AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Formula:C11H15ClN4O2Purity:99.03%Color and Shape:Light-Yellow CrystalMolecular weight:270.72Mecamylamine hydrochloride
CAS:Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.Formula:C11H22ClNPurity:99.76% - >99.99%Color and Shape:White SolidMolecular weight:203.75Syn-Ake acetate
CAS:Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.Formula:C19H29N5O3·2(C2H4O2)Purity:99.60%Color and Shape:SolidMolecular weight:495.58Procyclidine hydrochloride
CAS:Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.Formula:C19H30ClNOPurity:99.24% - 99.88%Color and Shape:Crystals From Petroleum Ether White PowderMolecular weight:323.9KH7
CAS:KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.Formula:C17H15BrN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:419.3Batefenterol
CAS:Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).Formula:C40H42ClN5O7Purity:97.94% - 98.4%Color and Shape:SolidMolecular weight:740.24Solifenacin hydrochloride
CAS:Solifenacin Hcl is a muscarinic receptor antagonist.Formula:C23H27ClN2O2Purity:98%Color and Shape:SolidMolecular weight:398.93Encenicline
CAS:Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.Formula:C16H17ClN2OSPurity:99.20%Color and Shape:SolidMolecular weight:320.84Ref: TM-T7193
1mg70.00€5mg133.00€10mg207.00€25mg349.00€50mg495.00€100mg675.00€200mg888.00€1mL*10mM (DMSO)144.00€Mecamylamine
CAS:Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.Formula:C11H21NColor and Shape:SolidMolecular weight:167.29Oxyphencyclimine Hydrochloride
CAS:Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.Formula:C20H29ClN2O3Purity:99.55%Color and Shape:SolidMolecular weight:380.91Dinotefuran
CAS:Dinotefuran (MTI-446), a neonicotinoid insecticide, targets pests by blocking their nervous system.Formula:C7H14N4O3Purity:99.89%Color and Shape:White Crystalline PowderMolecular weight:202.21Propiverine
CAS:Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.Formula:C23H29NO3Color and Shape:SolidMolecular weight:367.48NS 1738
CAS:NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)Formula:C14H9Cl2F3N2O2Purity:99.11%Color and Shape:SolidMolecular weight:365.13Sofpironium bromide
CAS:Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.Formula:C22H32BrNO5Purity:98.85%Color and Shape:SolidMolecular weight:470.4Ref: TM-T28827
1mg74.00€5mg160.00€10mg250.00€25mg452.00€50mg680.00€100mg1,008.00€200mg1,349.00€1mL*10mM (DMSO)165.00€ZSET1446
CAS:ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.Formula:C15H12N2OPurity:99.32%Color and Shape:SolidMolecular weight:236.27Ref: TM-T8448
1mg50.00€5mg103.00€10mg144.00€25mg281.00€50mg409.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)119.00€EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purity:99.48%Color and Shape:SolidMolecular weight:644.4Ref: TM-T7955
1mg87.00€2mg114.00€5mg177.00€10mg260.00€25mg447.00€50mg620.00€100mg875.00€200mg1,161.00€1mL*10mM (DMSO)263.00€Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurity:98.85% - 99.99%Color and Shape:SolidMolecular weight:556.76Pempidine
CAS:Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.Formula:C10H21NPurity:98.18% - 99.28%Color and Shape:Colorless - Light Yellow Clear LiquidMolecular weight:155.28Oxyphenonium bromide
CAS:Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.
Formula:C21H34BrNO3Purity:98.96%Color and Shape:SolidMolecular weight:428.404MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Formula:C35H43N7O11Purity:97.2% - 98.055%Color and Shape:SolidMolecular weight:737.76Propantheline
CAS:Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.Formula:C23H30NO3Color and Shape:SolidMolecular weight:368.49Simufilam dihydrochloride
CAS:Simufilam dihydrochloride is an oral, low-toxic FLNA activator for Alzheimer's research, restoring FLNA structure and function.Formula:C15H23Cl2N3OPurity:98.83%Color and Shape:SolidMolecular weight:332.3Ref: TM-T9172
1mg49.00€5mg95.00€10mg136.00€25mg279.00€50mg360.00€100mg470.00€200mg622.00€1mL*10mM (DMSO)96.00€VU0357017 hydrochloride
CAS:VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.Formula:C18H28ClN3O3Purity:99% - 99.97%Color and Shape:SolidMolecular weight:369.89Iptakalim Hydrochloride
CAS:Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormula:C9H22ClNPurity:98%Color and Shape:SolidMolecular weight:179.731Bestim
CAS:Bestim is an immunomodulatory dipeptide that is synthetic.Formula:C16H19N3O5Purity:99.76%Color and Shape:SolidMolecular weight:333.34Ref: TM-T25146
1mg84.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)172.00€VU0152099
CAS:VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).Formula:C18H17N3O3SPurity:98.46%Color and Shape:SolidMolecular weight:355.41Pempidine HCl
CAS:Pempidine HCl, a nicotinic antagonist and former hypertension treatment, now mainly serves as a lab tool.Formula:C10H22ClNColor and Shape:SolidMolecular weight:191.74Rivanicline hemioxalate
Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:207.23suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Formula:C11H14Cl2N2OPurity:98.88%Color and Shape:SolidMolecular weight:261.15Ref: TM-T9787
1mg67.00€5mg133.00€10mg205.00€25mg339.00€50mg482.00€100mg658.00€200mg888.00€1mL*10mM (DMSO)172.00€Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Formula:C19H23N3O3Purity:99.96%Color and Shape:SolidMolecular weight:341.4Aclidinium bromide
CAS:Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.
