AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 645 products of "AChR"
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Metixene hydrochloride
CAS:Metixene hydrochloride is an anticholinergic antiparkinsonian agent.Formula:C20H24ClNSPurity:98%Color and Shape:SolidMolecular weight:345.93Benzatropine
CAS:Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.Formula:C21H25NOPurity:98%Color and Shape:SolidMolecular weight:307.43Cimetropium Bromide
CAS:Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.Formula:C21H28BrNO4Color and Shape:SolidMolecular weight:438.36UB 165 fumarate
CAS:UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.Formula:C17H19ClN2O4Purity:99.72%Color and Shape:SolidMolecular weight:350.8Ethybenztropine HCl
CAS:Ethybenztropine HCl is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.Formula:C22H28ClNOColor and Shape:SolidMolecular weight:357.92Esoxybutynin Chloride
CAS:(S)-oxybutynin, with antimuscarinic effects, is being developed for urinary incontinence.Formula:C22H32ClNO3Color and Shape:SolidMolecular weight:393.95S-(+)-Mecamylamine hydrochloride
CAS:Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.Formula:C11H22ClNColor and Shape:SolidMolecular weight:203.75BTM-1086
CAS:BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Formula:C21H25N3OSPurity:98%Color and Shape:SolidMolecular weight:367.51Muscarine iodide
CAS:Muscarinic acetylcholine receptor agonistFormula:C9H20INO2Purity:98%Color and Shape:SolidMolecular weight:301.17PQCA
CAS:PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.Formula:C22H20N4O3Purity:99.88%Color and Shape:SolidMolecular weight:388.42GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37Revatropate
CAS:Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.Formula:C19H27NO4SColor and Shape:SolidMolecular weight:365.49Tridihexethyl chloride
CAS:Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.Formula:C21H36ClNOColor and Shape:SolidMolecular weight:353.97CP-601932
CAS:CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23Thonzylamine hydrochloride
CAS:Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.Formula:C16H23ClN4OPurity:99.67%Color and Shape:White Crystalline PowderMolecular weight:322.83NKY80
CAS:NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.Formula:C12H11N3O2Purity:99.88%Color and Shape:SolidMolecular weight:229.23Ref: TM-T16333
2mg44.00€5mg64.00€10mg90.00€25mg177.00€50mg309.00€100mg470.00€200mg677.00€1mL*10mM (DMSO)100.00€PHA 543613
CAS:PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.Formula:C15H17N3O2Purity:99.43% - 99.96%Color and Shape:SolidMolecular weight:271.31Ref: TM-T23145
1mg52.00€5mg102.00€10mg166.00€25mg358.00€50mg610.00€100mg895.00€500mg1,945.00€1mL*10mM (DMSO)100.00€ASM-024
CAS:ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.Formula:C15H25N2Purity:99.74%Color and Shape:SolidMolecular weight:233.37rel-(1R,2R)-Vesamicol Hydrochloride
CAS:rel-(1R,2R)-Vesamicol Hydrochloride is a acetylcholine transport inhibitor.Formula:C17H26ClNOPurity:99.88%Color and Shape:SolidMolecular weight:295.85Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Formula:C11H19IN2OPurity:99.57%Color and Shape:SolidMolecular weight:322.19Aceclidine
CAS:Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocularFormula:C9H15NO2Purity:>99.99%Color and Shape:SolidMolecular weight:169.22NB001
CAS:NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.Formula:C12H20N6OPurity:99.69%Color and Shape:Off-White To Pale Pink SolidMolecular weight:264.33Ref: TM-T16275
1mg74.00€5mg200.00€10mg295.00€25mg497.00€50mg710.00€100mg964.00€500mg1,935.00€1mL*10mM (DMSO)173.00€AQW051
CAS:AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.Formula:C19H22N2OPurity:99.94%Color and Shape:SolidMolecular weight:294.39Ref: TM-T26646
1mg34.00€2mg46.00€5mg66.00€10mg99.00€25mg205.00€50mg313.00€100mg439.00€500mg954.00€1mL*10mM (DMSO)67.00€Iperoxo
CAS:Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.Formula:C10H17IN2O2Purity:99.81%Color and Shape:SolidMolecular weight:324.16Ref: TM-T25538
1mg50.00€5mg106.00€10mg168.00€25mg339.00€50mg512.00€100mg748.00€200mg1,026.00€1mL*10mM (DMSO)117.00€Posatirelin
