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NMDAR

NMDAR

N-Methyl-D-Aspartate Receptor (NMDAR) inhibitors are compounds that block the activity of NMDARs, a subtype of glutamate receptors that play a critical role in synaptic plasticity, learning, and memory. Overactivation of NMDARs is implicated in excitotoxicity, which can lead to neuronal damage and is associated with conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. NMDAR inhibitors are essential tools for studying excitotoxicity and for developing neuroprotective therapies. At CymitQuimica, we offer a range of NMDAR inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.

Found 28 products of "NMDAR"

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  • MDL-29951
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    MDL-29951

    CAS:
    <p>MDL-29951 is a novel glycine antagonist of NMDA receptor activation.</p>
    Formula:C12H9Cl2NO4
    Purity:98.79% - 99.49%
    Color and Shape:Solid
    Molecular weight:302.11

    Ref: TM-T1897

  • Dizocilpine
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    Dizocilpine

    CAS:
    <p>MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.</p>
    Formula:C16H15N
    Purity:99.85% - 99.97%
    Color and Shape:Solid
    Molecular weight:221.3

    Ref: TM-T6259

  • Gavestinel sodium
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    Gavestinel sodium

    CAS:
    <p>Gavestinel (GV 150526): potent, selective oral NMDA antagonist; binds glycine site, pKi 8.5; studied for acute ischemic stroke.</p>
    Formula:C18H11Cl2N2NaO3
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:397.19

    Ref: TM-T22798

  • UK-240455
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    UK-240455

    CAS:
    <p>UK-240455: Potent NMDA glycine antagonist with neuroprotection and motor function benefits in Parkinson's.</p>
    Formula:C11H11Cl2N3O5S
    Purity:98.34% - 99.84%
    Color and Shape:Solid
    Molecular weight:368.19

    Ref: TM-T13248

  • CGP 37849
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    CGP 37849

    CAS:
    <p>CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.</p>
    Formula:C6H12NO5P
    Purity:99.87%
    Color and Shape:White Solid
    Molecular weight:209.14

    Ref: TM-T7720

  • Dalzanemdor
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    Dalzanemdor

    CAS:
    <p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>
    Formula:C27H43F3O2
    Purity:98.2% - >99.99%
    Color and Shape:Solid
    Molecular weight:456.62

    Ref: TM-T62839

  • CGP 78608 hydrochloride
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    CGP 78608 hydrochloride

    CAS:
    <p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>
    Formula:C11H14BrClN3O5P
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:414.58

    Ref: TM-T10781

  • R-(+)-EU-1180-453
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    R-(+)-EU-1180-453

    CAS:
    <p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>
    Formula:C22H21FN2O3
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:380.41

    Ref: TM-T69611