
Protease-activated Receptor
Protease-activated Receptor (PAR) inhibitors are compounds that target and inhibit the activity of PARs, a family of G-protein-coupled receptors that are activated by proteolytic cleavage. These receptors play a role in various physiological processes, including coagulation, inflammation, and tissue repair. PAR inhibitors are valuable tools for studying the mechanisms of these processes and their involvement in diseases such as cancer, cardiovascular disorders, and chronic inflammation. At CymitQuimica, we provide PAR inhibitors to aid your research in signal transduction, immune response, and therapeutic discovery.
Found 54 products of "Protease-activated Receptor"
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PAR4 antagonist 3
CAS:PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.Formula:C22H16FN3O5SMolecular weight:453.44PAR-2-IN-2
CAS:PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.Formula:C25H20F3N5O2Color and Shape:SolidMolecular weight:479.454BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purity:98.43% - 99.26%Color and Shape:SolidMolecular weight:561.63Protease-Activated Receptor-4
CAS:Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formula:C33H46N8O7Purity:98%Color and Shape:SolidMolecular weight:666.77
