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Cysteine Protease

Cysteine Protease

Cysteine Protease inhibitors are compounds that target and inhibit cysteine proteases, a class of enzymes that break down proteins by cleaving peptide bonds in which a cysteine residue acts as the nucleophile. These enzymes are involved in various physiological processes, including apoptosis, immune response, and protein turnover. Cysteine protease inhibitors are crucial for studying diseases such as cancer, neurodegenerative disorders, and parasitic infections. At CymitQuimica, we provide cysteine protease inhibitors to aid your research in proteolysis, cellular regulation, and drug discovery.

Found 96 products of "Cysteine Protease"

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  • VK13


    <p>VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.</p>
    Formula:C24H28N4O5
    Color and Shape:Solid
    Molecular weight:452.503
  • Mpro/Cathepsin L-IN-1


    <p>Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.</p>
    Formula:C24H32FN3O4
    Molecular weight:445.23768
  • Z-FG-NHO-Bz

    CAS:
    <p>Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].</p>
    Formula:C26H25N3O6
    Color and Shape:Solid
    Molecular weight:475.49
  • Z-Phe-Tyr(tBu)-diazomethylketone

    CAS:
    <p>Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.</p>
    Formula:C31H34N4O5
    Color and Shape:Solid
    Molecular weight:542.636
  • Z-L(D-Val)G-CHN2


    <p>Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.</p>
    Formula:C22H31N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:445.51
  • Relacatib

    CAS:
    <p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64
  • LN5P45


    <p>LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1</p>
    Formula:C13H15ClN2O2
    Color and Shape:Solid
    Molecular weight:266.72
  • Odanacatib

    CAS:
    <p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>
    Formula:C25H27F4N3O3S
    Purity:98.53% - 99.53%
    Color and Shape:Solid
    Molecular weight:525.56
  • JTE-607

    CAS:
    <p>JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.</p>
    Formula:C25H33Cl4N3O5
    Purity:97.88%
    Color and Shape:Solid
    Molecular weight:597.36
  • E-64

    CAS:
    <p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>
    Formula:C15H27N5O5
    Purity:98% - 99.95%
    Color and Shape:White Solid
    Molecular weight:357.41
  • KGP94

    CAS:
    <p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>
    Formula:C14H12BrN3OS
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:350.23
  • Balicatib

    CAS:
    <p>Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.</p>
    Formula:C23H33N5O2
    Purity:97.78% - 98.17%
    Color and Shape:White To Off-White Solid Powder
    Molecular weight:411.54
  • 2-Cyanopyrimidine

    CAS:
    <p>2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)</p>
    Formula:C5H3N3
    Purity:99.27%
    Color and Shape:Crystalline Solid
    Molecular weight:105.1
  • L-006235

    CAS:
    <p>L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.</p>
    Formula:C24H30N6O2S
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:466.6
  • MDL-28170

    CAS:
    <p>MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.</p>
    Formula:C22H26N2O4
    Purity:95.06%
    Color and Shape:Solid
    Molecular weight:382.45
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Formula:C19H31N3O6
    Purity:97.26% - 99.58%
    Color and Shape:Solid
    Molecular weight:397.47
  • LY 3000328

    CAS:
    <p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>
    Formula:C25H29FN4O5
    Purity:97.83% - 99.54%
    Color and Shape:Solid
    Molecular weight:484.52
  • (1S,2R)-Alicapistat

    CAS:
    <p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>
    Formula:C25H27N3O4
    Purity:99.60%
    Color and Shape:Soild
    Molecular weight:433.5
  • Cathepsin Inhibitor 1

    CAS:
    <p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>
    Formula:C20H24ClN5O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:401.89
  • GSK2793660 HCl

    CAS:
    <p>GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.</p>
    Formula:C22H32ClN3O3
    Color and Shape:Solid
    Molecular weight:421.96