AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
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Isopropamide Iodide
CAS:<p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>Formula:C23H33IN2OPurity:99.67%Color and Shape:SolidMolecular weight:480.43SQ22536
CAS:<p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>Formula:C9H11N5OPurity:99.18%Color and Shape:Off-White SolidMolecular weight:205.22Tacrine hydrochloride (hydrate)
CAS:<p>Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.</p>Formula:C13H14N2·XHCl·XH2OPurity:99.01% - 99.89%Color and Shape:SolidMolecular weight:234.72A 582941 HCl (848591-90-2(free base))
<p>A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties</p>Formula:C17H21ClN4Purity:99.83%Color and Shape:SolidMolecular weight:316.83ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Atracurium besylate
CAS:<p>Atracurium besylate (51W89) is a short-acting, non-depolarizing muscle relaxant, not affecting the heart or reliant on kidneys.</p>Formula:C65H82N2O18S2Purity:98.94% - 99.71%Color and Shape:SolidMolecular weight:1243.49VU0467154
CAS:<p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>Formula:C17H15F3N4O3S2Purity:98.28% - 99.51%Color and Shape:SolidMolecular weight:444.45suvn-911
CAS:<p>suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.</p>Formula:C11H14Cl2N2OPurity:98.88%Color and Shape:SolidMolecular weight:261.159-Ethyladenine
CAS:<p>9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1].</p>Formula:C7H9N5Purity:99.35% - 99.41%Color and Shape:SolidMolecular weight:163.18VU0152099
CAS:<p>VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).</p>Formula:C18H17N3O3SPurity:98.46%Color and Shape:SolidMolecular weight:355.41VU0152100
CAS:<p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>Formula:C18H19N3O2SPurity:99.56%Color and Shape:SolidMolecular weight:341.43TBPB
CAS:<p>TBPB is an allosteric M1 mAChR agonist.</p>Formula:C25H32N4OPurity:97.87% - 99.9%Color and Shape:SolidMolecular weight:404.55Tebanicline hydrochloride
CAS:<p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>Formula:C9H12Cl2N2OPurity:91.74% - 98.71%Color and Shape:SolidMolecular weight:235.11Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Formula:C20H30BrNO3Purity:99.92%Color and Shape:SolidMolecular weight:412.37VU0119498
CAS:<p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>Formula:C15H10BrNO2Purity:97.56%Color and Shape:SolidMolecular weight:316.15Dicyclomine
CAS:<p>Dicyclomine: oral muscarinic antagonist, eases GI muscle spasms, high affinity for M1/M2 receptors, Ki of 5.1 nM/54.6 nM.</p>Formula:C19H35NO2Color and Shape:SolidMolecular weight:309.49Batefenterol
CAS:<p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>Formula:C40H42ClN5O7Purity:97.94% - 98.4%Color and Shape:SolidMolecular weight:740.24KH7
CAS:<p>KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.</p>Formula:C17H15BrN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:419.3Piperidolate hydrochloride
CAS:<p>Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.</p>Formula:C21H26ClNO2Purity:99.5%Color and Shape:SolidMolecular weight:359.89Bestim
CAS:<p>Bestim is an immunomodulatory dipeptide that is synthetic.</p>Formula:C16H19N3O5Purity:99.76%Color and Shape:SolidMolecular weight:333.34VU0357017 hydrochloride
CAS:<p>VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.</p>Formula:C18H28ClN3O3Purity:99% - 99.97%Color and Shape:SolidMolecular weight:369.89Succinylcholine Chloride Dihydrate
CAS:<p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>Formula:C14H30N2O4·2Cl·2H2OPurity:99.87%Color and Shape:White SolidMolecular weight:397.34VU10010
CAS:<p>VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.</p>Formula:C17H16ClN3OSPurity:99.36%Color and Shape:SolidMolecular weight:345.85Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Formula:C19H30ClNOPurity:99.24% - 99.88%Color and Shape:Crystals From Petroleum Ether White PowderMolecular weight:323.9Oxotremorine sesquifumarate
CAS:<p>Oxotremorine sesquifumarate is a muscarinic agonist.</p>Formula:C12H18N2OC4H4O4Purity:97.94%Color and Shape:SolidMolecular weight:380.39α-Conotoxin MII acetate
