R)-Reboxetine mesylate
CAS:(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.Formula:C20H27NO6SColor and Shape:SolidMolecular weight:409.5VU0090157
CAS:VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.Formula:C19H21N3O7Purity:98%Color and Shape:SolidMolecular weight:403.39AQ-RA 721
CAS:AQ-RA 721 is a selective muscarinic antagonist with high affinity for M1- and M3-receptors. AQ-RA 721 may be used as a bronchodilator.Formula:C22H23N3O2Color and Shape:SolidMolecular weight:361.44Nelonicline
CAS:Nelonicline is a selective agonist of neuronal nicotinic receptors.Formula:C17H19N3OSPurity:98%Color and Shape:SolidMolecular weight:313.42AZD-9164 bromide
CAS:AMG-221, a selective 11β-HSD1 inhibitor, suppresses enzyme activity, lowers glucose/insulin, and reduces weight in obese mice.Formula:C29H38BrFN2O2Color and Shape:SolidMolecular weight:545.53UH-AH 37
CAS:UH-AH 37 is a antagonist of human muscarinic acetylcholine receptor.Formula:C21H23Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:420.33DAU 5884 HCl
CAS:DAU 5884 HCl is an M3 receptor antagonistFormula:C17H21N3O3Color and Shape:SolidMolecular weight:315.37Ethybenztropine HBr
CAS:Ethybenztropine HBr is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.Formula:C22H28BrNOColor and Shape:SolidMolecular weight:402.37Atropine Oxide Hydrochloride
CAS:Atropine Oxide, a derivative of anticholinergic Atropine, treats poisonings, slow heart rate, and reduces saliva during surgery.Formula:C17H24ClNO4Color and Shape:SolidMolecular weight:341.83YM-58790
CAS:YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.Formula:C27H31N3O2Purity:99.87%Color and Shape:SoildMolecular weight:429.55M1 ligand 1
CAS:Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.Formula:C20H21NO2Color and Shape:SolidMolecular weight:307.39