Formula:C26H30NO4S2·BrPurity:99.53% - 99.69%Color and Shape:SolidMolecular weight:564.55Encenicline hydrochloride
CAS:Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).Formula:C16H17ClN2OS·HClPurity:98.34% - 99.85%Color and Shape:SolidMolecular weight:357.3Adiphenine
CAS:Adiphenine is an inhibitor of nicotinic receptors.Formula:C20H25NO2Color and Shape:SolidMolecular weight:311.42Irsogladine
CAS:Irsogladine (Dicloguamine) is an anti-ulcer agent that promotes gap junction intercellular communication via M1 muscarinic acetylcholine receptor binding.Formula:C9H7Cl2N5Purity:99.74% - 99.91%Color and Shape:White Or Colorless Crystal Or Crystalline Powder Odorless Slightly BitterMolecular weight:256.09VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7Benzetimide hydrochloride
CAS:Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.Formula:C23H27ClN2O2Purity:99.32%Color and Shape:Off-White PowderMolecular weight:398.93Oxyphencyclimine
CAS:Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.Formula:C20H28N2O3Color and Shape:SolidMolecular weight:344.45(S)-UFR2709
CAS:(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.Formula:C13H17NO2Color and Shape:SolidMolecular weight:219.284mAChR-IN-1 hydrochloride
CAS:mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.Formula:C23H26ClIN2O2Purity:99.87%Color and Shape:SolidMolecular weight:524.82Ref: TM-T5655
1mg38.00€5mg86.00€10mg126.00€25mg215.00€50mg298.00€100mg371.00€200mg494.00€1mL*10mM (DMSO)89.00€Batefenterol Succinate
CAS:Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.Formula:C44H48ClN5O11Color and Shape:SolidMolecular weight:858.34Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purity:99.87%Color and Shape:SolidMolecular weight:362.46LY2119620
CAS:LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.Formula:C19H24ClN5O3SPurity:99.7%Color and Shape:SolidMolecular weight:437.94Pirmenol
CAS:Pirmenol is a new antiarrhythmic drugFormula:C22H30N2OPurity:97.24%Color and Shape:SolidMolecular weight:338.49GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formula:C28H24F3N7O2Purity:97.05% - 99.7%Color and Shape:SolidMolecular weight:547.53Darifenacin
CAS:Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used to study urinary incontinence and overactive bladder.Formula:C28H30N2O2Purity:99.78%Color and Shape:SolidMolecular weight:426.55Ref: TM-T62320
2mg39.00€5mg58.00€10mg93.00€25mg152.00€50mg236.00€100mg356.00€200mg522.00€1mL*10mM (DMSO)64.00€Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purity:99.35%Color and Shape:SolidMolecular weight:218.68Ilmetropium iodide
CAS:Ilmetropium iodide is a bronchodilator.Formula:C20H30INO3Purity:98.45%Color and Shape:SolidMolecular weight:459.36Brompheniramine
CAS:Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.Formula:C16H19BrN2Color and Shape:SolidMolecular weight:319.24Ursulcholic acid
CAS:Ursulcholic acid (Ursulcholic) is a water-soluble anticholinergic compound.Formula:C24H40O10S2Purity:98%Color and Shape:SolidMolecular weight:552.7Nor-benzetimide
CAS:Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.Formula:C16H20N2O2Purity:98.63%Color and Shape:SolidMolecular weight:272.34Ref: TM-T22380
1mg72.00€5mg136.00€10mg197.00€25mg324.00€50mg452.00€100mg607.00€200mg810.00€1mL*10mM (DMSO)135.00€