<p>α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus.</p>Formula:C69H107N23O24S4Purity:94.82% - 97.79%Color and Shape:SolidMolecular weight:1770.99Syn-Ake acetate
CAS:<p>Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.</p>Formula:C19H29N5O3·2(C2H4O2)Purity:99.60%Color and Shape:SolidMolecular weight:495.58Clothianidin
CAS:<p>Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.</p>Formula:C6H8ClN5O2SPurity:99.71% - 99.87%Color and Shape:Solid PowderMolecular weight:249.68JHU37152
CAS:<p>JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.</p>Formula:C19H20ClFN4Purity:99.72%Color and Shape:SolidMolecular weight:358.84Varenicline Tartrate
CAS:<p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>Formula:C13H13N3·C4H6O6Purity:98.23% - 98.32%Color and Shape:Tan SolidMolecular weight:361.35TQS
CAS:<p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>Formula:C22H20N2O2SPurity:98.56%Color and Shape:SolidMolecular weight:376.47Sofpironium bromide
CAS:<p>Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.</p>Formula:C22H32BrNO5Purity:98.85%Color and Shape:SolidMolecular weight:470.4Dinotefuran
CAS:<p>Dinotefuran (MTI-446), a neonicotinoid insecticide, targets pests by blocking their nervous system.</p>Formula:C7H14N4O3Purity:99.89%Color and Shape:White Crystalline PowderMolecular weight:202.21MC-Val-Cit-PAB
CAS:<p>MC-Val-Cit-PAB: cathepsin-cleavable ADC linker used in FDA-approved brentuximab vedotin.</p>Formula:C28H40N6O7Purity:98.24%Color and Shape:SolidMolecular weight:572.65Revefenacin
CAS:<p>Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.</p>Formula:C35H43N5O4Purity:98.12%Color and Shape:SolidMolecular weight:597.75Pempidine
CAS:<p>Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.</p>Formula:C10H21NPurity:98.18% - 99.28%Color and Shape:Colorless - Light Yellow Clear LiquidMolecular weight:155.28Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.76Nitrocaramiphen hydrochloride
CAS:<p>Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.</p>Formula:C18H27ClN2O4Purity:99.74%Color and Shape:SolidMolecular weight:370.87Anisotropine Methylbromide
CAS:<p>Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.</p>Formula:C17H32BrNO2Purity:99.73%Color and Shape:Crystals From Acetone SolidMolecular weight:362.35Solifenacin
CAS:<p>Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,</p>Formula:C23H26N2O2Purity:99.87%Color and Shape:SolidMolecular weight:362.46Piperidolate
CAS:<p>Piperidolate inhibits intestinal cramp induced by acetylcholine</p>Formula:C21H25NO2Purity:98.45%Color and Shape:SolidMolecular weight:323.43PNU-282987 S enantiomer free base
CAS:<p>PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).</p>Formula:C14H17ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:264.75VU 0238429
CAS:<p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>Formula:C17H12F3NO4Purity:>99.99%Color and Shape:SolidMolecular weight:351.28VU0238441
CAS:<p>VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.</p>Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7Glycopyrrolate
CAS:<p>Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.</p>Formula:C19H28BrNO3Purity:99.41% - 99.64%Color and Shape:SolidMolecular weight:398.33PHA 543613 hydrochloride
CAS:<p>PHA-543613 hydrochloride, a potent α7 nicotinic receptor agonist, may treat schizophrenia-related cognitive deficits.</p>Formula:C15H18ClN3O2Color and Shape:SolidMolecular weight:307.78Nitenpyram
CAS:<p>Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.</p>Formula:C11H15ClN4O2Purity:99.03%Color and Shape:Light-Yellow CrystalMolecular weight:270.72Harman hydrochloride
CAS:<p>Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.</p>Formula:C12H11ClN2Purity:99.35%Color and Shape:SolidMolecular weight:218.68CCMI
CAS:<p>CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.</p>Formula:C19H15Cl2N3O2Purity:>99.99%Color and Shape:SolidMolecular weight:388.25W-84 dibromide
CAS:<p>W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.</p>Formula:C32H44Br2N4O4Purity:95.56%Color and Shape:SolidMolecular weight:708.52
