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Protease-activated Receptor

Protease-activated Receptor

Protease-activated Receptor (PAR) inhibitors are compounds that target and inhibit the activity of PARs, a family of G-protein-coupled receptors that are activated by proteolytic cleavage. These receptors play a role in various physiological processes, including coagulation, inflammation, and tissue repair. PAR inhibitors are valuable tools for studying the mechanisms of these processes and their involvement in diseases such as cancer, cardiovascular disorders, and chronic inflammation. At CymitQuimica, we provide PAR inhibitors to aid your research in signal transduction, immune response, and therapeutic discovery.

Found 54 products of "Protease-activated Receptor"

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  • PAR4 antagonist 3

    CAS:
    PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.
    Formula:C22H16FN3O5S
    Molecular weight:453.44

    Ref: TM-T209701

    10mg
    To inquire
    50mg
    To inquire
  • PAR-2-IN-2

    CAS:
    PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.
    Formula:C25H20F3N5O2
    Color and Shape:Solid
    Molecular weight:479.454

    Ref: TM-T204647

    10mg
    To inquire
    50mg
    To inquire
  • BMS-986141

    CAS:
    BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614
    Formula:C27H23N5O5S2
    Purity:98.43% - 99.26%
    Color and Shape:Solid
    Molecular weight:561.63

    Ref: TM-T63966

    1mg
    612.00€
    5mg
    1,216.00€
    10mg
    1,549.00€
    25mg
    2,213.00€
  • Protease-Activated Receptor-4

    CAS:
    Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.
    Formula:C33H46N8O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:666.77

    Ref: TM-T7380

    1mg
    Discontinued
    Discontinued product