PAI-1
Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.
Found 25 products of "PAI-1"
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PPACK
CAS:<p>PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.</p>Formula:C21H31ClN6O3Purity:98%Color and Shape:SolidMolecular weight:450.96GW-6604
CAS:<p>GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.</p>Formula:C19H14N4Purity:99.6%Color and Shape:SolidMolecular weight:298.34ZK824190
CAS:<p>ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.</p>Formula:C22H20F2N2O4Purity:98.84%Color and Shape:SolidMolecular weight:414.4BT-114143
CAS:<p>BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.</p>Formula:C8H11N2O3PColor and Shape:SolidMolecular weight:214.158GGACK
CAS:<p>GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formula:C14H25ClN6O5Molecular weight:392.84
