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Serine Protease

Serine Protease

Serine protease inhibitors are compounds that target and inhibit serine proteases, a group of enzymes characterized by a serine residue at their active site. These proteases are involved in numerous physiological processes, including digestion, immune response, blood coagulation, and inflammation. Serine protease inhibitors are important for studying diseases where these enzymes are dysregulated, such as cardiovascular diseases, cancer, and inflammatory conditions. At CymitQuimica, we provide serine protease inhibitors to support your research in enzymology, disease mechanisms, and therapeutic interventions.

Found 56 products of "Serine Protease"

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  • ZD-0892

    CAS:
    <p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>
    Formula:C24H32F3N3O5
    Purity:95% - 99.53%
    Color and Shape:Solid
    Molecular weight:499.52
  • AGLME

    CAS:
    AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.
    Formula:C11H21N3O4
    Color and Shape:Solid
    Molecular weight:259.3
  • BMS-363131

    CAS:
    BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.
    Formula:C28H40N6O5
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:540.65
  • WNK1-IN-1

    CAS:
    WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.
    Formula:C13H15BrCl2N2O4S
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:446.14
  • Lodelaben

    CAS:
    Lodelaben (Declaben, SC-39026) is a reversible, non-competitive,specific inhibitor of human neutrophil elastase (HNE) with high potency (IC50=0.5 μM).
    Formula:C25H41ClO3
    Purity:99.62% - >99.99%
    Color and Shape:Solid
    Molecular weight:425.04
  • APC 366

    CAS:
    APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).
    Formula:C22H28N6O4
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:440.5
  • IPR-803

    CAS:
    IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.
    Formula:C27H23N3O4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:453.49
  • ZD8321

    CAS:
    <p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>
    Formula:C18H28F3N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:423.43
  • ZM223 hydrochloride (2031177-48-5 free base)


    ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
    Formula:C23H18ClF3N4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.99
  • FK706

    CAS:
    FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.
    Formula:C26H33F3N4NaO7
    Color and Shape:Solid
    Molecular weight:593.556
  • LM-030

    CAS:
    LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).
    Formula:C46H72N8O12
    Color and Shape:Solid
    Molecular weight:929.11
  • AZD-9819

    CAS:
    AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).
    Formula:C25H19F3N6O2
    Purity:100% - 99.18%
    Color and Shape:Solid
    Molecular weight:492.45
  • TMPRSS6-IN-1 TFA


    TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.
    Formula:C35H41F3N8O6S2
    Color and Shape:Solid
    Molecular weight:790.875
  • Matriptase-IN-2 free base

    CAS:
    Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].
    Formula:C29H33Cl2N5O3S
    Color and Shape:Solid
    Molecular weight:602.58
  • MeO-Suc-Ala-Ala-Pro-Ala-CMK

    CAS:
    MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).
    Formula:C20H31ClN4O7
    Color and Shape:Solid
    Molecular weight:474.936
  • Feniralstat

    CAS:
    Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.
    Formula:C26H25F2N5O4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:509.51