CAS:Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.Formula:C17H28N4O4Purity:99.43% - 99.95%Color and Shape:SolidMolecular weight:352.43PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Formula:C28H32N2O3Purity:98.39% - 99.85%Color and Shape:SolidMolecular weight:444.57Ref: TM-T33941
1mg216.00€5mg532.00€10mg758.00€25mg1,153.00€50mg1,558.00€100mg2,097.00€500mg4,204.00€1mL*10mM (DMSO)605.00€SAK3
CAS:SAK3 is a modulator of nAChR activity and is used to study memory deficits and Alzheimer's disease.Formula:C20H23N3O4Purity:98.37% - 99.43%Color and Shape:SolidMolecular weight:369.41Desformylflustrabromine hydrochloride
CAS:Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.Formula:C17H12INO5Purity:99.79%Color and Shape:SolidMolecular weight:437.19Ref: TM-T11004
2mg34.00€5mg50.00€10mg80.00€25mg145.00€50mg225.00€100mg353.00€200mg550.00€1mL*10mM (DMSO)57.00€Temiverine hydrochloride
CAS:Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.Formula:C24H36ClNO3Purity:99.26% - 99.43%Color and Shape:SolidMolecular weight:422SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Formula:C14H16N2O4Purity:98.82% - 99.93%Color and Shape:SolidMolecular weight:276.29Ref: TM-T34573
1mg112.00€5mg261.00€10mg396.00€25mg655.00€50mg888.00€100mg1,251.00€500mg2,493.00€1mL*10mM (DMSO)249.00€Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Formula:C16H25N3O5SPurity:99.1%Color and Shape:SolidMolecular weight:371.45Ref: TM-T13353
5mg35.00€10mg55.00€25mg100.00€50mg159.00€100mg245.00€200mg353.00€1mL*10mM (DMSO)39.00€Xanomeline
CAS:Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.Formula:C14H23N3OSPurity:99.61%Color and Shape:SolidMolecular weight:281.42JNJ-39393406
CAS:JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.Formula:C19H18F2N6O3Purity:98.5%Color and Shape:SolidMolecular weight:416.38Dimethindene
CAS:Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.Formula:C20H24N2Purity:98.3% - 98.99%Color and Shape:SolidMolecular weight:292.42Otenzepad
CAS:Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Formula:C24H31N5O2Purity:99.79%Color and Shape:SolidMolecular weight:421.54Ref: TM-T16411
1mg44.00€5mg79.00€10mg114.00€25mg222.00€50mg356.00€100mg572.00€200mg803.00€1mL*10mM (DMSO)87.00€CP-810123
CAS:CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.Formula:C14H18N4OPurity:98.63% - 99.60%Color and Shape:SolidMolecular weight:258.32Tribendimidine
CAS:Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.Formula:C28H32N6Purity:≥98%Color and Shape:SolidMolecular weight:452.59GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Formula:C24H29BrN2Purity:99.87% - 99.98%Color and Shape:SolidMolecular weight:425.4McN-A 343
CAS:McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.Formula:C14H18Cl2N2O2Purity:99.65%Color and Shape:SolidMolecular weight:317.21VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Formula:C24H26N6O2Purity:99.67%Color and Shape:SolidMolecular weight:430.5BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Formula:C16H19N7OPurity:98%Color and Shape:SolidMolecular weight:325.37L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Formula:C11H15N3OColor and Shape:SolidMolecular weight:205.26PTAC oxalate
CAS:muscarinic receptor ligandFormula:C14H21N3O4S2Purity:98%Color and Shape:SolidMolecular weight:359.46AR420626
CAS:AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.Formula:C21H18Cl2N2O3Purity:98.62%Color and Shape:SolidMolecular weight:417.29Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Formula:C17H22BrNOS2Purity:98%Color and Shape:SolidMolecular weight:400.4A-424274
CAS:A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.Formula:C14H15N3Purity:98%Color and Shape:SolidMolecular weight:225.29Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Formula:C9H8N2S3Color and Shape:SolidMolecular weight:240.37Muscarine tosylate
CAS:Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].Formula:C16H27NO5SColor and Shape:SolidMolecular weight:345.45N-Demethyl MK-6884
CAS:N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47UFP-512
CAS:UFP-512 is a selective delta-opioid (DOP) receptor agonist.Formula:C31H33N5O5Purity:98%Color and Shape:SolidMolecular weight:555.62
