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PAI-1

PAI-1

Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.

Found 31 products for "PAI-1".

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  • UK-371804 HCl

    CAS:
    UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-
    Formula:C14H17Cl2N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:422.29

    Ref: TM-T22451

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Diaplasinin

    CAS:
    Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.
    Formula:C32H31N5O
    Purity:99.75%
    Color and Shape:Yellow Solid
    Molecular weight:501.62

    Ref: TM-T25915

    1mg
    57.00€
    5mg
    120.00€
    1mL*10mM (DMSO)
    133.00€
    10mg
    178.00€
    25mg
    409.00€
    50mg
    708.00€
    100mg
    1,153.00€
  • p-Aminobenzamidine dihydrochloride

    CAS:
    4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type
    Formula:C7H11Cl2N3
    Purity:99.00% - 99.77%
    Color and Shape:Solid
    Molecular weight:208.088

    Ref: TM-T60248

    2g
    33.00€
    1mL*10mM (DMSO)
    33.00€
  • CT140


    CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1069

    1mg
    To inquire
    5mg
    To inquire
  • Aleplasinin

    CAS:
    Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic
    Formula:C28H27NO3
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:425.52

    Ref: TM-T29856

    1mg
    54.00€
    5mg
    114.00€
    1mL*10mM (DMSO)
    126.00€
    10mg
    178.00€
    25mg
    409.00€
    50mg
    620.00€
    100mg
    982.00€
    200mg
    1,314.00€
  • AZ3976

    CAS:
    AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.
    Formula:C15H19N5O3
    Purity:98.14%
    Color and Shape:White Solid
    Molecular weight:317.34

    Ref: TM-T23764

    5mg
    34.00€
    1mL*10mM (DMSO)
    44.00€
    10mg
    52.00€
    25mg
    92.00€
    50mg
    122.00€
  • ZK824190

    CAS:
    ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.
    Formula:C22H20F2N2O4
    Purity:98.84%
    Color and Shape:White Solid
    Molecular weight:414.4

    Ref: TM-T13408

    1mg
    152.00€
    5mg
    306.00€
    1mL*10mM (DMSO)
    318.00€
    10mg
    442.00€
    25mg
    675.00€
    50mg
    900.00€
    100mg
    1,224.00€
  • PPACK

    CAS:
    PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.
    Formula:C21H31ClN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.96

    Ref: TM-T20505

    5mg
    269.00€
    10mg
    454.00€
    25mg
    852.00€
  • BT-114143

    CAS:
    BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.
    Formula:C8H11N2O3P
    Color and Shape:Solid
    Molecular weight:214.158

    Ref: TM-T206847

    25mg
    1,468.00€
    50mg
    1,972.00€
    100mg
    2,440.00€
  • GGACK

    CAS:
    GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).
    Formula:C14H25ClN6O5
    Color and Shape:Solid
    Molecular weight:392.84

    Ref: TM-TP3280

    10mg
    To inquire
    50mg
    To inquire
  • GGACK hydrochloride


    GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).
    Formula:C14H26Cl2N6O5
    Color and Shape:Solid
    Molecular weight:428.13417

    Ref: TM-T207613

    10mg
    Discontinued
    50mg
    Discontinued
    Discontinued product